Magnesium in PDB 6usq: Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna

All present enzymatic activity of Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna:
2.7.7.49;

The structure of Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna, PDB code: 6usq was solved by M.A.Schaich, B.D.Freudenthal, T.H.Khoang, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.90 / 3.62
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	101.009, 101.009, 379.086, 90.00, 90.00, 120.00
R / Rfree (%)	28.1 / 29.7

The binding sites of Magnesium atom in the Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna (pdb code 6usq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna, PDB code: 6usq:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg101 b:0.8 occ:1.00 OP1 F:U2 3.1 0.1 1.0 OP2 F:G3 3.1 0.8 1.0 O5' F:U2 3.4 0.3 1.0 P F:U2 3.6 0.7 1.0 OP1 F:G3 3.7 0.4 1.0 P F:G3 3.8 0.5 1.0 OP2 F:U2 3.8 0.5 1.0 C5' F:U2 4.0 0.6 1.0 O3' F:U2 4.2 0.2 1.0 C3' F:U2 4.5 0.5 1.0 C4' F:U2 4.8 0.8 1.0

Magnesium binding site 2 out of 2 in the Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg102 b:0.1 occ:1.00 OP1 F:G3 3.0 0.4 1.0 O5' F:G3 3.4 0.9 1.0 OP2 F:A4 3.5 0.8 1.0 P F:G3 3.6 0.5 1.0 C5' F:G3 3.7 0.2 1.0 OP2 F:G3 4.2 0.8 1.0 P F:A4 4.3 0.1 1.0 OP1 F:A4 4.5 0.7 1.0 O3' F:G3 4.5 0.6 1.0 CE A:LYS210 4.6 0.9 1.0 CG A:LYS210 4.6 0.1 1.0 C3' F:G3 4.7 0.8 1.0 CD A:LYS210 4.7 0.6 1.0 C4' F:G3 4.7 0.1 1.0

M.A.Schaich, S.L.Sanford, G.Welfer, T.H.Khoang, S.A.Johnson, P.L.Opresko, B.D.Freudenthal. Telomerase Reverse Transcriptase Binary Complex with Y256A Mutation, Tert:Dna To Be Published.