Magnesium in PDB 7la4: Integrin ALPHAIIBBETA3-PT25-2 Complex

The structure of Integrin ALPHAIIBBETA3-PT25-2 Complex also contains other interesting chemical elements:

Calcium

(Ca)

6 atoms

The binding sites of Magnesium atom in the Integrin ALPHAIIBBETA3-PT25-2 Complex (pdb code 7la4). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Integrin ALPHAIIBBETA3-PT25-2 Complex, PDB code: 7la4:

Magnesium binding site 1 out of 1 in the Integrin ALPHAIIBBETA3-PT25-2 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Integrin ALPHAIIBBETA3-PT25-2 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg2001 b:38.1 occ:1.00 OE2 B:GLU220 2.1 33.7 1.0 CB B:SER121 2.5 41.3 1.0 OG B:SER121 2.7 41.3 1.0 OG B:SER123 3.0 45.5 1.0 CD B:GLU220 3.1 33.7 1.0 OE1 B:GLU220 3.5 33.7 1.0 OD1 B:ASP251 3.9 37.0 1.0 CA B:SER121 4.0 41.3 1.0 OD1 B:ASN215 4.1 39.5 1.0 CB B:SER123 4.2 45.5 1.0 CG B:GLU220 4.2 33.7 1.0 ND2 B:ASN215 4.4 39.5 1.0 OD1 B:ASP119 4.5 36.9 1.0 O B:ALA218 4.5 33.5 1.0 N B:SER123 4.6 45.5 1.0 CG B:ASN215 4.6 39.5 1.0 C B:SER121 4.6 41.3 1.0 N B:TYR122 4.7 45.6 1.0 N B:SER121 4.8 41.3 1.0 OD2 B:ASP119 4.8 36.9 1.0 CG B:ASP251 4.8 37.0 1.0 OD2 B:ASP251 4.9 37.0 1.0 CB B:ALA252 4.9 32.7 1.0 CG B:ASP119 5.0 36.9 1.0 CA B:SER123 5.0 45.5 1.0

D.Nesic, M.Bush, A.Spasic, J.Li, T.Kamata, M.Handa, M.Filizola, T.Walz, B.S.Coller. Electron Microscopy Shows That Binding of Monoclonal Antibody PT25-2 Primes Integrin Alpha Iib Beta 3 For Ligand Binding. Blood Adv V. 5 1781 2021.
ISSN: ESSN 2473-9537
PubMed: 33760023
DOI: 10.1182/BLOODADVANCES.2020004166