Magnesium in PDB 6t23: Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
(pdb code 6t23). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the
Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged), PDB code: 6t23:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
Magnesium binding site 1 out
of 5 in 6t23
Go back to
Magnesium Binding Sites List in 6t23
Magnesium binding site 1 out
of 5 in the Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg378
b:15.9
occ:1.00
|
O3
|
A:PO4377
|
2.1
|
15.8
|
1.0
|
OE1
|
A:GLN137
|
2.3
|
17.8
|
1.0
|
O2B
|
A:ADP376
|
2.3
|
18.1
|
1.0
|
CD
|
A:GLN137
|
3.5
|
16.8
|
1.0
|
P
|
A:PO4377
|
3.6
|
14.4
|
1.0
|
PB
|
A:ADP376
|
3.6
|
13.4
|
1.0
|
OD2
|
A:ASP154
|
3.8
|
14.9
|
1.0
|
O3B
|
A:ADP376
|
3.9
|
13.7
|
1.0
|
OD2
|
A:ASP11
|
4.0
|
18.7
|
1.0
|
OD1
|
A:ASP154
|
4.1
|
13.8
|
1.0
|
O4
|
A:PO4377
|
4.1
|
13.2
|
1.0
|
O2
|
A:PO4377
|
4.2
|
15.1
|
1.0
|
NE2
|
A:GLN137
|
4.2
|
18.1
|
1.0
|
OD1
|
A:ASP11
|
4.3
|
21.3
|
1.0
|
CG
|
A:ASP154
|
4.4
|
13.9
|
1.0
|
O1
|
A:PO4377
|
4.5
|
14.2
|
1.0
|
O1B
|
A:ADP376
|
4.5
|
14.5
|
1.0
|
O2A
|
A:ADP376
|
4.5
|
13.0
|
1.0
|
CG
|
A:ASP11
|
4.6
|
20.0
|
1.0
|
O3A
|
A:ADP376
|
4.6
|
12.0
|
1.0
|
CG
|
A:GLN137
|
4.7
|
16.4
|
1.0
|
CA
|
A:GLY156
|
4.8
|
10.7
|
1.0
|
NZ
|
A:LYS18
|
4.9
|
15.1
|
1.0
|
PA
|
A:ADP376
|
5.0
|
10.7
|
1.0
|
|
Magnesium binding site 2 out
of 5 in 6t23
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Magnesium Binding Sites List in 6t23
Magnesium binding site 2 out
of 5 in the Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg378
b:15.9
occ:1.00
|
O3
|
B:PO4377
|
2.1
|
15.8
|
1.0
|
OE1
|
B:GLN137
|
2.3
|
17.8
|
1.0
|
O2B
|
B:ADP376
|
2.3
|
18.1
|
1.0
|
CD
|
B:GLN137
|
3.5
|
16.8
|
1.0
|
P
|
B:PO4377
|
3.6
|
14.4
|
1.0
|
PB
|
B:ADP376
|
3.6
|
13.4
|
1.0
|
OD2
|
B:ASP154
|
3.8
|
14.9
|
1.0
|
O3B
|
B:ADP376
|
3.9
|
13.7
|
1.0
|
OD2
|
B:ASP11
|
4.0
|
18.7
|
1.0
|
OD1
|
B:ASP154
|
4.1
|
13.8
|
1.0
|
O4
|
B:PO4377
|
4.1
|
13.2
|
1.0
|
O2
|
B:PO4377
|
4.2
|
15.1
|
1.0
|
NE2
|
B:GLN137
|
4.2
|
18.1
|
1.0
|
OD1
|
B:ASP11
|
4.3
|
21.3
|
1.0
|
CG
|
B:ASP154
|
4.4
|
13.9
|
1.0
|
O1
|
B:PO4377
|
4.5
|
14.2
|
1.0
|
O1B
|
B:ADP376
|
4.5
|
14.5
|
1.0
|
O2A
|
B:ADP376
|
4.5
|
13.0
|
1.0
|
CG
|
B:ASP11
|
4.6
|
20.0
|
1.0
|
O3A
|
B:ADP376
|
4.6
|
12.0
|
1.0
|
CG
|
B:GLN137
|
4.7
|
16.4
|
1.0
|
CA
|
B:GLY156
|
4.8
|
10.7
|
1.0
|
NZ
|
B:LYS18
|
4.9
|
15.1
|
1.0
|
PA
|
B:ADP376
|
5.0
|
10.7
|
1.0
|
|
Magnesium binding site 3 out
of 5 in 6t23
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Magnesium Binding Sites List in 6t23
Magnesium binding site 3 out
of 5 in the Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg378
b:15.9
occ:1.00
|
O3
|
C:PO4377
|
2.1
|
15.8
|
1.0
|
OE1
|
C:GLN137
|
2.3
|
17.8
|
1.0
|
O2B
|
C:ADP376
|
2.3
|
18.1
|
1.0
|
CD
|
C:GLN137
|
3.5
|
16.8
|
1.0
|
P
|
C:PO4377
|
3.6
|
14.4
|
1.0
|
PB
|
C:ADP376
|
3.6
|
13.4
|
1.0
|
OD2
|
C:ASP154
|
3.8
|
14.9
|
1.0
|
O3B
|
C:ADP376
|
3.9
|
13.7
|
1.0
|
OD2
|
C:ASP11
|
4.0
|
18.7
|
1.0
|
OD1
|
C:ASP154
|
4.1
|
13.8
|
1.0
|
O4
|
C:PO4377
|
4.1
|
13.2
|
1.0
|
O2
|
C:PO4377
|
4.2
|
