Magnesium in PDB 7e0z: Crystal Structure of Pkac-Pln Complex

All present enzymatic activity of Crystal Structure of Pkac-Pln Complex:
2.7.11.11;

The structure of Crystal Structure of Pkac-Pln Complex, PDB code: 7e0z was solved by J.Qin, Z.Yuchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.43 / 2.16
Space group	P 2 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.571, 70.485, 99.035, 90, 90, 90
R / Rfree (%)	17.9 / 22.8

The binding sites of Magnesium atom in the Crystal Structure of Pkac-Pln Complex (pdb code 7e0z). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Pkac-Pln Complex, PDB code: 7e0z:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Pkac-Pln Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Pkac-Pln Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:26.0 occ:1.00 O A:HOH602 2.0 26.5 1.0 O1B A:ANP401 2.1 25.2 1.0 O2G A:ANP401 2.1 27.9 1.0 OD1 A:ASP184 2.3 27.3 1.0 OD2 A:ASP184 2.4 25.9 1.0 CG A:ASP184 2.7 26.5 1.0 PG A:ANP401 3.4 27.5 1.0 PB A:ANP401 3.4 27.0 1.0 N3B A:ANP401 3.8 22.8 1.0 O1G A:ANP401 3.9 28.3 1.0 OD2 A:ASP166 4.0 27.4 1.0 OG B:SER16 4.1 33.7 1.0 MG A:MG403 4.1 24.8 1.0 O A:HOH573 4.1 26.3 1.0 NZ A:LYS72 4.1 20.1 1.0 CB A:ASP184 4.2 22.7 1.0 O2B A:ANP401 4.3 28.5 1.0 O3A A:ANP401 4.4 25.6 1.0 CA A:GLY186 4.5 27.0 1.0 O2A A:ANP401 4.5 21.1 1.0 CB B:SER16 4.5 30.6 1.0 N A:GLY186 4.5 25.3 1.0 O3G A:ANP401 4.6 25.4 1.0 PA A:ANP401 4.8 22.9 1.0 O1A A:ANP401 4.9 26.5 1.0 CA A:ASP184 4.9 25.1 1.0 CE2 A:PHE187 5.0 26.1 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Pkac-Pln Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Pkac-Pln Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:24.8 occ:1.00 OD1 A:ASN171 2.0 21.4 1.0 O2A A:ANP401 2.0 21.1 1.0 OD2 A:ASP184 2.1 25.9 1.0 O1G A:ANP401 2.1 28.3 1.0 O A:HOH559 2.2 23.2 1.0 N3B A:ANP401 2.9 22.8 1.0 PG A:ANP401 2.9 27.5 1.0 CG A:ASN171 3.0 25.4 1.0 CG A:ASP184 3.1 26.5 1.0 ND2 A:ASN171 3.4 25.1 1.0 PA A:ANP401 3.5 22.9 1.0 CB A:ASP184 3.6 22.7 1.0 O2G A:ANP401 3.7 27.9 1.0 PB A:ANP401 3.8 27.0 1.0 O1B A:ANP401 3.9 25.2 1.0 CE A:LYS168 3.9 21.8 1.0 O3A A:ANP401 4.1 25.6 1.0 MG A:MG402 4.1 26.0 1.0 O A:HOH521 4.1 29.3 1.0 O B:HOH111 4.2 22.8 1.0 NZ A:LYS168 4.2 23.9 1.0 OD1 A:ASP184 4.2 27.3 1.0 O3G A:ANP401 4.3 25.4 1.0 O1A A:ANP401 4.3 26.5 1.0 O3' A:ANP401 4.3 24.8 1.0 OD2 A:ASP166 4.3 27.4 1.0 CB A:ASN171 4.4 25.8 1.0 O5' A:ANP401 4.5 26.3 1.0 CA A:ASN171 4.7 23.3 1.0 C5' A:ANP401 4.7 22.8 1.0 O A:HOH552 4.8 29.5 1.0 C3' A:ANP401 4.9 21.5 1.0 O A:GLU170 4.9 21.4 1.0 N A:ASN171 4.9 22.4 1.0

J.Qin, J.Zhang, L.Lin, O.Haji-Ghassemi, Z.Lin, K.J.Woycechowsky, F.Van Petegem, Y.Zhang, Z.Yuchi. Structures of Pka-Phospholamban Complexes Reveal A Mechanism of Familial Dilated Cardiomyopathy. Elife V. 11 2022.
ISSN: ESSN 2050-084X
PubMed: 35297759
DOI: 10.7554/ELIFE.75346