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Atomistry » Magnesium » PDB 7e21-7eg1 » 7ebb » |
Magnesium in PDB 7ebb: Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2Enzymatic activity of Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2
All present enzymatic activity of Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2:
2.7.11.2; Protein crystallography data
The structure of Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2, PDB code: 7ebb
was solved by
T.Orita,
S.Doi,
T.Iwanaga,
T.Adachi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2
(pdb code 7ebb). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2, PDB code: 7ebb: Magnesium binding site 1 out of 1 in 7ebbGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Crystal Structure of Human Pyruvate Dehydrogenase Kinase 4 in Complex with Compound 2
![]() Mono view ![]() Stereo pair view
Reference:
T.Akaki,
Y.Bessho,
T.Ito,
S.Fujioka,
M.Ubukata,
G.Mori,
K.Yamanaka,
T.Orita,
S.Doi,
T.Iwanaga,
K.Ikegashira,
Y.Hantani,
I.Nakanishi,
T.Adachi.
Fragment-Based Lead Discovery to Identify Novel Inhibitors That Target the Atp Binding Site of Pyruvate Dehydrogenase Kinases. Bioorg.Med.Chem. V. 44 16283 2021.
Page generated: Wed Oct 2 20:34:06 2024
ISSN: ESSN 1464-3391 PubMed: 34274549 DOI: 10.1016/J.BMC.2021.116283 |
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