Magnesium in PDB 7aea: Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2

All present enzymatic activity of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2:
2.7.7.6;

The structure of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 also contains other interesting chemical elements:

Zinc	(Zn)	7 atoms
Iron	(Fe)	4 atoms

The binding sites of Magnesium atom in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 (pdb code 7aea). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2, PDB code: 7aea:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Human Rna Polymerase III Elongation Complex 2 within 5.0Å range: probe atom residue distance (Å) B Occ R:Mg101 b:70.8 occ:1.00 O3' R:G19 1.7 115.7 1.0 OD1 A:ASP499 2.1 69.5 1.0 OD1 A:ASP501 2.5 70.1 1.0 OD2 A:ASP499 2.5 69.5 1.0 CG A:ASP499 2.6 69.5 1.0 OD1 A:ASP503 2.9 79.2 1.0 C3' R:G19 3.1 115.7 1.0 CG A:ASP501 3.3 70.1 1.0 OD2 A:ASP501 3.5 70.1 1.0 C4' R:G19 3.7 115.7 1.0 O2' R:G19 3.9 115.7 1.0 CG A:ASP503 3.9 79.2 1.0 C2' R:G19 4.0 115.7 1.0 CB A:ASP499 4.1 69.5 1.0 CB A:ASP503 4.1 79.2 1.0 C5' R:G19 4.2 115.7 1.0 NH2 A:ARG464 4.2 78.0 1.0 N A:ASP499 4.5 69.5 1.0 N A:ASP501 4.8 70.1 1.0 CA A:ASP499 4.8 69.5 1.0 CB A:ASP501 4.8 70.1 1.0 O5' R:G19 4.8 115.7 1.0 CA A:ASP503 4.9 79.2 1.0

M.Girbig, A.D.Misiaszek, M.K.Vorlaender, A.Lafita, H.Groetsch, F.Baudin, A.Bateman, C.W.Mueller. Cryo-Em Structures of Human Rna Polymerase III in Its Unbound and Transcribing States To Be Published.
DOI: 10.1038/S41594-020-00555-5