Atomistry » Magnesium » PDB 6s43-6ses » 6sbi
Atomistry »
  Magnesium »
    PDB 6s43-6ses »
      6sbi »

Magnesium in PDB 6sbi: X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate

Enzymatic activity of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate

All present enzymatic activity of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate:
3.7.1.5; 4.1.1.112;

Protein crystallography data

The structure of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate, PDB code: 6sbi was solved by B.Rupp, A.Naschberger, A.K.H.Weiss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 44.37 / 2.70
Space group P 1 21 1
Cell size a, b, c (Å), α, β, γ (°) 52.603, 103.348, 86.597, 90.00, 90.21, 90.00
R / Rfree (%) 18.7 / 23.4

Other elements in 6sbi:

The structure of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate also contains other interesting chemical elements:

Potassium (K) 2 atoms
Chlorine (Cl) 9 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate (pdb code 6sbi). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate, PDB code: 6sbi:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in 6sbi

Go back to Magnesium Binding Sites List in 6sbi
Magnesium binding site 1 out of 4 in the X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg301

b:20.5
occ:1.00
 O A:HOH404 2.1 13.7 1.0
OE2 A:GLU76 2.1 19.5 1.0
OD2 A:ASP105 2.1 22.1 1.0
O1 A:OXL306 2.1 24.8 1.0
OE1 A:GLU74 2.1 29.3 1.0
O2 A:OXL306 2.1 33.6 1.0
C1 A:OXL306 2.8 33.1 1.0
C2 A:OXL306 2.8 39.3 1.0
CD A:GLU76 3.1 18.4 1.0
CG A:ASP105 3.2 21.0 1.0
CD A:GLU74 3.3 31.5 1.0
OE1 A:GLU76 3.5 17.6 1.0
NZ A:LYS126 3.7 38.4 1.0
CB A:ASP105 3.8 21.0 1.0
OE2 A:GLU74 3.9 34.3 1.0
O3 A:OXL306 4.0 36.5 1.0
O4 A:OXL306 4.0 42.4 1.0
CZ A:PHE48 4.2 31.7 1.0
O A:VAL26 4.2 23.3 1.0
OD1 A:ASP105 4.2 18.4 1.0
CG A:GLU76 4.4 18.2 1.0
CG A:GLU74 4.4 29.7 1.0
CB A:GLU74 4.5 28.3 1.0
CA A:GLY194 4.5 23.8 1.0
N A:THR195 4.6 29.1 1.0
CB A:THR195 4.7 35.9 1.0
CE A:LYS126 4.7 33.5 1.0
CE1 A:PHE48 4.7 31.7 1.0
CG2 A:THR195 4.7 37.5 1.0
C A:GLY194 4.8 26.2 1.0

Magnesium binding site 2 out of 4 in 6sbi

Go back to Magnesium Binding Sites List in 6sbi
Magnesium binding site 2 out of 4 in the X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg301

b:22.5
occ:1.00
 O B:HOH405 1.8 7.3 1.0
OD2 B:ASP105 2.1 21.6 1.0
OE1 B:GLU74 2.1 22.0 1.0
OE2 B:GLU76 2.1 22.2 1.0
O4 B:OXL304 2.1 34.0 1.0
O3 B:OXL304 2.1 29.8 1.0
C1 B:OXL304 2.8 36.0 1.0
C2 B:OXL304 2.8 38.6 1.0
CD B:GLU76 3.1 22.3 1.0
CG B:ASP105 3.2 18.5 1.0
CD B:GLU74 3.3 23.1 1.0
OE1 B:GLU76 3.5 23.6 1.0
NZ B:LYS126 3.7 26.2 1.0
CB B:ASP105 3.8 16.6 1.0
OE2 B:GLU74 3.9 25.1 1.0
O1 B:OXL304 4.0 35.1 1.0
O2 B:OXL304 4.0 36.7 1.0
OD1 B:ASP105 4.2 18.1 1.0
CZ B:PHE48 4.3 28.3 1.0
O B:VAL26 4.3 21.8 1.0
CG B:GLU76 4.4 20.2 1.0
CG B:GLU74 4.4 21.0 1.0
CB B:GLU74 4.5 19.4 1.0
CA B:GLY194 4.5 29.5 1.0
N B:THR195 4.5 42.6 1.0
CB B:THR195 4.6 45.7 1.0
CG2 B:THR195 4.7 49.7 1.0
CE B:LYS126 4.7 26.6 1.0
CE1 B:PHE48 4.8 25.8 1.0
C B:GLY194 4.8 33.3 1.0

