Magnesium in PDB 6v6q: Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657

All present enzymatic activity of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657:
2.7.10.1;

The structure of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657, PDB code: 6v6q was solved by C.-C.Lin, L.Wieteska, G.Poncet-Montange, K.M.Suen, S.T.Arold, Z.Ahmed, J.E.Ladbury, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	82.06 / 2.46
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	63.970, 86.541, 254.162, 90.00, 90.00, 90.00
R / Rfree (%)	21.1 / 23.9

The binding sites of Magnesium atom in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 (pdb code 6v6q). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657, PDB code: 6v6q:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg902 b:53.0 occ:1.00 OD2 A:ASP644 2.1 64.2 1.0 O A:HOH1016 2.4 56.8 1.0 O2G A:ACP901 2.4 98.7 1.0 OD1 A:ASN631 2.8 45.0 1.0 O A:HOH1001 2.9 40.6 1.0 O A:HOH1002 3.1 40.1 1.0 CG A:ASP644 3.1 62.4 1.0 O2B A:ACP901 3.4 0.5 1.0 O3A A:ACP901 3.4 0.8 1.0 OD1 A:ASP644 3.7 63.9 1.0 PG A:ACP901 3.7 0.0 1.0 O A:ARG630 3.8 47.5 1.0 PB A:ACP901 3.9 0.7 1.0 CG A:ASN631 4.0 47.2 1.0 O A:HOH1012 4.1 76.5 1.0 O A:HOH1017 4.2 58.2 1.0 C3B A:ACP901 4.2 0.2 1.0 CB A:ASP644 4.3 57.1 1.0 O1G A:ACP901 4.4 0.6 1.0 O1A A:ACP901 4.4 0.6 1.0 C A:ARG630 4.6 50.1 1.0 PA A:ACP901 4.6 0.5 1.0 CG A:ARG630 4.7 56.1 1.0 CA A:ASN631 4.8 48.5 1.0 O3G A:ACP901 4.9 0.2 1.0 ND2 A:ASN631 4.9 45.8 1.0 N A:ASN631 5.0 48.5 1.0 CB A:ASN631 5.0 47.8 1.0

Magnesium binding site 2 out of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg902 b:50.8 occ:1.00 OD2 B:ASP644 2.2 51.3 1.0 OD1 B:ASN631 2.4 31.4 1.0 O3G B:ACP901 2.7 88.3 1.0 O B:HOH1023 2.7 48.6 1.0 O2B B:ACP901 2.9 95.0 1.0 O1G B:ACP901 2.9 81.5 1.0 PG B:ACP901 3.2 89.1 1.0 O B:HOH1054 3.3 56.9 1.0 CG B:ASP644 3.4 46.0 1.0 CG B:ASN631 3.6 31.2 1.0 O B:HOH1015 3.7 46.9 1.0 O B:ARG630 3.7 35.2 1.0 C3B B:ACP901 4.0 91.5 1.0 PB B:ACP901 4.0 94.8 1.0 CG B:ARG630 4.3 42.2 1.0 OD1 B:ASP644 4.3 51.8 1.0 CB B:ASP644 4.3 38.5 1.0 ND2 B:ASN631 4.3 30.8 1.0 C B:ARG630 4.4 33.4 1.0 CA B:ASN631 4.6 30.7 1.0 O2G B:ACP901 4.6 88.4 1.0 CB B:ASN631 4.7 30.5 1.0 N B:ASN631 4.7 30.6 1.0 CD B:ARG630 4.8 48.8 1.0 CB B:ARG630 5.0 38.3 1.0 NE B:ARG630 5.0 54.7 1.0

Magnesium binding site 3 out of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg902 b:72.5 occ:1.00 O1B C:ACP901 2.1 0.7 1.0 OD2 C:ASP644 2.3 77.3 1.0 OD1 C:ASN631 2.4 52.7 1.0 O C:HOH1019 3.2 70.4 1.0 CG C:ASP644 3.5 75.0 1.0 O1A C:ACP901 3.5 0.4 1.0 PB C:ACP901 3.6 0.6 1.0 CG C:ASN631 3.7 50.8 1.0 O C:ARG630 3.8 54.0 1.0 O C:HOH1001 3.9 57.6 1.0 CG C:ARG630 4.0 59.0 1.0 O3A C:ACP901 4.3 0.7 1.0 OD1 C:ASP644 4.3 77.8 1.0 C C:ARG630 4.3 50.6 1.0 ND2 C:ASN631 4.4 50.4 1.0 CB C:ASP644 4.4 72.1 1.0 PA C:ACP901 4.5 0.3 1.0 C3B C:ACP901 4.5 0.1 1.0 O2B C:ACP901 4.5 0.8 1.0 CD C:ARG630 4.6 62.4 1.0 CA C:ASN631 4.6 48.9 1.0 N C:ASN631 4.7 48.4 1.0 CB C:ASN631 4.7 49.8 1.0 NE C:ARG630 4.7 66.4 1.0 CB C:ARG630 4.8 54.6 1.0 O5' C:ACP901 4.9 0.9 1.0

Magnesium binding site 4 out of 4 in the Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg902 b:0.5 occ:1.00 O2A D:ACP901 1.8 0.6 1.0 OD2 D:ASP644 2.1 79.6 1.0 O1B D:ACP901 2.1 0.9 1.0 O2G D:ACP901 2.4 0.5 1.0 PA D:ACP901 2.6 0.6 1.0 PB D:ACP901 2.9 0.0 1.0 O D:HOH1003 2.9 45.2 1.0 O D:HOH1002 2.9 48.1 1.0 O3A D:ACP901 2.9 0.6 1.0 CG D:ASP644 2.9 76.6 1.0 O1A D:ACP901 3.0 0.1 1.0 PG D:ACP901 3.1 0.4 1.0 O3G D:ACP901 3.2 0.4 1.0 OD1 D:ASP644 3.2 78.8 1.0 C3B D:ACP901 3.4 0.7 1.0 O5' D:ACP901 4.1 0.9 1.0 OD1 D:ASN631 4.1 61.0 1.0 CB D:ASP644 4.3 72.1 1.0 O2B D:ACP901 4.3 1.0 1.0 O1G D:ACP901 4.5 0.5 1.0 NZ D:LYS517 4.8 74.9 1.0 C5' D:ACP901 4.9 0.8 1.0

C.-C.Lin, L.Wieteska, G.Poncet-Montange, K.M.Suen, S.T.Arold, Z.Ahmed, J.E.Ladbury. Crystal Structure of Monophosphorylated Fgf Receptor 2 Isoform Iiib with PTR657 To Be Published.