Magnesium in PDB 7bsq: Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State

The structure of Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Aluminium	(Al)	1 atom

The binding sites of Magnesium atom in the Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State (pdb code 7bsq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State, PDB code: 7bsq:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1103 b:42.6 occ:1.00 CA A:GLY815 1.9 27.6 1.0 N A:GLY815 1.9 27.6 1.0 O A:ILE814 2.0 27.6 1.0 C A:ILE814 2.0 27.6 1.0 C A:GLY815 2.6 27.6 1.0 CG2 A:THR413 2.7 36.0 1.0 N A:ASP816 3.3 35.5 1.0 O A:GLY815 3.3 27.6 1.0 CG1 A:ILE814 3.3 27.6 1.0 CA A:ILE814 3.3 27.6 1.0 CB A:THR413 3.6 36.0 1.0 CB A:ILE814 3.7 27.6 1.0 CG2 A:ILE814 3.9 27.6 1.0 CD1 A:ILE833 4.0 27.6 1.0 OG1 A:THR413 4.1 36.0 1.0 CG1 A:ILE833 4.3 27.6 1.0 CB A:ASP409 4.3 35.3 1.0 N A:ASP409 4.4 35.3 1.0 N A:ILE814 4.4 27.6 1.0 CA A:ASP816 4.5 35.5 1.0 O A:ILE831 4.5 27.6 1.0 CD1 A:ILE814 4.6 27.6 1.0 CB A:ASP816 4.7 35.5 1.0 OD2 A:ASP820 4.9 38.1 1.0 CA A:ASP409 4.9 35.3 1.0 CB A:ILE833 4.9 27.6 1.0 CA A:THR413 4.9 36.0 1.0

Magnesium binding site 2 out of 2 in the Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Cryo-Em Structure of A Human ATP11C-CDC50A Flippase in E1ALF-Adp State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1104 b:50.6 occ:1.00 O2A A:ADP1102 1.8 63.5 1.0 O3B A:ADP1102 2.6 63.5 1.0 PA A:ADP1102 3.1 63.5 1.0 O5' A:ADP1102 3.4 63.5 1.0 H8 A:ADP1102 3.4 63.5 1.0 OE2 A:GLU837 3.6 55.9 1.0 O3A A:ADP1102 3.7 63.5 1.0 PB A:ADP1102 3.8 63.5 1.0 C8 A:ADP1102 4.1 63.5 1.0 N7 A:ADP1102 4.3 63.5 1.0 O1A A:ADP1102 4.4 63.5 1.0 NH2 A:ARG594 4.5 63.3 1.0 CD A:GLU837 4.5 55.9 1.0 OD1 A:ASP497 4.5 71.6 1.0 H3' A:ADP1102 4.6 63.5 1.0 O2B A:ADP1102 4.7 63.5 1.0 NH1 A:ARG594 4.8 63.3 1.0 O1B A:ADP1102 4.8 63.5 1.0 C5' A:ADP1102 4.8 63.5 1.0 OE1 A:GLU837 4.9 55.9 1.0

H.Nakanishi, T.Nishizawa, K.Segawa, O.Nureki, Y.Fujiyoshi, S.Nagata, K.Abe. Transport Cycle of Plasma Membrane Flippase ATP11C By Cryo-Em. Cell Rep V. 32 08208 2020.
ISSN: ESSN 2211-1247
PubMed: 32997992
DOI: 10.1016/J.CELREP.2020.108208