Magnesium in PDB 6tsk: Beta-Galactosidase in Complex with L-Ribose

The binding sites of Magnesium atom in the Beta-Galactosidase in Complex with L-Ribose (pdb code 6tsk). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Beta-Galactosidase in Complex with L-Ribose, PDB code: 6tsk:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Beta-Galactosidase in Complex with L-Ribose


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Beta-Galactosidase in Complex with L-Ribose within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg3001 b:3.9 occ:1.00 OE2 A:GLU416 2.1 11.8 1.0 O A:HOH3136 2.2 1.5 1.0 O A:HOH3208 2.3 1.1 1.0 OE1 A:GLU461 2.4 22.0 1.0 ND1 A:HIS418 2.4 9.3 1.0 O A:HOH3114 2.4 0.5 1.0 CE1 A:HIS418 3.3 10.2 1.0 CD A:GLU416 3.3 11.0 1.0 CD A:GLU461 3.3 31.7 1.0 CG A:HIS418 3.4 9.4 1.0 CB A:HIS418 3.7 6.4 1.0 OE1 A:GLU416 3.8 12.5 1.0 OE2 A:GLU461 4.0 43.4 1.0 OD1 A:ASN102 4.2 11.1 1.0 O A:ASP199 4.3 4.9 1.0 CB A:ASP201 4.3 10.3 1.0 CG A:GLU461 4.4 23.6 1.0 O2 A:0MK3002 4.4 14.9 1.0 CB A:GLU461 4.4 12.2 1.0 N A:ASP201 4.4 9.3 1.0 O3 A:0MK3002 4.5 12.1 1.0 NE2 A:HIS418 4.5 11.1 1.0 CG A:GLU416 4.5 8.2 1.0 CD2 A:HIS418 4.5 9.0 1.0 ND2 A:ASN460 4.5 11.8 1.0 C1 A:0MK3002 4.7 18.2 1.0 O A:ASN102 4.8 8.9 1.0 O1 A:0MK3002 4.8 16.9 1.0 CA A:ASP201 5.0 9.7 1.0

Magnesium binding site 2 out of 4 in the Beta-Galactosidase in Complex with L-Ribose


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Beta-Galactosidase in Complex with L-Ribose within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg3001 b:3.9 occ:1.00 OE2 B:GLU416 2.1 11.8 1.0 O B:HOH3136 2.2 1.5 1.0 O B:HOH3208 2.3 1.1 1.0 OE1 B:GLU461 2.4 22.0 1.0 ND1 B:HIS418 2.4 9.3 1.0 O B:HOH3114 2.4 0.5 1.0 CE1 B:HIS418 3.3 10.2 1.0 CD B:GLU416 3.3 11.0 1.0 CD B:GLU461 3.3 31.7 1.0 CG B:HIS418 3.4 9.4 1.0 CB B:HIS418 3.7 6.4 1.0 OE1 B:GLU416 3.8 12.5 1.0 OE2 B:GLU461 4.0 43.4 1.0 OD1 B:ASN102 4.2 11.1 1.0 O B:ASP199 4.3 4.9 1.0 CB B:ASP201 4.3 10.3 1.0 CG B:GLU461 4.4 23.6 1.0 O2 B:0MK3002 4.4 14.9 1.0 CB B:GLU461 4.4 12.2 1.0 N B:ASP201 4.4 9.3 1.0 O3 B:0MK3002 4.5 12.1 1.0 NE2 B:HIS418 4.5 11.1 1.0 CG B:GLU416 4.5 8.2 1.0 CD2 B:HIS418 4.5 9.0 1.0 ND2 B:ASN460 4.5 11.8 1.0 C1 B:0MK3002 4.7 18.2 1.0 O B:ASN102 4.8 8.9 1.0 O1 B:0MK3002 4.8 16.9 1.0 CA B:ASP201 5.0 9.7 1.0

Magnesium binding site 3 out of 4 in the Beta-Galactosidase in Complex with L-Ribose


