Magnesium in PDB 6rin: Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor

Enzymatic activity of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor

All present enzymatic activity of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor:
2.7.7.6;

Other elements in 6rin:

The structure of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor (pdb code 6rin). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor, PDB code: 6rin:

Magnesium binding site 1 out of 1 in 6rin

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Magnesium Binding Sites List in 6rin

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of E. Coli Rna Polymerase Backtracked Elongation Complex Bound to Greb Transcription Factor within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
D:Mg1503 b:54.5 occ:1.00	OP1	R:U11	2.0	74.1	1.0
	OD1	D:ASP460	2.3	50.8	1.0
	OD1	D:ASP462	2.3	48.3	1.0
	OD2	D:ASP462	2.5	48.3	1.0
	CG	D:ASP462	2.7	48.3	1.0
	O3'	R:G10	2.8	61.6	1.0
	OD1	D:ASP464	2.9	43.7	1.0
	P	R:U11	2.9	74.1	1.0
	OD2	D:ASP460	3.0	50.8	1.0
	CG	D:ASP460	3.0	50.8	1.0
	OD2	D:ASP464	3.2	43.7	1.0
	CG	D:ASP464	3.4	43.7	1.0
	C5'	R:U11	3.4	74.1	1.0
	O5'	R:U11	3.7	74.1	1.0
	C3'	R:G10	4.2	61.6	1.0
	CB	D:ASP462	4.2	48.3	1.0
	OP2	R:U11	4.2	74.1	1.0
	OE2	F:GLU44	4.3	66.7	1.0
	O2'	R:G10	4.4	61.6	1.0
	CB	D:ASP460	4.4	50.8	1.0
	NH2	D:ARG425	4.4	40.5	1.0
	OD1	F:ASP41	4.6	73.2	1.0
	N	D:ASP460	4.7	50.8	1.0
	C4'	R:G10	4.7	61.6	1.0
	N	D:ASP462	4.8	48.3	1.0
	CD	F:GLU44	4.9	66.7	1.0
	C4'	R:U11	4.9	74.1	1.0
	CB	D:ASP464	4.9	43.7	1.0
	C2'	R:G10	4.9	61.6	1.0
	O	D:ASP460	4.9	50.8	1.0
	CA	D:ASP462	5.0	48.3	1.0
	OE1	F:GLU44	5.0	66.7	1.0
	CA	D:ASP460	5.0	50.8	1.0

Reference:

M.Abdelkareem, C.Saint-Andre, M.Takacs, G.Papai, C.Crucifix, X.Guo, J.Ortiz, A.Weixlbaumer. Structural Basis of Transcription: Rna Polymerase Backtracking and Its Reactivation. Mol.Cell V. 75 298 2019.
ISSN: ISSN 1097-2765
PubMed: 31103420
DOI: 10.1016/J.MOLCEL.2019.04.029

Page generated: Tue Oct 1 17:00:52 2024

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