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Magnesium in PDB 7bbj: CD73 in Complex with the Humanized Antagonistic Antibody MAB19Enzymatic activity of CD73 in Complex with the Humanized Antagonistic Antibody MAB19
All present enzymatic activity of CD73 in Complex with the Humanized Antagonistic Antibody MAB19:
3.1.3.5; Protein crystallography data
The structure of CD73 in Complex with the Humanized Antagonistic Antibody MAB19, PDB code: 7bbj
was solved by
J.Boettcher,
F.Han,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7bbj:
The structure of CD73 in Complex with the Humanized Antagonistic Antibody MAB19 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the CD73 in Complex with the Humanized Antagonistic Antibody MAB19
(pdb code 7bbj). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the CD73 in Complex with the Humanized Antagonistic Antibody MAB19, PDB code: 7bbj: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 7bbjGo back to Magnesium Binding Sites List in 7bbj
Magnesium binding site 1 out
of 2 in the CD73 in Complex with the Humanized Antagonistic Antibody MAB19
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 7bbjGo back to Magnesium Binding Sites List in 7bbj
Magnesium binding site 2 out
of 2 in the CD73 in Complex with the Humanized Antagonistic Antibody MAB19
Mono view Stereo pair view
Reference:
M.Wurm,
O.Schaaf,
K.Reutner,
R.Ganesan,
S.Mostbock,
C.Pelster,
J.Bottcher,
C.Taubert,
I.Alt,
G.Serna,
A.Auguste,
K.B.Stadermann,
D.Delic,
F.Han,
J.Capdevila,
P.G.Nuciforo,
R.Kroe-Barrett,
P.J.Adam,
A.B.Vogt,
I.Hofmann.
A Novel Antagonistic CD73 Antibody For Inhibition of the Immunosuppressive Adenosine Pathway Mol.Cancer Ther. 2021.
Page generated: Thu Mar 31 04:05:19 2022
ISSN: ESSN 1538-8514 DOI: 10.1158/1535-7163.MCT-21-0107 |
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