Magnesium in PDB 7k5i: Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome

All present enzymatic activity of Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome:
4.2.99.18;

The structure of Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome also contains other interesting chemical elements:

Zinc

(Zn)

3 atoms

The binding sites of Magnesium atom in the Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome (pdb code 7k5i). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome, PDB code: 7k5i:

Magnesium binding site 1 out of 1 in the Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Sars-Cov-2 NSP1 in Complex with Human 40S Ribosome within 5.0Å range: probe atom residue distance (Å) B Occ 2:Mg1901 b:30.0 occ:1.00 OP2 2:A604 2.6 45.3 1.0 OP1 2:G601 3.5 44.7 1.0 O3' 2:A604 3.5 45.3 1.0 P 2:A604 3.9 45.3 1.0 O3' 2:C603 4.1 43.1 1.0 OP2 2:A605 4.1 47.7 1.0 N7 2:A605 4.2 47.7 1.0 CD 1:ARG171 4.2 30.0 1.0 C8 2:A605 4.3 47.7 1.0 P 2:A605 4.4 47.7 1.0 C3' 2:A604 4.4 45.3 1.0 OP2 2:G602 4.4 42.8 1.0 O5' 2:A605 4.6 47.7 1.0 O5' 2:A604 4.6 45.3 1.0 P 2:G601 4.7 44.7 1.0 O2' 2:C603 4.8 43.1 1.0 CG 1:ARG171 4.9 30.0 1.0 OP1 2:A604 5.0 45.3 1.0

M.Shi, L.Wang, P.Fontana, S.Vora, Y.Zhang, T.M.Fu, J.Lieberman, H.Wu. Sars-Cov-2 NSP1 Suppresses Host But Not Viral Translation Through A Bipartite Mechanism. Biorxiv 2020.
PubMed: 32995777
DOI: 10.1101/2020.09.18.302901