Magnesium in PDB 6t0s: Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence

All present enzymatic activity of Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence:
2.7.7.48;

The binding sites of Magnesium atom in the Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence (pdb code 6t0s). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence, PDB code: 6t0s:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg801 b:33.9 occ:1.00 O B:ASN306 2.3 28.8 1.0 C5' M:A38 2.8 45.7 1.0 OP1 M:A38 3.2 45.7 1.0 OD2 B:ASP445 3.4 34.3 1.0 OD1 B:ASP305 3.5 30.1 1.0 C B:ASN306 3.6 28.8 1.0 OD2 B:ASP305 3.8 30.1 1.0 O5' M:A38 3.8 45.7 1.0 C4' M:A38 3.9 45.7 1.0 CG B:ASP305 4.0 30.1 1.0 P M:A38 4.1 45.7 1.0 CA B:THR307 4.4 27.8 1.0 CG B:ASP445 4.4 34.3 1.0 O3' M:A38 4.4 45.7 1.0 N B:LYS308 4.4 29.9 1.0 N B:THR307 4.4 27.8 1.0 N B:ASN306 4.5 28.8 1.0 CA B:ASN306 4.6 28.8 1.0 C3' M:A38 4.6 45.7 1.0 C B:THR307 4.7 27.8 1.0 N B:TRP309 4.9 31.4 1.0

Magnesium binding site 2 out of 2 in the Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Bat Influenza A Polymerase Stuttering Complex Using 44-Mer Vrna Template with Intact Oligo(U) Sequence within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg802 b:30.5 occ:1.00 OD1 B:ASP446 2.1 30.8 1.0 OD2 B:ASP446 2.5 30.8 1.0 CG B:ASP446 2.6 30.8 1.0 O B:GLY304 3.5 27.0 1.0 OE1 B:GLU491 3.6 29.6 1.0 C B:GLY304 4.0 27.0 1.0 CB B:ASP446 4.1 30.8 1.0 OE2 B:GLU491 4.1 29.6 1.0 CG2 B:THR303 4.1 25.2 1.0 CD B:GLU491 4.2 29.6 1.0 N B:ASP305 4.3 30.1 1.0 O B:GLU491 4.4 29.6 1.0 CB B:ASP305 4.4 30.1 1.0 N B:GLY304 4.5 27.0 1.0 CA B:ASP305 4.5 30.1 1.0 O B:PHE447 4.6 27.7 1.0 CA B:ASP446 4.7 30.8 1.0 N B:PHE447 4.8 27.7 1.0 CA B:GLY304 4.8 27.0 1.0 N B:THR493 4.8 30.5 1.0 CG B:ASP305 4.9 30.1 1.0 CA B:PHE492 5.0 29.5 1.0

J.M.Wandzik, T.Kouba, M.Karuppasamy, A.Pflug, P.Drncova, J.Provaznik, N.Azevedo, S.Cusack. A Structure-Based Model For the Complete Transcription Cycle of Influenza Polymerase Cell(Cambridge,Mass.) 2020.
ISSN: ISSN 0092-8674