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Magnesium in PDB 7aom: Structure of NUDT15 in Complex with Ganciclovir TriphosphateEnzymatic activity of Structure of NUDT15 in Complex with Ganciclovir Triphosphate
All present enzymatic activity of Structure of NUDT15 in Complex with Ganciclovir Triphosphate:
3.6.1.9; Protein crystallography data
The structure of Structure of NUDT15 in Complex with Ganciclovir Triphosphate, PDB code: 7aom
was solved by
D.Rehling,
S.M.Zhang,
T.Helleday,
P.Stenmark,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of NUDT15 in Complex with Ganciclovir Triphosphate
(pdb code 7aom). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of NUDT15 in Complex with Ganciclovir Triphosphate, PDB code: 7aom: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 7aomGo back to Magnesium Binding Sites List in 7aom
Magnesium binding site 1 out
of 2 in the Structure of NUDT15 in Complex with Ganciclovir Triphosphate
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 7aomGo back to Magnesium Binding Sites List in 7aom
Magnesium binding site 2 out
of 2 in the Structure of NUDT15 in Complex with Ganciclovir Triphosphate
Mono view Stereo pair view
Reference:
S.M.Zhang,
D.Rehling,
A.-S.Jemth,
A.Throup,
N.Landazuri,
I.Almlof,
M.Goettmann,
N.C.K.Valerie,
S.R.Borhade,
P.Wakchaure,
B.D.G.Page,
M.Desroses,
E.J.Homan,
M.Scobie,
S.G.Rudd,
U.Warpman Berglund,
C.Soderberg-Naucler,
P.Stenmark,
T.Helleday.
NUDT15-Mediated Hydrolysis Limits the Efficacy of Anti-Hcmv Drug Ganciclovir Cell Chem Biol 2021.
Page generated: Sun Jul 11 15:42:16 2021
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