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Magnesium in PDB 7jv1: Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1Enzymatic activity of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1
All present enzymatic activity of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1:
2.7.11.1; 2.7.12.2; Protein crystallography data
The structure of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1, PDB code: 7jv1
was solved by
Z.M.Khan,
A.C.Dar,
A.P.Scopton,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7jv1:
The structure of Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1
(pdb code 7jv1). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1, PDB code: 7jv1: Magnesium binding site 1 out of 1 in 7jv1Go back to Magnesium Binding Sites List in 7jv1
Magnesium binding site 1 out
of 1 in the Crystal Structure of KSR1:MEK1 in Complex with Amp-Pnp, and Allosteric Mek Inhibitor Aps-9-95-1
Mono view Stereo pair view
Reference:
Z.M.Khan,
A.M.Real,
W.M.Marsiglia,
A.Chow,
M.E.Duffy,
J.R.Yerabolu,
A.P.Scopton,
A.C.Dar.
Structural Basis For the Action of the Drug Trametinib at Ksr-Bound Mek. Nature 2020.
Page generated: Tue Dec 15 03:41:28 2020
ISSN: ESSN 1476-4687 PubMed: 32927473 DOI: 10.1038/S41586-020-2760-4 |
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