Magnesium in PDB 6v6q: Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
Enzymatic activity of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
All present enzymatic activity of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657:
2.7.10.1;
Protein crystallography data
The structure of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657, PDB code: 6v6q
was solved by
C.-C.Lin,
L.Wieteska,
G.Poncet-Montange,
K.M.Suen,
S.T.Arold,
Z.Ahmed,
J.E.Ladbury,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Resolution Low / High (Å)
|
82.06 /
2.46
|
Space group
|
P 21 21 21
|
Cell size a, b, c (Å), α, β, γ (°)
|
63.970,
86.541,
254.162,
90.00,
90.00,
90.00
|
R / Rfree (%)
|
21.1 /
23.9
|
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
(pdb code 6v6q). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the
Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657, PDB code: 6v6q:
Jump to Magnesium binding site number:
1;
2;
3;
4;
Magnesium binding site 1 out
of 4 in 6v6q
Go back to
Magnesium Binding Sites List in 6v6q
Magnesium binding site 1 out
of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg902
b:53.0
occ:1.00
|
OD2
|
A:ASP644
|
2.1
|
64.2
|
1.0
|
O
|
A:HOH1016
|
2.4
|
56.8
|
1.0
|
O2G
|
A:ACP901
|
2.4
|
98.7
|
1.0
|
OD1
|
A:ASN631
|
2.8
|
45.0
|
1.0
|
O
|
A:HOH1001
|
2.9
|
40.6
|
1.0
|
O
|
A:HOH1002
|
3.1
|
40.1
|
1.0
|
CG
|
A:ASP644
|
3.1
|
62.4
|
1.0
|
O2B
|
A:ACP901
|
3.4
|
0.5
|
1.0
|
O3A
|
A:ACP901
|
3.4
|
0.8
|
1.0
|
OD1
|
A:ASP644
|
3.7
|
63.9
|
1.0
|
PG
|
A:ACP901
|
3.7
|
0.0
|
1.0
|
O
|
A:ARG630
|
3.8
|
47.5
|
1.0
|
PB
|
A:ACP901
|
3.9
|
0.7
|
1.0
|
CG
|
A:ASN631
|
4.0
|
47.2
|
1.0
|
O
|
A:HOH1012
|
4.1
|
76.5
|
1.0
|
O
|
A:HOH1017
|
4.2
|
58.2
|
1.0
|
C3B
|
A:ACP901
|
4.2
|
0.2
|
1.0
|
CB
|
A:ASP644
|
4.3
|
57.1
|
1.0
|
O1G
|
A:ACP901
|
4.4
|
0.6
|
1.0
|
O1A
|
A:ACP901
|
4.4
|
0.6
|
1.0
|
C
|
A:ARG630
|
4.6
|
50.1
|
1.0
|
PA
|
A:ACP901
|
4.6
|
0.5
|
1.0
|
CG
|
A:ARG630
|
4.7
|
56.1
|
1.0
|
CA
|
A:ASN631
|
4.8
|
48.5
|
1.0
|
O3G
|
A:ACP901
|
4.9
|
0.2
|
1.0
|
ND2
|
A:ASN631
|
4.9
|
45.8
|
1.0
|
N
|
A:ASN631
|
5.0
|
48.5
|
1.0
|
CB
|
A:ASN631
|
5.0
|
47.8
|
1.0
|
|
Magnesium binding site 2 out
of 4 in 6v6q
Go back to
Magnesium Binding Sites List in 6v6q
Magnesium binding site 2 out
of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg902
b:50.8
occ:1.00
|
OD2
|
B:ASP644
|
2.2
|
51.3
|
1.0
|
OD1
|
B:ASN631
|
2.4
|
31.4
|
1.0
|
O3G
|
B:ACP901
|
2.7
|
88.3
|
1.0
|
O
|
B:HOH1023
|
2.7
|
48.6
|
1.0
|
O2B
|
B:ACP901
|
2.9
|
95.0
|
1.0
|
O1G
|
B:ACP901
|
2.9
|
81.5
|
1.0
|
PG
|
B:ACP901
|
3.2
|
89.1
|
1.0
|
O
|
B:HOH1054
|
3.3
|
56.9
|
1.0
|
CG
|
B:ASP644
|
3.4
|
46.0
|
1.0
|
CG
|
B:ASN631
|
3.6
|
31.2
|
1.0
|
O
|
B:HOH1015
|
3.7
|
46.9
|
1.0
|
O
|
B:ARG630
|
3.7
|
35.2
|
1.0
|
C3B
|
B:ACP901
