Magnesium in PDB 6z7z: Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab

Protein crystallography data

The structure of Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab, PDB code: 6z7z was solved by E.Johansson, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.99 / 2.40
Space group C 1 2 1
Cell size a, b, c (Å), α, β, γ (°) 109.67, 171.55, 83.17, 90, 135.89, 90
R / Rfree (%) 21 / 25.9

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab (pdb code 6z7z). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab, PDB code: 6z7z:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 6z7z

Go back to Magnesium Binding Sites List in 6z7z
Magnesium binding site 1 out of 2 in the Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
F:Mg101

b:33.8
occ:1.00
O F:HOH206 3.0 41.1 1.0
N F:CYS7 3.3 40.0 1.0
N F:LEU6 3.4 41.0 1.0
N F:VAL12 3.5 36.4 1.0
N F:LEU11 3.6 45.4 1.0
CB F:CYS7 3.7 39.7 1.0
CG2 F:VAL12 3.7 35.1 1.0
CB F:HIS5 3.7 44.6 1.0
O F:HOH202 3.7 50.6 1.0
CB F:VAL12 3.9 38.9 1.0
CA F:CYS7 4.0 32.8 1.0
CA F:HIS5 4.0 48.7 1.0
SG F:CYS7 4.1 35.2 1.0
C F:HIS5 4.1 47.2 1.0
CA F:LEU6 4.2 40.3 1.0
C F:LEU6 4.2 40.9 1.0
C F:HIS10 4.2 42.5 1.0
CB F:LEU11 4.3 40.9 1.0
O F:CYS7 4.3 46.5 1.0
CA F:LEU11 4.3 40.2 1.0
CA F:HIS10 4.3 39.3 1.0
CA F:VAL12 4.4 33.9 1.0
CB F:LEU6 4.4 40.6 1.0
C F:LEU11 4.4 38.6 1.0
C F:CYS7 4.6 42.3 1.0
CG F:HIS5 4.8 50.4 1.0
N F:HIS10 4.9 37.1 1.0
ND1 F:HIS5 4.9 48.2 1.0

Magnesium binding site 2 out of 2 in 6z7z

Go back to Magnesium Binding Sites List in 6z7z
Magnesium binding site 2 out of 2 in the Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Porcine Insulin in Complex with the Analytical Antibody Oxi-005 Fab within 5.0Å range:
probe atom residue distance (Å) B Occ
H:Mg101

b:33.6
occ:1.00
N H:VAL12 3.4 41.2 1.0
N H:CYS7 3.4 37.0 1.0
N H:LEU11 3.4 41.4 1.0
CG2 H:VAL12 3.6 41.8 1.0
N H:LEU6 3.6 45.5 1.0
CB H:CYS7 3.7 42.3 1.0
CB H:HIS5 3.7 46.0 1.0
CB H:VAL12 3.9 39.5 1.0
C H:HIS10 4.1 44.2 1.0
CA H:CYS7 4.1 38.8 1.0
CA H:LEU11 4.1 40.6 1.0
CB H:LEU11 4.1 44.4 1.0
CA H:HIS5 4.2 47.3 1.0
SG H:CYS7 4.2 41.3 1.0
CA H:HIS10 4.2 39.6 1.0
O H:CYS7 4.2 40.9 1.0
C H:LEU11 4.3 35.7 1.0
CA H:VAL12 4.3 39.5 1.0
C H:HIS5 4.3 45.1 1.0
CA H:LEU6 4.3 39.8 1.0
C H:LEU6 4.4 35.9 1.0
CB H:LEU6 4.6 29.9 1.0
C H:CYS7 4.6 42.8 1.0
CG H:HIS5 4.7 54.3 1.0
N H:HIS10 4.8 34.7 1.0
CD2 H:HIS5 4.9 52.6 1.0
O H:HIS10 5.0 43.0 1.0

Reference:

E.Johansson, X.Wu, B.Yu, Z.Yang, Z.Cao, C.Wiberg, C.B.Jeppesen, F.Poulsen. Insulin Binding to the Analytical Antibody Sandwich Pair Oxi-005 and Hui-018: Epitope Mapping and Binding Properties. Protein Sci. 2020.
ISSN: ESSN 1469-896X
PubMed: 33277949
DOI: 10.1002/PRO.4009
Page generated: Mon Jan 25 15:19:51 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy