Magnesium in PDB 6w4f: uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc
Magnesium Binding Sites:
The binding sites of Magnesium atom in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc
(pdb code 6w4f). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the
uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc, PDB code: 6w4f:
Jump to Magnesium binding site number:
1;
2;
Magnesium binding site 1 out
of 2 in 6w4f
Go back to
Magnesium Binding Sites List in 6w4f
Magnesium binding site 1 out
of 2 in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg202
b:10.0
occ:1.00
|
O3B
|
B:GDP201
|
1.3
|
10.0
|
1.0
|
OG
|
B:SER17
|
1.7
|
10.0
|
1.0
|
O
|
B:ASP33
|
1.8
|
10.0
|
1.0
|
HG
|
B:SER17
|
2.3
|
10.0
|
1.0
|
PB
|
B:GDP201
|
2.9
|
10.0
|
1.0
|
CB
|
B:SER17
|
2.9
|
10.0
|
1.0
|
C
|
B:ASP33
|
3.1
|
10.0
|
1.0
|
H
|
B:SER17
|
3.1
|
10.0
|
1.0
|
OD2
|
B:ASP12
|
3.4
|
10.0
|
1.0
|
OD2
|
B:ASP57
|
3.4
|
10.0
|
1.0
|
O1B
|
B:GDP201
|
3.6
|
10.0
|
1.0
|
HZ2
|
B:LYS16
|
3.7
|
10.0
|
1.0
|
O3A
|
B:GDP201
|
3.7
|
10.0
|
1.0
|
N
|
B:SER17
|
3.7
|
10.0
|
1.0
|
O2B
|
B:GDP201
|
3.8
|
10.0
|
1.0
|
H
|
B:ASP33
|
3.8
|
10.0
|
1.0
|
HZ3
|
B:LYS16
|
3.9
|
10.0
|
1.0
|
O1A
|
B:GDP201
|
3.9
|
10.0
|
1.0
|
CA
|
B:SER17
|
3.9
|
10.0
|
1.0
|
N
|
B:PRO34
|
3.9
|
10.0
|
1.0
|
CA
|
B:PRO34
|
4.0
|
10.0
|
1.0
|
CA
|
B:ASP33
|
4.1
|
10.0
|
1.0
|
NZ
|
B:LYS16
|
4.2
|
10.0
|
1.0
|
N
|
B:ASP33
|
4.4
|
10.0
|
1.0
|
CG
|
B:ASP57
|
4.4
|
10.0
|
1.0
|
PA
|
B:GDP201
|
4.4
|
10.0
|
1.0
|
CB
|
B:ASP33
|
4.5
|
10.0
|
1.0
|
H
|
B:THR35
|
4.5
|
10.0
|
1.0
|
CG
|
B:ASP12
|
4.6
|
10.0
|
1.0
|
OD1
|
B:ASP57
|
4.6
|
10.0
|
1.0
|
H
|
B:GLY13
|
4.6
|
10.0
|
1.0
|
CE
|
B:LYS16
|
4.6
|
10.0
|
1.0
|
H
|
B:LYS16
|
4.8
|
10.0
|
1.0
|
OD2
|
B:ASP33
|
4.8
|
10.0
|
1.0
|
O
|
B:ILE36
|
4.8
|
10.0
|
1.0
|
C
|
B:LYS16
|
4.9
|
10.0
|
1.0
|
CB
|
B:LYS16
|
4.9
|
10.0
|
1.0
|
C
|
B:PRO34
|
4.9
|
10.0
|
1.0
|
|
Magnesium binding site 2 out
of 2 in 6w4f
Go back to
Magnesium Binding Sites List in 6w4f
Magnesium binding site 2 out
of 2 in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg202
b:10.0
occ:1.00
|
O3B
|
C:GDP201
|
1.3
|
10.0
|
1.0
|
OD2
|
C:ASP57
|
1.6
|
10.0
|
1.0
|
OG
|
C:SER17
|
1.7
|
10.0
|
1.0
|
HG
|
C:SER17
|
2.4
|
10.0
|
1.0
|
H
|
C:SER17
|
2.5
|
10.0
|
1.0
|
CG
|
C:ASP57
|
2.8
|
10.0
|
1.0
|
PB
|
C:GDP201
|
2.9
|
10.0
|
1.0
|
CB
|
C:SER17
|
2.9
|
10.0
|
1.0
|
N
|
C:SER17
|
3.0
|
10.0
|
1.0
|
CA
|
C:SER17
|
3.3
|
10.0
|
1.0
|
OD1
|
C:ASP57
|
3.4
|
10.0
|
1.0
|
O2B
|
C:GDP201
|
3.5
|
10.0
|
1.0
|
HZ3
|
C:LYS16
|
3.6
|
10.0
|
1.0
|
O3A
|
C:GDP201
|
3.7
|
10.0
|
1.0
|
CB
|
C:LYS16
|
3.7
|
10.0
|
1.0
|
O1B
|
C:GDP201
|
3.8
|
10.0
|
1.0
|
C
|
C:LYS16
|
3.9
|
10.0
|
1.0
|
CB
|
C:ASP57
|
4.0
|
10.0
|
1.0
|
CE
|
C:LYS16
|
4.0
|
10.0
|
1.0
|
O
|
C:THR58
|
4.0
|
10.0
|
1.0
|
NZ
|
C:LYS16
|
4.1
|
10.0
|
1.0
|
HZ2
|
C:LYS16
|
4.1
|
10.0
|
1.0
|
CA
|
C:LYS16
|
4.3
|
10.0
|
1.0
|
H
|
C:LYS16
|
4.4
|
10.0
|
1.0
|
O2A
|
C:GDP201
|
4.5
|
10.0
|
1.0
|
N
|
C:LYS16
|
4.6
|
10.0
|
1.0
|
PA
|
C:GDP201
|
4.7
|
10.0
|
1.0
|
CG
|
C:LYS16
|
4.7
|
10.0
|
1.0
|
H
|
C:THR58
|
4.8
|
10.0
|
1.0
|
C
|
C:SER17
|
4.8
|
10.0
|
1.0
|
O
|
C:LYS16
|
4.8
|
10.0
|
1.0
|
CD
|
C:LYS16
|
4.9
|
10.0
|
1.0
|
H
|
C:ALA18
|
4.9
|
10.0
|
1.0
|
|
Reference:
K.Y.Lee,
Z.Fang,
M.Enomoto,
G.G.Seabrook,
L.Zheng,
S.Koide,
M.Ikura,
C.B.Marshall.
Two Distinct Structures of Membrane-Associated Homodimers of Gtp- and Gdp-Bound KRAS4B Revealed By Paramagnetic Relaxation Enhancement. Angew.Chem.Int.Ed.Engl. 2020.
ISSN: ESSN 1521-3773
PubMed: 32227412
DOI: 10.1002/ANIE.202001758
Page generated: Tue Dec 15 01:32:23 2020
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