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Beta-Galactosidase in Complex with L-Ribose within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg3001 b:3.9 occ:1.00 OE2 C:GLU416 2.1 11.8 1.0 O C:HOH3136 2.2 1.5 1.0 O C:HOH3208 2.3 1.1 1.0 OE1 C:GLU461 2.4 22.0 1.0 ND1 C:HIS418 2.4 9.3 1.0 O C:HOH3114 2.4 0.5 1.0 CE1 C:HIS418 3.3 10.2 1.0 CD C:GLU416 3.3 11.0 1.0 CD C:GLU461 3.3 31.7 1.0 CG C:HIS418 3.4 9.4 1.0 CB C:HIS418 3.7 6.4 1.0 OE1 C:GLU416 3.8 12.5 1.0 OE2 C:GLU461 4.0 43.4 1.0 OD1 C:ASN102 4.2 11.1 1.0 O C:ASP199 4.3 4.9 1.0 CB C:ASP201 4.4 10.3 1.0 CG C:GLU461 4.4 23.6 1.0 O2 C:0MK3002 4.4 14.9 1.0 CB C:GLU461 4.4 12.2 1.0 N C:ASP201 4.4 9.3 1.0 O3 C:0MK3002 4.5 12.1 1.0 NE2 C:HIS418 4.5 11.1 1.0 CG C:GLU416 4.5 8.2 1.0 CD2 C:HIS418 4.5 9.0 1.0 ND2 C:ASN460 4.5 11.8 1.0 C1 C:0MK3002 4.7 18.2 1.0 O C:ASN102 4.8 8.9 1.0 O1 C:0MK3002 4.8 16.9 1.0 CA C:ASP201 5.0 9.7 1.0

Magnesium binding site 4 out of 4 in the Beta-Galactosidase in Complex with L-Ribose


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Beta-Galactosidase in Complex with L-Ribose within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg3001 b:3.9 occ:1.00 OE2 D:GLU416 2.1 11.8 1.0 O D:HOH3135 2.2 1.5 1.0 O D:HOH3208 2.3 1.1 1.0 OE1 D:GLU461 2.4 22.0 1.0 ND1 D:HIS418 2.4 9.3 1.0 O D:HOH3114 2.4 0.5 1.0 CE1 D:HIS418 3.3 10.2 1.0 CD D:GLU416 3.3 11.0 1.0 CD D:GLU461 3.3 31.7 1.0 CG D:HIS418 3.4 9.4 1.0 CB D:HIS418 3.7 6.4 1.0 OE1 D:GLU416 3.8 12.5 1.0 OE2 D:GLU461 4.0 43.4 1.0 OD1 D:ASN102 4.2 11.1 1.0 O D:ASP199 4.3 4.9 1.0 CB D:ASP201 4.3 10.3 1.0 CG D:GLU461 4.4 23.6 1.0 O2 D:0MK3002 4.4 14.9 1.0 CB D:GLU461 4.4 12.2 1.0 N D:ASP201 4.4 9.3 1.0 O3 D:0MK3002 4.5 12.1 1.0 NE2 D:HIS418 4.5 11.1 1.0 CG D:GLU416 4.5 8.2 1.0 CD2 D:HIS418 4.5 9.0 1.0 ND2 D:ASN460 4.5 11.8 1.0 C1 D:0MK3002 4.7 18.2 1.0 O D:ASN102 4.8 8.9 1.0 O1 D:0MK3002 4.8 16.9 1.0 CA D:ASP201 5.0 9.7 1.0

M.Saur, M.J.Hartshorn, J.Dong, J.Reeks, G.Bunkoczi, H.Jhoti, P.A.Williams. Fragment-Based Drug Discovery Using Cryo-Em Drug Discov Today 2019.
ISSN: ESSN 1878-5832
PubMed: 31877353
DOI: 10.1016/J.DRUDIS.2019.12.006