Magnesium in PDB 7e11: Crystal Structure of Pkac-Pln R9C Complex

All present enzymatic activity of Crystal Structure of Pkac-Pln R9C Complex:
2.7.11.11;

The structure of Crystal Structure of Pkac-Pln R9C Complex, PDB code: 7e11 was solved by J.Qin, L.Lin, Z.Yuchi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.19 / 3.43
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	50.91, 104.883, 168.096, 90, 90, 90
R / Rfree (%)	25.7 / 31.7

The binding sites of Magnesium atom in the Crystal Structure of Pkac-Pln R9C Complex (pdb code 7e11). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Pkac-Pln R9C Complex, PDB code: 7e11:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Pkac-Pln R9C Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Pkac-Pln R9C Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg402 b:86.4 occ:1.00 O2G A:ANP401 2.1 86.3 1.0 OD1 A:ASP184 2.1 86.5 1.0 O1B A:ANP401 2.4 85.6 1.0 CG A:ASP184 2.8 86.3 1.0 OD2 A:ASP184 2.9 85.7 1.0 PG A:ANP401 3.5 85.6 1.0 PB A:ANP401 3.8 86.0 1.0 OD2 A:ASP166 3.9 88.5 1.0 O1G A:ANP401 4.1 86.4 1.0 N3B A:ANP401 4.1 86.2 1.0 CA A:GLY186 4.2 88.2 1.0 N A:GLY186 4.2 88.8 1.0 CB A:ASP184 4.3 86.5 1.0 OG B:SER16 4.4 88.5 1.0 O2B A:ANP401 4.6 86.9 1.0 O3G A:ANP401 4.6 88.0 1.0 O2A A:ANP401 4.7 85.9 1.0 O A:ASP184 4.7 86.5 1.0 O3A A:ANP401 4.8 85.0 1.0 C A:ASP184 4.8 87.4 1.0 CZ A:PHE187 4.9 89.7 1.0 CA A:ASP184 4.9 87.1 1.0 CB B:SER16 4.9 88.5 1.0 CE2 A:PHE187 4.9 90.0 1.0 C A:GLY186 4.9 89.3 1.0 CG A:ASP166 4.9 87.9 1.0 CE1 A:PHE187 5.0 87.9 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Pkac-Pln R9C Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Pkac-Pln R9C Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg403 b:86.7 occ:1.00 O1G A:ANP401 2.3 86.4 1.0 OD1 A:ASN171 2.4 84.7 1.0 O2A A:ANP401 2.5 85.9 1.0 N3B A:ANP401 2.8 86.2 1.0 OD2 A:ASP184 2.9 85.7 1.0 PG A:ANP401 3.1 85.6 1.0 CG A:ASN171 3.5 84.9 1.0 CE A:LYS168 3.6 86.0 1.0 O A:GLU170 3.8 87.7 1.0 NZ A:LYS168 3.9 86.3 1.0 ND2 A:ASN171 3.9 85.9 1.0 CB A:GLU170 4.0 88.0 1.0 PA A:ANP401 4.0 81.3 1.0 O3' A:ANP401 4.1 88.8 1.0 CG A:ASP184 4.1 86.3 1.0 O2G A:ANP401 4.1 86.3 1.0 C A:GLU170 4.2 87.5 1.0 PB A:ANP401 4.2 86.0 1.0 O3G A:ANP401 4.3 88.0 1.0 NH2 B:ARG13 4.6 89.1 1.0 O3A A:ANP401 4.6 85.0 1.0 C5' A:ANP401 4.6 86.6 1.0 CB A:ASP184 4.6 86.5 1.0 O1B A:ANP401 4.7 85.6 1.0 C3' A:ANP401 4.7 87.5 1.0 O5' A:ANP401 4.7 85.2 1.0 N A:ASN171 4.7 87.6 1.0 CB A:ASN171 4.7 85.1 1.0 CA A:GLU170 4.8 87.1 1.0 CA A:ASN171 4.9 86.2 1.0 O B:ARG14 4.9 89.8 1.0 O1A A:ANP401 5.0 83.2 1.0

J.Qin, J.Zhang, L.Lin, O.Haji-Ghassemi, Z.Lin, K.J.Woycechowsky, F.Van Petegem, Y.Zhang, Z.Yuchi. Structures of Pka-Phospholamban Complexes Reveal A Mechanism of Familial Dilated Cardiomyopathy. Elife V. 11 2022.
ISSN: ESSN 2050-084X
PubMed: 35297759
DOI: 10.7554/ELIFE.75346