Magnesium in PDB 6wgi: Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution

All present enzymatic activity of Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution:
3.6.4.12;

The binding sites of Magnesium atom in the Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution (pdb code 6wgi). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution, PDB code: 6wgi:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2002 b:0.9 occ:1.00 OD1 A:ASP566 2.0 0.4 1.0 N A:LEU565 2.2 0.1 1.0 C A:LEU565 2.3 0.1 1.0 N A:ASP566 2.5 0.4 1.0 CA A:LEU565 2.7 0.1 1.0 C A:LEU564 2.7 0.3 1.0 O A:LEU565 2.8 0.1 1.0 CA A:ASP566 3.0 0.4 1.0 O A:ILE596 3.1 0.7 1.0 CG A:ASP566 3.1 0.4 1.0 CA A:LEU564 3.4 0.3 1.0 O A:LEU564 3.4 0.3 1.0 CB A:ASP566 3.6 0.4 1.0 CB A:LEU564 3.7 0.3 1.0 CB A:LEU565 3.8 0.1 1.0 N A:VAL598 3.8 0.8 1.0 OD2 A:ASP566 4.2 0.4 1.0 C A:ILE596 4.3 0.7 1.0 CB A:VAL598 4.3 0.8 1.0 C A:ASP566 4.3 0.4 1.0 CA A:ALA597 4.4 0.7 1.0 CG2 A:VAL598 4.4 0.8 1.0 C A:ALA597 4.5 0.7 1.0 CA A:VAL598 4.6 0.8 1.0 CG A:LEU564 4.7 0.3 1.0 N A:LEU564 4.7 0.3 1.0 O A:VAL598 4.8 0.8 1.0 N A:ALA597 4.8 0.7 1.0 O A:ILE513 4.9 0.1 1.0

Magnesium binding site 2 out of 2 in the Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Atomic Model of the Mutant Occm (Orc-CDC6-CDT1-MCM2-7 with MCM6 Whd Truncation) Loaded on Dna at 10.5 A Resolution within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg2002 b:98.5 occ:1.00 O2G E:AGS2001 2.0 0.4 1.0 O2B E:AGS2001 2.0 0.4 1.0 O2A E:AGS2001 2.1 0.4 1.0 O1A E:AGS2001 2.1 0.4 1.0 PA E:AGS2001 2.5 0.4 1.0 CG2 E:THR44 2.5 0.7 1.0 OG1 E:THR44 2.5 0.7 1.0 PG E:AGS2001 2.6 0.4 1.0 S1G E:AGS2001 2.8 0.4 1.0 PB E:AGS2001 2.9 0.4 1.0 CB E:THR44 3.0 0.7 1.0 O3B E:AGS2001 3.1 0.4 1.0 O3A E:AGS2001 3.2 0.4 1.0 N E:THR44 3.6 0.7 1.0 CA E:THR44 3.9 0.7 1.0 O5' E:AGS2001 3.9 0.4 1.0 O3G E:AGS2001 4.1 0.4 1.0 O1B E:AGS2001 4.3 0.4 1.0 CG E:LYS43 4.5 98.2 1.0 N E:LYS43 4.6 98.2 1.0 C E:THR44 4.8 0.7 1.0 C E:LYS43 4.8 98.2 1.0 N E:TYR45 4.9 0.4 1.0

Z.Yuan, S.Schneider, T.Dodd, A.Riera, L.Bai, C.Yan, I.Magdalou, I.Ivanov, B.Stillman, H.Li, C.Speck. Structural Mechanism of Helicase Loading Onto Replication Origin Dna By Orc-CDC6. Proc.Natl.Acad.Sci.Usa V. 117 17747 2020.
ISSN: ESSN 1091-6490
PubMed: 32669428
DOI: 10.1073/PNAS.2006231117