15.1
|
1.0
|
NE2
|
C:GLN137
|
4.2
|
18.1
|
1.0
|
OD1
|
C:ASP11
|
4.3
|
21.3
|
1.0
|
CG
|
C:ASP154
|
4.4
|
13.9
|
1.0
|
O1
|
C:PO4377
|
4.5
|
14.2
|
1.0
|
O1B
|
C:ADP376
|
4.5
|
14.5
|
1.0
|
O2A
|
C:ADP376
|
4.5
|
13.0
|
1.0
|
CG
|
C:ASP11
|
4.6
|
20.0
|
1.0
|
O3A
|
C:ADP376
|
4.6
|
12.0
|
1.0
|
CG
|
C:GLN137
|
4.7
|
16.4
|
1.0
|
CA
|
C:GLY156
|
4.8
|
10.7
|
1.0
|
NZ
|
C:LYS18
|
4.9
|
15.1
|
1.0
|
PA
|
C:ADP376
|
5.0
|
10.7
|
1.0
|
|
Magnesium binding site 4 out
of 5 in 6t23
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Magnesium Binding Sites List in 6t23
Magnesium binding site 4 out
of 5 in the Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg378
b:15.9
occ:1.00
|
O3
|
D:PO4377
|
2.1
|
15.8
|
1.0
|
OE1
|
D:GLN137
|
2.3
|
17.8
|
1.0
|
O2B
|
D:ADP376
|
2.3
|
18.1
|
1.0
|
CD
|
D:GLN137
|
3.5
|
16.8
|
1.0
|
P
|
D:PO4377
|
3.6
|
14.4
|
1.0
|
PB
|
D:ADP376
|
3.6
|
13.4
|
1.0
|
OD2
|
D:ASP154
|
3.8
|
14.9
|
1.0
|
O3B
|
D:ADP376
|
3.9
|
13.7
|
1.0
|
OD2
|
D:ASP11
|
4.0
|
18.7
|
1.0
|
OD1
|
D:ASP154
|
4.1
|
13.8
|
1.0
|
O4
|
D:PO4377
|
4.1
|
13.2
|
1.0
|
O2
|
D:PO4377
|
4.2
|
15.1
|
1.0
|
NE2
|
D:GLN137
|
4.2
|
18.1
|
1.0
|
OD1
|
D:ASP11
|
4.3
|
21.3
|
1.0
|
CG
|
D:ASP154
|
4.4
|
13.9
|
1.0
|
O1
|
D:PO4377
|
4.5
|
14.2
|
1.0
|
O1B
|
D:ADP376
|
4.5
|
14.5
|
1.0
|
O2A
|
D:ADP376
|
4.5
|
13.0
|
1.0
|
CG
|
D:ASP11
|
4.6
|
20.0
|
1.0
|
O3A
|
D:ADP376
|
4.6
|
12.0
|
1.0
|
CG
|
D:GLN137
|
4.7
|
16.4
|
1.0
|
CA
|
D:GLY156
|
4.8
|
10.7
|
1.0
|
NZ
|
D:LYS18
|
4.9
|
15.1
|
1.0
|
PA
|
D:ADP376
|
5.0
|
10.7
|
1.0
|
|
Magnesium binding site 5 out
of 5 in 6t23
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Magnesium Binding Sites List in 6t23
Magnesium binding site 5 out
of 5 in the Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged)
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Cryo-Em Structure of Jasplakinolide-Stabilized F-Actin (Aged) within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
E:Mg378
b:15.9
occ:1.00
|
O3
|
E:PO4377
|
2.1
|
15.8
|
1.0
|
OE1
|
E:GLN137
|
2.3
|
17.8
|
1.0
|
O2B
|
E:ADP376
|
2.3
|
18.1
|
1.0
|
CD
|
E:GLN137
|
3.5
|
16.8
|
1.0
|
P
|
E:PO4377
|
3.6
|
14.4
|
1.0
|
PB
|
E:ADP376
|
3.6
|
13.4
|
1.0
|
OD2
|
E:ASP154
|
3.8
|
14.9
|
1.0
|
O3B
|
E:ADP376
|
3.9
|
13.7
|
1.0
|
OD2
|
E:ASP11
|
4.0
|
18.7
|
1.0
|
OD1
|
E:ASP154
|
4.1
|
13.8
|
1.0
|
O4
|
E:PO4377
|
4.1
|
13.2
|
1.0
|
O2
|
E:PO4377
|
4.2
|
15.1
|
1.0
|
NE2
|
E:GLN137
|
4.2
|
18.1
|
1.0
|
OD1
|
E:ASP11
|
4.3
|
21.3
|
1.0
|
CG
|
E:ASP154
|
4.4
|
13.9
|
1.0
|
O1
|
E:PO4377
|
4.5
|
14.2
|
1.0
|
O1B
|
E:ADP376
|
4.5
|
14.5
|
1.0
|
O2A
|
E:ADP376
|
4.5
|
13.0
|
1.0
|
CG
|
E:ASP11
|
4.6
|
20.0
|
1.0
|
O3A
|
E:ADP376
|
4.6
|
12.0
|
1.0
|
CG
|
E:GLN137
|
4.7
|
16.4
|
1.0
|
CA
|
E:GLY156
|
4.8
|
10.7
|
1.0
|
NZ
|
E:LYS18
|
4.9
|
15.1
|
1.0
|
PA
|
E:ADP376
|
5.0
|
10.7
|
1.0
|
|
Reference:
S.Pospich,
F.Merino,
S.Raunser.
Structural Effects and Functional Implications of Phalloidin and Jasplakinolide Binding to Actin Filaments. Structure 2020.
ISSN: ISSN 0969-2126
PubMed: 32084355
DOI: 10.1016/J.STR.2020.01.014
Page generated: Tue Oct 1 18:35:25 2024
|