Magnesium in PDB 7f0d: Cryo-Em Structure of Mycobacterium Tuberculosis 50S Ribosome Subunit Bound with Clarithromycin

The binding sites of Magnesium atom in the Cryo-Em Structure of Mycobacterium Tuberculosis 50S Ribosome Subunit Bound with Clarithromycin (pdb code 7f0d). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of Mycobacterium Tuberculosis 50S Ribosome Subunit Bound with Clarithromycin, PDB code: 7f0d:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of Mycobacterium Tuberculosis 50S Ribosome Subunit Bound with Clarithromycin


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of Mycobacterium Tuberculosis 50S Ribosome Subunit Bound with Clarithromycin within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg3202 b:5.0 occ:1.00 OP1 A:A2300 2.9 3.7 0.3 OP1 A:A2300 3.1 3.7 0.7 NZ E:LYS75 3.2 4.4 1.0 N7 A:G2682 3.6 5.0 1.0 OP2 A:G2682 3.8 5.0 1.0 P A:A2300 3.9 3.7 0.3 OP2 A:G2299 4.0 4.0 1.0 OP2 A:A2300 4.0 3.7 0.7 OP2 A:A2300 4.0 3.7 0.3 P A:A2300 4.0 3.7 0.7 C5 A:C2681 4.1 2.5 1.0 C8 A:G2682 4.3 5.0 1.0 C6 A:C2681 4.4 2.5 1.0 OP2 A:C2681 4.5 2.5 1.0 C4 A:C2681 4.6 2.5 1.0 CE E:LYS75 4.6 4.4 1.0 N7 A:G2683 4.6 2.6 1.0 C5 A:G2682 4.7 5.0 1.0 O5' A:C2681 4.9 2.5 1.0 N4 A:C2681 4.9 2.5 1.0 O6 A:G2682 4.9 5.0 1.0 O5' A:A2300 4.9 3.7 0.3

W.Zhang, Z.Li, Y.Sun, P.Cui, J.Liang, Q.Xing, J.Wu, Y.Xu, W.Zhang, Y.Zhang, L.He, N.Gao. Cryo-Em Structure of Mycobacterium Tuberculosis 50S Ribosomal Subunit Bound with Clarithromycin Reveals Dynamic and Specific Interactions with Macrolides. Emerg Microbes Infect V. 11 293 2022.
ISSN: ESSN 2222-1751
PubMed: 34935599
DOI: 10.1080/22221751.2021.2022439