Magnesium in PDB 7l6t: Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions.

The structure of Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions., PDB code: 7l6t was solved by G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, J.S.Brunzelle, K.J.F.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.33 / 1.78
Space group	P 31 2 1
Cell size a, b, c (Å), α, β, γ (°)	169.351, 169.351, 52.629, 90, 90, 120
R / Rfree (%)	14.1 / 16.2

The structure of Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions. also contains other interesting chemical elements:

Chlorine	(Cl)	1 atom
Zinc	(Zn)	2 atoms

The binding sites of Magnesium atom in the Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions. (pdb code 7l6t). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions., PDB code: 7l6t:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg7101 b:20.5 occ:1.00 O A:HOH7388 2.1 19.1 1.0 O C:HOH205 2.1 19.0 1.0 O A:HOH7455 2.1 20.1 1.0 OD1 A:ASN6996 2.1 18.4 1.0 O C:HOH219 2.1 22.1 1.0 O C:HOH206 2.2 19.5 1.0 CG A:ASN6996 3.1 18.4 1.0 ND2 A:ASN6996 3.6 17.5 1.0 O A:HOH7329 4.0 27.7 1.0 OP2 C:U2 4.1 20.9 1.0 O C:HOH211 4.2 26.1 1.0 OP1 C:U2 4.2 18.5 1.0 OG A:SER6998 4.2 19.1 1.0 O A:HOH7291 4.2 28.5 1.0 CB A:SER6999 4.3 17.9 1.0 O C:HOH220 4.4 35.9 1.0 O4' C:U3 4.4 25.5 1.0 OP1 C:A2M1 4.4 22.2 1.0 CB A:ASN6996 4.4 18.3 1.0 P C:U2 4.6 20.6 1.0 C1' C:U3 4.7 26.6 1.0 CA A:ASN6996 4.8 18.1 1.0 C4' C:U3 4.8 26.6 1.0 CE A:MET6840 4.9 29.9 1.0 O A:ASP6830 5.0 24.2 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions. within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg101 b:34.7 occ:1.00 OP1 C:U3 1.9 25.4 1.0 OP2 C:A4 2.1 36.7 1.0 O C:HOH212 2.1 32.8 1.0 O A:HOH7254 2.1 30.7 1.0 O A:HOH7370 2.2 28.1 1.0 O C:HOH215 2.2 38.2 1.0 P C:U3 3.3 25.0 1.0 P C:A4 3.5 39.0 1.0 OP2 C:U3 3.9 25.4 1.0 NZ A:LYS6874 4.0 29.8 1.0 O5' C:U3 4.1 24.4 1.0 OD2 A:ASP6873 4.1 34.3 1.0 O C:HOH217 4.2 40.1 1.0 O C:HOH223 4.2 36.8 1.0 O A:HOH7585 4.2 57.7 1.0 OP1 C:A4 4.2 41.4 1.0 O5' C:A4 4.3 40.7 1.0 O3' C:U2 4.4 23.1 1.0 C2' C:U2 4.4 23.9 1.0 C5' C:U3 4.4 24.9 1.0 OD1 A:ASP6873 4.5 31.0 1.0 O A:HOH7538 4.5 55.8 1.0 O3' C:U3 4.5 33.6 1.0 C3' C:U2 4.5 22.8 1.0 O2' C:U2 4.7 23.7 1.0 CG A:ASP6873 4.7 31.7 1.0 C3' C:U3 4.8 28.3 1.0

G.Minasov, L.Shuvalova, M.Rosas-Lemus, O.Kiryukhina, J.S.Brunzelle, K.J.F.Satchell, Center For Structural Genomics Of Infectious Diseases(Csgid). Crystal Structure of Sars-Cov-2 NSP16/10 Heterodimer in Complex with (M7GPPPA2M)Pupupapapa (Cap-1), S-Adenosyl-L-Homocysteine (Sah) and Two Magnesium (Mg) Ions. To Be Published.