Magnesium in PDB 7d9u: Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State

All present enzymatic activity of Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State:
4.6.1.2;

The binding sites of Magnesium atom in the Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State (pdb code 7d9u). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State, PDB code: 7d9u:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1002 b:30.0 occ:1.00 O2B A:G2P1001 2.3 127.3 1.0 CG A:ASP486 2.3 117.6 1.0 OD2 A:ASP486 2.4 117.6 1.0 O A:ILE487 2.4 118.3 1.0 O1G A:G2P1001 2.5 127.3 1.0 OD1 A:ASP486 2.5 117.6 1.0 MG A:MG1003 2.8 30.0 1.0 CB A:ASP486 3.1 117.6 1.0 C A:ILE487 3.1 118.3 1.0 C A:ASP486 3.1 117.6 1.0 O A:ASP486 3.3 117.6 1.0 N A:ILE487 3.4 118.3 1.0 PB A:G2P1001 3.5 127.3 1.0 NH2 A:ARG574 3.6 122.2 1.0 CA A:ASP486 3.6 117.6 1.0 O3B A:G2P1001 3.7 127.3 1.0 PG A:G2P1001 3.7 127.3 1.0 N A:VAL488 3.9 125.0 1.0 CA A:ILE487 3.9 118.3 1.0 CA A:VAL488 4.0 125.0 1.0 O3G A:G2P1001 4.5 127.3 1.0 C3A A:G2P1001 4.5 127.3 1.0 CZ A:ARG574 4.6 122.2 1.0 O1B A:G2P1001 4.6 127.3 1.0 O1A A:G2P1001 4.6 127.3 1.0 OD2 A:ASP530 4.7 116.4 1.0 NE A:ARG574 4.7 122.2 1.0 C A:VAL488 4.7 125.0 1.0 N A:GLY489 4.8 125.2 1.0 O2G A:G2P1001 4.8 127.3 1.0 CG1 A:ILE487 4.9 118.3 1.0 N A:ASP486 4.9 117.6 1.0

Magnesium binding site 2 out of 2 in the Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1003 b:30.0 occ:1.00 OD2 A:ASP486 2.2 117.6 1.0 OD1 A:ASP486 2.3 117.6 1.0 O5' A:G2P1001 2.4 127.3 1.0 O2B A:G2P1001 2.5 127.3 1.0 CG A:ASP486 2.6 117.6 1.0 C3A A:G2P1001 2.7 127.3 1.0 PA A:G2P1001 2.7 127.3 1.0 MG A:MG1002 2.8 30.0 1.0 O1A A:G2P1001 2.9 127.3 1.0 PB A:G2P1001 2.9 127.3 1.0 OD2 A:ASP530 3.0 116.4 1.0 O3B A:G2P1001 3.2 127.3 1.0 CG A:ASP530 3.3 116.4 1.0 OD1 A:ASP530 3.3 116.4 1.0 C5' A:G2P1001 3.7 127.3 1.0 O1G A:G2P1001 4.0 127.3 1.0 CB A:ASP486 4.1 117.6 1.0 O2A A:G2P1001 4.2 127.3 1.0 O A:ILE487 4.2 118.3 1.0 PG A:G2P1001 4.3 127.3 1.0 CB A:ASP530 4.4 116.4 1.0 O1B A:G2P1001 4.4 127.3 1.0 CB A:PHE490 4.7 124.6 1.0 C4' A:G2P1001 4.8 127.3 1.0 CA A:ASP486 4.9 117.6 1.0

L.Chen, R.Liu, Y.Kang. Structure of Human Soluble Guanylate Cyclase in the Cinciguat-Bound Activated State To Be Published.