Magnesium in PDB 7bkp: Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp

All present enzymatic activity of Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp:
3.6.4.13;

The structure of Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp also contains other interesting chemical elements:

Zinc

(Zn)

1 atom

The binding sites of Magnesium atom in the Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp (pdb code 7bkp). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp, PDB code: 7bkp:

Magnesium binding site 1 out of 1 in the Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryoem Structure of Disease Related M854K MDA5-Dsrna Filament in Complex with Atp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1103 b:50.1 occ:1.00 O3G A:ATP1102 1.8 49.0 1.0 O2B A:ATP1102 2.4 49.0 1.0 OG1 A:THR337 3.2 38.9 1.0 PG A:ATP1102 3.2 49.0 1.0 PB A:ATP1102 3.5 49.0 1.0 O1G A:ATP1102 3.7 49.0 1.0 HE2 A:LYS336 3.8 38.9 1.0 O3B A:ATP1102 3.9 49.0 1.0 HB2 A:LYS336 4.0 38.9 1.0 O1B A:ATP1102 4.2 49.0 1.0 OD2 A:ASP444 4.2 24.9 1.0 H A:THR337 4.3 38.9 1.0 O2G A:ATP1102 4.3 49.0 1.0 CB A:THR337 4.6 38.9 1.0 HD21 A:LEU373 4.6 33.9 1.0 CE A:LYS336 4.7 38.9 1.0 O2A A:ATP1102 4.8 49.0 1.0 OD1 A:ASP444 4.8 24.9 1.0 N A:THR337 4.8 38.9 1.0 O3A A:ATP1102 4.8 49.0 1.0 HZ3 A:LYS336 4.8 38.9 1.0 O1A A:ATP1102 4.9 49.0 1.0 HB A:THR337 4.9 38.9 1.0 HD11 A:LEU369 4.9 29.4 1.0 CB A:LYS336 5.0 38.9 1.0 CG A:ASP444 5.0 24.9 1.0

Q.Yu, A.Herrero Del Valle, R.Singh, Y.Modis. MDA5 Autoimmune Disease Variant M854K Prevents Atp-Dependent Structural Discrimination of Viral and Cellular Rna. Nat Commun 2021.
ISSN: ESSN 2041-1723
DOI: 10.1038/S41467-021-27062-5