Magnesium in PDB 7krn: Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc

All present enzymatic activity of Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc:
2.7.7.48; 3.6.4.12; 3.6.4.13;

The structure of Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc also contains other interesting chemical elements:

Zinc	(Zn)	5 atoms
Aluminium	(Al)	1 atom
Fluorine	(F)	3 atoms

The binding sites of Magnesium atom in the Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc (pdb code 7krn). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc, PDB code: 7krn:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1003 b:39.3 occ:1.00 O2A A:ADP1004 1.8 41.9 1.0 O1A A:ADP1004 1.9 41.9 1.0 PA A:ADP1004 2.0 41.9 1.0 OD2 A:ASP218 2.0 29.5 1.0 O1B A:ADP1004 2.1 41.9 1.0 OD1 A:ASN209 2.1 23.4 1.0 O3A A:ADP1004 3.1 41.9 1.0 CG A:ASP218 3.1 29.5 1.0 CG A:ASN209 3.2 23.4 1.0 PB A:ADP1004 3.2 41.9 1.0 O5' A:ADP1004 3.4 41.9 1.0 CB A:ASP218 3.6 29.5 1.0 ND2 A:ASN209 3.7 23.4 1.0 OD2 A:ASP208 3.7 20.0 1.0 C5' A:ADP1004 3.9 41.9 1.0 O2B A:ADP1004 4.0 41.9 1.0 OD1 A:ASP218 4.1 29.5 1.0 O A:ASP208 4.3 20.0 1.0 CB A:ASN209 4.4 23.4 1.0 O3B A:ADP1004 4.4 41.9 1.0 C4' A:ADP1004 4.7 41.9 1.0 CG A:ASP208 4.7 20.0 1.0 CA A:ASN209 4.7 23.4 1.0 C A:ASP208 4.9 20.0 1.0

Magnesium binding site 2 out of 2 in the Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of Sars-Cov-2 Backtracked Complex Bound to NSP13 Helicase - NSP13(1)-Btc within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg705 b:66.3 occ:1.00 O2B E:ADP704 1.5 69.2 1.0 PB E:ADP704 1.7 69.2 1.0 F3 E:AF3706 1.9 62.4 1.0 OG E:SER289 2.1 53.2 1.0 O1B E:ADP704 2.2 69.2 1.0 O3B E:ADP704 2.2 69.2 1.0 AL E:AF3706 2.3 62.4 1.0 F1 E:AF3706 3.1 62.4 1.0 O3A E:ADP704 3.3 69.2 1.0 CB E:SER289 3.3 53.2 1.0 F2 E:AF3706 3.4 62.4 1.0 NZ E:LYS288 3.7 51.4 1.0 OE2 E:GLU375 4.0 45.2 1.0 N E:SER289 4.0 53.2 1.0 PA E:ADP704 4.2 69.2 1.0 O2A E:ADP704 4.2 69.2 1.0 CA E:SER289 4.3 53.2 1.0 CA E:GLY538 4.3 73.2 1.0 CE E:LYS288 4.4 51.4 1.0 OD2 E:ASP374 4.5 39.9 1.0 O1A E:ADP704 4.5 69.2 1.0 O E:GLY538 4.6 73.2 1.0 N E:GLY538 4.7 73.2 1.0 OD1 E:ASP374 4.8 39.9 1.0 C E:GLY538 4.9 73.2 1.0 NH1 E:ARG567 4.9 65.7 1.0 CB E:LYS288 5.0 51.4 1.0

B.Malone, J.Chen, Q.Wang, E.C.Llewellyn, Y.J.Choi, P.D.B.Olinares, X.Cao, C.Hernandez, E.Eng, B.T.Chait, D.E.Shaw, R.Landick, S.A.Darst, E.A.Campbell. Structural Basis For Backtracking By the Sars-Cov-2 Replication-Transcription Complex Proc.Natl.Acad.Sci.Usa 2021.
ISSN: ESSN 1091-6490