Magnesium in PDB 6ugf: Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate

All present enzymatic activity of Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate:
5.6.1.1;

The binding sites of Magnesium atom in the Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate (pdb code 6ugf). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate, PDB code: 6ugf:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg502 b:30.0 occ:1.00 O2G B:ATP501 2.1 5.6 1.0 O2B B:ATP501 2.1 5.6 1.0 O2A B:ATP501 2.1 5.6 1.0 O3B B:ATP501 2.1 5.6 1.0 PG B:ATP501 2.5 5.6 1.0 PB B:ATP501 2.5 5.6 1.0 PA B:ATP501 3.0 5.6 1.0 O3G B:ATP501 3.0 5.6 1.0 CG2 B:THR240 3.1 0.0 1.0 O3A B:ATP501 3.2 5.6 1.0 NH2 C:ARG352 3.3 20.0 1.0 O1A B:ATP501 3.6 5.6 1.0 OG1 B:THR240 3.8 0.0 1.0 O1G B:ATP501 3.8 5.6 1.0 O1B B:ATP501 3.9 5.6 1.0 CB B:THR240 4.1 0.0 1.0 N B:THR240 4.2 0.0 1.0 O5' B:ATP501 4.4 5.6 1.0 CZ C:ARG352 4.6 20.0 1.0 N B:LYS239 4.8 0.5 1.0 CA B:THR240 4.8 0.0 1.0 NZ B:LYS239 4.9 30.0 1.0

Magnesium binding site 2 out of 4 in the Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg502 b:30.0 occ:1.00 O3B C:ATP501 2.1 4.0 1.0 O2G C:ATP501 2.1 4.0 1.0 PG C:ATP501 2.5 4.0 1.0 OG1 C:THR240 2.5 0.4 1.0 O1G C:ATP501 3.0 4.0 1.0 PB C:ATP501 3.5 4.0 1.0 NH2 D:ARG352 3.6 95.3 1.0 O3A C:ATP501 3.8 4.0 1.0 O3G C:ATP501 3.9 4.0 1.0 CB C:THR240 3.9 0.4 1.0 NE2 C:GLN293 4.0 0.2 1.0 O1B C:ATP501 4.3 4.0 1.0 CG2 C:THR240 4.3 0.4 1.0 O2B C:ATP501 4.4 4.0 1.0 CZ D:ARG352 4.5 95.3 1.0 NH1 D:ARG352 4.5 95.3 1.0 N C:THR240 4.9 0.4 1.0 CA C:THR240 4.9 0.4 1.0 OD1 D:ASP322 5.0 0.8 1.0 OD1 C:ASP292 5.0 0.4 1.0

Magnesium binding site 3 out of 4 in the Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg502 b:30.0 occ:1.00 O3G D:ATP501 2.1 4.0 1.0 O2B D:ATP501 2.1 4.0 1.0 CG2 D:THR240 2.7 88.1 1.0 PB D:ATP501 3.3 4.0 1.0 PG D:ATP501 3.3 4.0 1.0 O3B D:ATP501 3.6 4.0 1.0 NH2 E:ARG352 3.7 0.6 1.0 CB D:THR240 3.9 88.1 1.0 OG1 D:THR240 4.0 88.1 1.0 O1G D:ATP501 4.1 4.0 1.0 NE2 D:GLN293 4.1 95.6 1.0 O1B D:ATP501 4.2 4.0 1.0 O2G D:ATP501 4.5 4.0 1.0 OD2 D:ASP292 4.5 89.4 1.0 N D:THR240 4.5 88.1 1.0 O3A D:ATP501 4.6 4.0 1.0 O2A D:ATP501 4.7 4.0 1.0 OD1 D:ASP292 4.7 89.4 1.0 O1A D:ATP501 4.8 4.0 1.0 CA D:THR240 4.9 88.1 1.0 PA D:ATP501 4.9 4.0 1.0 CZ E:ARG352 5.0 0.6 1.0

Magnesium binding site 4 out of 4 in the Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Katanin Hexamer in the Ring Conformation with Resolved Protomer One in Complex with Substrate within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg502 b:30.0 occ:1.00 O1G E:ATP501 2.0 4.0 1.0 O2B E:ATP501 2.1 4.0 1.0 O3G E:ATP501 2.2 4.0 1.0 PG E:ATP501 2.5 4.0 1.0 OG1 E:THR240 2.8 88.8 1.0 PB E:ATP501 3.0 4.0 1.0 O3B E:ATP501 3.2 4.0 1.0 NH1 F:ARG352 3.4 30.0 1.0 O1B E:ATP501 3.6 4.0 1.0 O2G E:ATP501 3.9 4.0 1.0 CB E:THR240 4.2 88.8 1.0 NE2 E:GLN293 4.3 0.0 1.0 NH2 F:ARG351 4.4 30.0 1.0 O3A E:ATP501 4.4 4.0 1.0 CZ F:ARG352 4.5 30.0 1.0 CG2 E:THR240 4.8 88.8 1.0 N E:THR240 4.9 88.8 1.0 O2A E:ATP501 4.9 4.0 1.0

E.A.Zehr, A.Szyk, E.Szczesna, A.Roll-Mecak. Katanin Grips the Beta-Tubulin Tail Through An Electropositive Double Spiral to Sever Microtubules. Dev.Cell 2019.
ISSN: ISSN 1534-5807
PubMed: 31735665
DOI: 10.1016/J.DEVCEL.2019.10.010