Magnesium in PDB 7k7t: Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp

The structure of Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp, PDB code: 7k7t was solved by B.J.Klein, A.H.Tencer, T.G.Kutateladze, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	47.11 / 2.94
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	52.424, 109.934, 70.390, 90.00, 95.95, 90.00
R / Rfree (%)	23.7 / 26.4

The structure of Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Magnesium atom in the Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp (pdb code 7k7t). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp, PDB code: 7k7t:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg502 b:30.3 occ:1.00 O A:HOH601 2.1 33.5 1.0 O1G A:ANP503 2.2 36.8 1.0 O1B A:ANP503 2.2 33.3 1.0 OD1 A:ASN60 2.3 28.5 1.0 O1A A:ANP503 2.3 27.8 1.0 O3A A:ANP503 2.5 30.1 1.0 PB A:ANP503 2.8 31.0 1.0 ND2 A:ASN60 2.8 28.9 1.0 PA A:ANP503 2.8 27.9 1.0 CG A:ASN60 2.9 30.1 1.0 PG A:ANP503 3.2 27.5 1.0 N3B A:ANP503 3.4 29.7 1.0 O5' A:ANP503 3.5 32.8 1.0 O2G A:ANP503 3.6 27.5 1.0 CA A:GLY124 3.9 25.3 1.0 N A:PHE125 4.1 26.3 1.0 N A:GLY124 4.1 25.1 1.0 O2B A:ANP503 4.2 44.2 1.0 O2A A:ANP503 4.2 31.5 1.0 C A:GLY124 4.3 24.0 1.0 CB A:ASN60 4.4 34.6 1.0 OE1 A:GLU56 4.6 27.4 1.0 O3G A:ANP503 4.6 33.9 1.0 CA A:GLY119 4.8 34.0 1.0 C5' A:ANP503 4.8 32.1 1.0 O A:GLU56 5.0 29.7 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human MORC4 Atpase-Cw in Complex with Amppnp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg502 b:26.1 occ:1.00 O B:HOH603 2.2 32.0 1.0 O1A B:ANP503 2.2 26.0 1.0 O1B B:ANP503 2.2 30.0 1.0 OD1 B:ASN60 2.3 26.6 1.0 O1G B:ANP503 2.3 29.7 1.0 O3A B:ANP503 2.7 30.8 1.0 ND2 B:ASN60 2.8 26.4 1.0 CG B:ASN60 2.8 25.9 1.0 PA B:ANP503 2.9 22.4 1.0 PB B:ANP503 2.9 29.1 1.0 O5' B:ANP503 3.5 27.8 1.0 PG B:ANP503 3.5 28.8 1.0 N3B B:ANP503 3.7 30.6 1.0 CA B:GLY124 3.9 26.6 1.0 N B:PHE125 3.9 25.8 1.0 O2G B:ANP503 4.1 27.9 1.0 OE2 B:GLU56 4.2 39.5 1.0 N B:GLY124 4.2 27.3 1.0 C B:GLY124 4.2 23.7 1.0 CB B:ASN60 4.3 26.7 1.0 O2A B:ANP503 4.3 28.8 1.0 O2B B:ANP503 4.3 35.7 1.0 CG B:GLU56 4.6 28.5 1.0 CA B:ASN60 4.8 26.8 1.0 C5' B:ANP503 4.8 27.6 1.0 O3G B:ANP503 4.8 32.3 1.0 O B:GLU56 4.8 25.8 1.0 CD B:GLU56 4.9 30.4 1.0 CA B:PHE125 4.9 24.4 1.0 CB B:PHE125 5.0 25.1 1.0

A.H.Tencer, K.L.Cox, G.M.Wright, Y.Zhang, C.J.Petell, B.J.Klein, B.D.Strahl, J.C.Black, M.G.Poirier, T.G.Kutateladze. Molecular Mechanism of the MORC4 Atpase Activation. Nat Commun V. 11 5466 2020.
ISSN: ESSN 2041-1723
PubMed: 33122719
DOI: 10.1038/S41467-020-19278-8