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Magnesium in PDB 6vvz: Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin

Enzymatic activity of Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin

All present enzymatic activity of Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin:
2.7.7.6;

Other elements in 6vvz:

The structure of Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin also contains other interesting chemical elements:

Zinc (Zn) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin (pdb code 6vvz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin, PDB code: 6vvz:

Magnesium binding site 1 out of 1 in 6vvz

Go back to Magnesium Binding Sites List in 6vvz
Magnesium binding site 1 out of 1 in the Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mycobacterium Tuberculosis Rnap S456L Mutant Transcription Initiation Intermediate Structure with Sorangicin within 5.0Å range:
probe atom residue distance (Å) B Occ
D:Mg2002

b:0.1
occ:1.00
OD1 D:ASP537 2.1 0.9 1.0
OD2 D:ASP539 2.2 0.2 1.0
OD1 D:ASP535 2.2 0.7 1.0
OD2 D:ASP537 2.2 0.9 1.0
OD1 D:ASP539 2.5 0.2 1.0
CG D:ASP537 2.5 0.9 1.0
CG D:ASP539 2.6 0.2 1.0
CG D:ASP535 3.0 0.7 1.0
OD2 D:ASP535 3.3 0.7 1.0
O D:ASP535 4.0 0.7 1.0
CB D:ASP537 4.0 0.9 1.0
CB D:ASP539 4.0 0.2 1.0
NH2 D:ARG500 4.1 1.0 1.0
CB D:ASP535 4.4 0.7 1.0
C D:ASP535 4.4 0.7 1.0
N D:ASP535 4.5 0.7 1.0
N D:ASP537 4.5 0.9 1.0
CA D:ASP535 4.7 0.7 1.0
CA D:ASP537 4.7 0.9 1.0
N D:ASP539 4.8 0.2 1.0
CA D:ASP539 4.9 0.2 1.0

Reference:

M.Lilic, J.Chen, H.Boyaci, N.Braffman, E.A.Hubin, J.Herrmann, R.Muller, R.Mooney, R.Landick, S.A.Darst, E.A.Campbell. The Antibiotic Sorangicin A Inhibits Promoter Dna Unwinding in A Mycobacterium Tuberculosis Rifampicin-Resistant Rna Polymerase. Proc.Natl.Acad.Sci.Usa 2020.
ISSN: ESSN 1091-6490
PubMed: 33199626
DOI: 10.1073/PNAS.2013706117
Page generated: Tue Oct 1 22:15:54 2024

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