Magnesium in PDB 6w4f: uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc

The binding sites of Magnesium atom in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc (pdb code 6w4f). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc, PDB code: 6w4f:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg202 b:10.0 occ:1.00 O3B B:GDP201 1.3 10.0 1.0 OG B:SER17 1.7 10.0 1.0 O B:ASP33 1.8 10.0 1.0 HG B:SER17 2.3 10.0 1.0 PB B:GDP201 2.9 10.0 1.0 CB B:SER17 2.9 10.0 1.0 C B:ASP33 3.1 10.0 1.0 H B:SER17 3.1 10.0 1.0 OD2 B:ASP12 3.4 10.0 1.0 OD2 B:ASP57 3.4 10.0 1.0 O1B B:GDP201 3.6 10.0 1.0 HZ2 B:LYS16 3.7 10.0 1.0 O3A B:GDP201 3.7 10.0 1.0 N B:SER17 3.7 10.0 1.0 O2B B:GDP201 3.8 10.0 1.0 H B:ASP33 3.8 10.0 1.0 HZ3 B:LYS16 3.9 10.0 1.0 O1A B:GDP201 3.9 10.0 1.0 CA B:SER17 3.9 10.0 1.0 N B:PRO34 3.9 10.0 1.0 CA B:PRO34 4.0 10.0 1.0 CA B:ASP33 4.1 10.0 1.0 NZ B:LYS16 4.2 10.0 1.0 N B:ASP33 4.4 10.0 1.0 CG B:ASP57 4.4 10.0 1.0 PA B:GDP201 4.4 10.0 1.0 CB B:ASP33 4.5 10.0 1.0 H B:THR35 4.5 10.0 1.0 CG B:ASP12 4.6 10.0 1.0 OD1 B:ASP57 4.6 10.0 1.0 H B:GLY13 4.6 10.0 1.0 CE B:LYS16 4.6 10.0 1.0 H B:LYS16 4.8 10.0 1.0 OD2 B:ASP33 4.8 10.0 1.0 O B:ILE36 4.8 10.0 1.0 C B:LYS16 4.9 10.0 1.0 CB B:LYS16 4.9 10.0 1.0 C B:PRO34 4.9 10.0 1.0

Magnesium binding site 2 out of 2 in the uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of uc(Nmr)-Driven Structure of KRAS4B-Gdp Homodimer on A Lipid Bilayer Nanodisc within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg202 b:10.0 occ:1.00 O3B C:GDP201 1.3 10.0 1.0 OD2 C:ASP57 1.6 10.0 1.0 OG C:SER17 1.7 10.0 1.0 HG C:SER17 2.4 10.0 1.0 H C:SER17 2.5 10.0 1.0 CG C:ASP57 2.8 10.0 1.0 PB C:GDP201 2.9 10.0 1.0 CB C:SER17 2.9 10.0 1.0 N C:SER17 3.0 10.0 1.0 CA C:SER17 3.3 10.0 1.0 OD1 C:ASP57 3.4 10.0 1.0 O2B C:GDP201 3.5 10.0 1.0 HZ3 C:LYS16 3.6 10.0 1.0 O3A C:GDP201 3.7 10.0 1.0 CB C:LYS16 3.7 10.0 1.0 O1B C:GDP201 3.8 10.0 1.0 C C:LYS16 3.9 10.0 1.0 CB C:ASP57 4.0 10.0 1.0 CE C:LYS16 4.0 10.0 1.0 O C:THR58 4.0 10.0 1.0 NZ C:LYS16 4.1 10.0 1.0 HZ2 C:LYS16 4.1 10.0 1.0 CA C:LYS16 4.3 10.0 1.0 H C:LYS16 4.4 10.0 1.0 O2A C:GDP201 4.5 10.0 1.0 N C:LYS16 4.6 10.0 1.0 PA C:GDP201 4.7 10.0 1.0 CG C:LYS16 4.7 10.0 1.0 H C:THR58 4.8 10.0 1.0 C C:SER17 4.8 10.0 1.0 O C:LYS16 4.8 10.0 1.0 CD C:LYS16 4.9 10.0 1.0 H C:ALA18 4.9 10.0 1.0

K.Y.Lee, Z.Fang, M.Enomoto, G.G.Seabrook, L.Zheng, S.Koide, M.Ikura, C.B.Marshall. Two Distinct Structures of Membrane-Associated Homodimers of Gtp- and Gdp-Bound KRAS4B Revealed By Paramagnetic Relaxation Enhancement. Angew.Chem.Int.Ed.Engl. 2020.
ISSN: ESSN 1521-3773
PubMed: 32227412
DOI: 10.1002/ANIE.202001758