Magnesium in PDB 7kx1: Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group

All present enzymatic activity of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group:
4.3.3.7;

The structure of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group, PDB code: 7kx1 was solved by S.Saran, D.A.R.Sanders, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	45.85 / 2.04
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	83.81, 230.1, 199.96, 90, 90, 90
R / Rfree (%)	21.4 / 25.4

The binding sites of Magnesium atom in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group (pdb code 7kx1). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group, PDB code: 7kx1:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg302 b:30.0 occ:1.00 OE1 A:GLU239 2.1 82.4 1.0 CD A:GLU239 3.0 79.0 1.0 CB A:GLU239 3.4 54.5 1.0 CG A:GLU239 3.7 67.6 1.0 CG A:LYS235 3.8 52.5 1.0 O A:LYS235 3.8 44.5 1.0 CE A:LYS235 3.8 61.3 1.0 OE2 A:GLU239 4.0 83.3 1.0 CD A:LYS235 4.0 60.1 1.0 C A:LYS235 4.5 42.6 1.0 CA A:GLU239 4.8 47.0 1.0 CA A:ILE236 4.9 34.9 1.0 N A:ILE236 5.0 39.4 1.0

Magnesium binding site 2 out of 2 in the Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Dihydrodipicolinate Synthase (Dhdps) From C.Jejuni, Y110F Mutant with Pyruvate Bound in the Active in C2221 Space Group within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg305 b:30.0 occ:1.00 OD2 B:ASP227 2.0 65.1 1.0 O B:HOH484 2.9 59.3 1.0 CG B:ASP227 3.0 60.4 1.0 OD1 B:ASP227 3.6 61.6 1.0 O B:HOH494 3.8 48.7 1.0 CB B:ASP227 4.3 53.2 1.0

S.Saran, D.A.R.Sanders. B-Factor Analysis Suggest That L-Lysine and R, R-Bislysine Allosterically Inhibit Cj.Dhdps Enzyme By Decreasing Protein Dynamics To Be Published.