Magnesium binding site 3 out of 4 in 6sbi

Go back to Magnesium Binding Sites List in 6sbi
Magnesium binding site 3 out of 4 in the X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate within 5.0Å range:
probe atom residue distance (Å) B Occ
C:Mg301

b:28.3
occ:1.00
 O C:HOH401 2.1 7.9 1.0
OD2 C:ASP105 2.1 21.4 1.0
OE1 C:GLU74 2.1 31.1 1.0
O4 C:OXL306 2.1 42.7 1.0
OE2 C:GLU76 2.1 23.9 1.0
O3 C:OXL306 2.1 35.1 1.0
C1 C:OXL306 2.8 46.3 1.0
C2 C:OXL306 2.8 51.7 1.0
CD C:GLU76 3.1 22.3 1.0
CG C:ASP105 3.2 18.3 1.0
CD C:GLU74 3.3 31.5 1.0
OE1 C:GLU76 3.5 24.6 1.0
NZ C:LYS126 3.6 31.5 1.0
CB C:ASP105 3.8 18.0 1.0
OE2 C:GLU74 3.9 32.6 1.0
O1 C:OXL306 4.0 41.6 1.0
O2 C:OXL306 4.0 52.1 1.0
OD1 C:ASP105 4.2 16.9 1.0
CZ C:PHE48 4.2 25.9 1.0
O C:VAL26 4.3 25.6 1.0
CG C:GLU76 4.4 21.2 1.0
CG C:GLU74 4.4 28.9 1.0
CB C:GLU74 4.5 26.0 1.0
CA C:GLY194 4.5 25.1 1.0
N C:THR195 4.6 31.2 1.0
CE C:LYS126 4.6 35.1 1.0
CB C:THR195 4.7 34.1 1.0
CG2 C:THR195 4.7 34.6 1.0
CE1 C:PHE48 4.7 27.3 1.0
C C:GLY194 4.9 26.5 1.0

Magnesium binding site 4 out of 4 in 6sbi

Go back to Magnesium Binding Sites List in 6sbi
Magnesium binding site 4 out of 4 in the X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of X-Ray Structure of Murine Fumarylacetoacetate Hydrolase Domain Containing Protein 1 (FAHD1) in Complex with Inhibitor Oxalate within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mg301

b:24.2
occ:1.00
 O D:HOH403 1.9 13.0 1.0
OD2 D:ASP105 2.1 23.5 1.0
O2 D:OXL303 2.1 34.8 1.0
OE1 D:GLU74 2.1 26.8 1.0
O3 D:OXL303 2.1 37.1 1.0
OE2 D:GLU76 2.1 23.9 1.0
C2 D:OXL303 2.8 43.5 1.0
C1 D:OXL303 2.8 46.3 1.0
CD D:GLU76 3.2 22.6 1.0
CG D:ASP105 3.2 24.5 1.0
CD D:GLU74 3.3 24.2 1.0
OE1 D:GLU76 3.6 21.6 1.0
NZ D:LYS126 3.6 19.3 1.0
CB D:ASP105 3.8 24.6 1.0
OE2 D:GLU74 3.9 22.0 1.0
O4 D:OXL303 4.0 46.4 1.0
O1 D:OXL303 4.0 44.8 1.0
OD1 D:ASP105 4.2 21.9 1.0
CZ D:PHE48 4.2 30.1 1.0
O D:VAL26 4.3 19.5 1.0
CG D:GLU74 4.4 25.2 1.0
CG D:GLU76 4.4 22.5 1.0
CB D:GLU74 4.5 26.1 1.0
CA D:GLY194 4.6 22.8 1.0
N D:THR195 4.6 29.9 1.0
CE D:LYS126 4.6 19.5 1.0
CB D:THR195 4.7 29.8 1.0
CE1 D:PHE48 4.7 28.9 1.0
CG2 D:THR195 4.7 27.7 1.0
C D:GLY194 4.9 26.9 1.0

Reference:

A.K.H.Weiss, A.Naschberger, E.Cappuccio, C.Metzger, L.Mottes, M.Holzknecht, J.Von Velsen, M.W.Bowler, B.Rupp, P.Jansen-Durr. Structural and Functional Comparison of Fumarylacetoacetate Domain Containing Protein 1 in Human and Mouse. Biosci.Rep. V. 40 2020.
ISSN: ISSN 0144-8463
PubMed: 32068790
DOI: 10.1042/BSR20194431
Page generated: Tue Oct 1 17:50:39 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy