Magnesium in PDB 6v6f: Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex

The structure of Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex, PDB code: 6v6f was solved by W.Yan, D.K.Simanshu, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	78.32 / 2.54
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	72.011, 70.240, 79.700, 90.00, 100.67, 90.00
R / Rfree (%)	21.6 / 26.5

The structure of Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Magnesium atom in the Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex (pdb code 6v6f). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex, PDB code: 6v6f:

Magnesium binding site 1 out of 1 in the Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Q61L Kras(Gmppnp)-NF1(Grd)-SPRED1(EVH1) Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg502 b:64.6 occ:1.00 O C:HOH604 1.9 42.7 0.6 O C:HOH603 1.9 47.2 0.8 O3G C:GNP501 2.0 57.9 1.0 OG C:SER17 2.1 59.0 1.0 OG1 C:THR35 2.2 83.3 1.0 O2B C:GNP501 2.2 42.7 1.0 CG2 C:THR35 2.9 78.8 1.0 CB C:THR35 3.0 58.4 1.0 CB C:SER17 3.2 37.8 1.0 PG C:GNP501 3.4 53.5 1.0 OD2 C:ASP57 3.6 74.2 1.0 PB C:GNP501 3.6 61.2 1.0 N C:THR35 3.7 55.0 1.0 N3B C:GNP501 3.9 51.3 1.0 CA C:THR35 4.0 59.8 1.0 N C:SER17 4.0 57.4 1.0 OD1 C:ASP57 4.1 72.7 1.0 O2G C:GNP501 4.1 64.0 1.0 CG C:ASP57 4.1 70.3 1.0 CA C:SER17 4.1 46.8 1.0 O2A C:GNP501 4.3 48.5 1.0 O C:ASP33 4.3 58.2 1.0 O C:THR58 4.3 55.7 1.0 O1G C:GNP501 4.4 49.8 1.0 O3A C:GNP501 4.5 61.6 1.0 O1B C:GNP501 4.6 52.5 1.0 C C:PRO34 4.7 56.2 1.0 PA C:GNP501 4.7 53.1 1.0 O1A C:GNP501 4.7 55.0 1.0 CB C:LYS16 4.9 44.6 1.0 CA C:PRO34 4.9 56.4 1.0 NZ B:LYS1436 4.9 65.1 1.0 C C:LYS16 4.9 58.9 1.0

W.Yan, E.Markegard, S.Dharmaiah, A.Urisman, M.Drew, D.Esposito, K.Scheffzek, D.V.Nissley, F.Mccormick, D.K.Simanshu. Structural Insights Into the SPRED1-Neurofibromin-Kras Complex and Disruption of SPRED1-Neurofibromin Interaction By Oncogenic Egfr. Cell Rep V. 32 07909 2020.
ISSN: ESSN 2211-1247
PubMed: 32697994
DOI: 10.1016/J.CELREP.2020.107909