|
4.0
|
91.5
|
1.0
|
PB
|
B:ACP901
|
4.0
|
94.8
|
1.0
|
CG
|
B:ARG630
|
4.3
|
42.2
|
1.0
|
OD1
|
B:ASP644
|
4.3
|
51.8
|
1.0
|
CB
|
B:ASP644
|
4.3
|
38.5
|
1.0
|
ND2
|
B:ASN631
|
4.3
|
30.8
|
1.0
|
C
|
B:ARG630
|
4.4
|
33.4
|
1.0
|
CA
|
B:ASN631
|
4.6
|
30.7
|
1.0
|
O2G
|
B:ACP901
|
4.6
|
88.4
|
1.0
|
CB
|
B:ASN631
|
4.7
|
30.5
|
1.0
|
N
|
B:ASN631
|
4.7
|
30.6
|
1.0
|
CD
|
B:ARG630
|
4.8
|
48.8
|
1.0
|
CB
|
B:ARG630
|
5.0
|
38.3
|
1.0
|
NE
|
B:ARG630
|
5.0
|
54.7
|
1.0
|
|
Magnesium binding site 3 out
of 4 in 6v6q
Go back to
Magnesium Binding Sites List in 6v6q
Magnesium binding site 3 out
of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg902
b:72.5
occ:1.00
|
O1B
|
C:ACP901
|
2.1
|
0.7
|
1.0
|
OD2
|
C:ASP644
|
2.3
|
77.3
|
1.0
|
OD1
|
C:ASN631
|
2.4
|
52.7
|
1.0
|
O
|
C:HOH1019
|
3.2
|
70.4
|
1.0
|
CG
|
C:ASP644
|
3.5
|
75.0
|
1.0
|
O1A
|
C:ACP901
|
3.5
|
0.4
|
1.0
|
PB
|
C:ACP901
|
3.6
|
0.6
|
1.0
|
CG
|
C:ASN631
|
3.7
|
50.8
|
1.0
|
O
|
C:ARG630
|
3.8
|
54.0
|
1.0
|
O
|
C:HOH1001
|
3.9
|
57.6
|
1.0
|
CG
|
C:ARG630
|
4.0
|
59.0
|
1.0
|
O3A
|
C:ACP901
|
4.3
|
0.7
|
1.0
|
OD1
|
C:ASP644
|
4.3
|
77.8
|
1.0
|
C
|
C:ARG630
|
4.3
|
50.6
|
1.0
|
ND2
|
C:ASN631
|
4.4
|
50.4
|
1.0
|
CB
|
C:ASP644
|
4.4
|
72.1
|
1.0
|
PA
|
C:ACP901
|
4.5
|
0.3
|
1.0
|
C3B
|
C:ACP901
|
4.5
|
0.1
|
1.0
|
O2B
|
C:ACP901
|
4.5
|
0.8
|
1.0
|
CD
|
C:ARG630
|
4.6
|
62.4
|
1.0
|
CA
|
C:ASN631
|
4.6
|
48.9
|
1.0
|
N
|
C:ASN631
|
4.7
|
48.4
|
1.0
|
CB
|
C:ASN631
|
4.7
|
49.8
|
1.0
|
NE
|
C:ARG630
|
4.7
|
66.4
|
1.0
|
CB
|
C:ARG630
|
4.8
|
54.6
|
1.0
|
O5'
|
C:ACP901
|
4.9
|
0.9
|
1.0
|
|
Magnesium binding site 4 out
of 4 in 6v6q
Go back to
Magnesium Binding Sites List in 6v6q
Magnesium binding site 4 out
of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg902
b:0.5
occ:1.00
|
O2A
|
D:ACP901
|
1.8
|
0.6
|
1.0
|
OD2
|
D:ASP644
|
2.1
|
79.6
|
1.0
|
O1B
|
D:ACP901
|
2.1
|
0.9
|
1.0
|
O2G
|
D:ACP901
|
2.4
|
0.5
|
1.0
|
PA
|
D:ACP901
|
2.6
|
0.6
|
1.0
|
PB
|
D:ACP901
|
2.9
|
0.0
|
1.0
|
O
|
D:HOH1003
|
2.9
|
45.2
|
1.0
|
O
|
D:HOH1002
|
2.9
|
48.1
|
1.0
|
O3A
|
D:ACP901
|
2.9
|
0.6
|
1.0
|
CG
|
D:ASP644
|
2.9
|
76.6
|
1.0
|
O1A
|
D:ACP901
|
3.0
|
0.1
|
1.0
|
PG
|
D:ACP901
|
3.1
|
0.4
|
1.0
|
O3G
|
D:ACP901
|
3.2
|
0.4
|
1.0
|
OD1
|
D:ASP644
|
3.2
|
78.8
|
1.0
|
C3B
|
D:ACP901
|
3.4
|
0.7
|
1.0
|
O5'
|
D:ACP901
|
4.1
|
0.9
|
1.0
|
OD1
|
D:ASN631
|
4.1
|
61.0
|
1.0
|
CB
|
D:ASP644
|
4.3
|
72.1
|
1.0
|
O2B
|
D:ACP901
|
4.3
|
1.0
|
1.0
|
O1G
|
D:ACP901
|
4.5
|
0.5
|
1.0
|
NZ
|
D:LYS517
|
4.8
|
74.9
|
1.0
|
C5'
|
D:ACP901
|
4.9
|
0.8
|
1.0
|
|
Reference:
C.-C.Lin,
L.Wieteska,
G.Poncet-Montange,
K.M.Suen,
S.T.Arold,
Z.Ahmed,
J.E.Ladbury.
Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 To Be Published.
Page generated: Tue Oct 1 21:24:31 2024
|