Magnesium in PDB 6rie: Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex

All present enzymatic activity of Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex:
2.1.1.56; 2.7.7.6;

The structure of Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex also contains other interesting chemical elements:

Zinc

(Zn)

4 atoms

The binding sites of Magnesium atom in the Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex (pdb code 6rie). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex, PDB code: 6rie:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1301 b:21.5 occ:1.00 OD1 A:ASP417 2.1 21.1 1.0 OD1 A:ASP419 2.1 21.3 1.0 O3' P:G30 2.1 29.8 1.0 CG A:ASP419 2.8 21.3 1.0 OD2 A:ASP419 2.8 21.3 1.0 CG A:ASP417 3.0 21.1 1.0 OD2 A:ASP417 3.2 21.1 1.0 CB A:ASP415 3.5 20.0 1.0 C3' P:G30 3.5 29.8 1.0 O2' P:G30 4.0 29.8 1.0 C4' P:G30 4.1 29.8 1.0 O A:ASP415 4.2 20.0 1.0 N A:ASP415 4.2 20.0 1.0 CB A:ASP419 4.2 21.3 1.0 CA A:ASP415 4.3 20.0 1.0 CG A:ASP415 4.3 20.0 1.0 C2' P:G30 4.3 29.8 1.0 CB A:ASP417 4.4 21.1 1.0 C A:ASP415 4.4 20.0 1.0 C5' P:G30 4.6 29.8 1.0 OD2 A:ASP415 4.6 20.0 1.0 N A:ASP419 4.6 21.3 1.0 N A:ASP417 4.7 21.1 1.0 CA A:ASP419 4.8 21.3 1.0 CA A:ASP417 4.9 21.1 1.0 C A:ASP417 5.0 21.1 1.0

Magnesium binding site 2 out of 2 in the Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Vaccinia Virus Dna-Dependent Rna Polymerase Co- Transcriptional Capping Complex within 5.0Å range: probe atom residue distance (Å) B Occ O:Mg902 b:42.9 occ:1.00 OE1 O:GLU194 2.4 49.5 1.0 OE1 O:GLU39 2.6 52.1 1.0 OE1 O:GLU192 3.0 43.1 1.0 OE2 O:GLU37 3.0 53.3 1.0 O2B P:GDP1 3.3 59.4 1.0 CD O:GLU194 3.6 49.5 1.0 CD O:GLU39 3.7 52.1 1.0 O1A P:GDP1 3.7 59.4 1.0 NZ O:LYS107 4.0 52.2 1.0 OE2 O:GLU39 4.1 52.1 1.0 CD O:GLU192 4.1 43.1 1.0 CD O:GLU37 4.2 53.3 1.0 OE2 O:GLU194 4.2 49.5 1.0 PB P:GDP1 4.5 59.4 1.0 O2A P:GDP1 4.5 59.4 1.0 PA P:GDP1 4.6 59.4 1.0 OE2 O:GLU192 4.6 43.1 1.0 OE1 O:GLU37 4.7 53.3 1.0 O1B P:GDP1 4.8 59.4 1.0 CG O:GLU194 4.8 49.5 1.0 OD2 O:ASP159 4.9 37.6 1.0 CG O:GLU39 4.9 52.1 1.0 O3A P:GDP1 5.0 59.4 1.0

H.S.Hillen, J.Bartuli, C.Grimm, C.Dienemann, K.Bedenk, A.A.Szalay, U.Fischer, P.Cramer. Structural Basis of Poxvirus Transcription: Transcribing and Capping Vaccinia Complexes. Cell V. 179 1525 2019.
ISSN: ISSN 1097-4172
PubMed: 31835031
DOI: 10.1016/J.CELL.2019.11.023