Magnesium in PDB 7bdp: 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017

Enzymatic activity of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017

All present enzymatic activity of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017:
5.2.1.8;

Protein crystallography data

The structure of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017, PDB code: 7bdp was solved by M.Wolter, L.V.Dijck, P.J.Cossar, C.Ottmann, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 41.63 / 1.75
Space group C 2 2 21
Cell size a, b, c (Å), α, β, γ (°) 81.989, 111.691, 62.463, 90, 90, 90
R / Rfree (%) 17.3 / 21.7

Other elements in 7bdp:

The structure of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017 also contains other interesting chemical elements:

Chlorine (Cl) 1 atom

Magnesium Binding Sites:

The binding sites of Magnesium atom in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017 (pdb code 7bdp). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017, PDB code: 7bdp:

Magnesium binding site 1 out of 1 in 7bdp

Go back to Magnesium Binding Sites List in 7bdp
Magnesium binding site 1 out of 1 in the 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of 14-3-3 Sigma with PIN1 Binding Site PS72 and Covalently Bound LVD1017 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg302

b:14.1
occ:1.00
OE1 A:GLU35 2.2 19.3 1.0
O A:HOH458 2.2 28.6 1.0
O A:GLU110 2.3 14.0 1.0
O A:HOH548 2.4 23.9 1.0
CD A:GLU35 2.8 25.7 1.0
OE2 A:GLU35 2.9 27.8 1.0
C A:GLU110 3.5 14.4 1.0
N A:GLY112 3.9 18.1 1.0
CG A:GLU35 4.3 16.0 1.0
OE1 A:GLU110 4.3 33.3 1.0
CA A:GLU110 4.4 9.5 1.0
O A:HOH622 4.4 29.2 1.0
N A:ALA111 4.4 10.3 1.0
CA A:GLY112 4.5 23.0 1.0
CA A:ALA111 4.5 10.5 1.0
CB A:GLU110 4.6 12.9 1.0
O A:HOH583 4.6 31.9 1.0
C A:ALA111 4.6 15.2 1.0

Reference:

P.J.Cossar, M.Wolter, L.Van Dijck, D.Valenti, L.M.Levy, C.Ottmann, L.Brunsveld. Reversible Covalent Imine-Tethering For Selective Stabilization of 14-3-3 Hub Protein Interactions. J.Am.Chem.Soc. 2021.
ISSN: ESSN 1520-5126
PubMed: 34047554
DOI: 10.1021/JACS.1C03035
Page generated: Sun Jul 11 15:47:43 2021

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy