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Atomistry » Magnesium » PDB 7m88-7mig » 7mdp » |
Magnesium in PDB 7mdp: Kras G12C in Complex with G-2897Enzymatic activity of Kras G12C in Complex with G-2897
All present enzymatic activity of Kras G12C in Complex with G-2897:
3.6.5.2; Protein crystallography data
The structure of Kras G12C in Complex with G-2897, PDB code: 7mdp
was solved by
A.Oh,
Y.Frank,
W.Wang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 7mdp:
The structure of Kras G12C in Complex with G-2897 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Kras G12C in Complex with G-2897
(pdb code 7mdp). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Kras G12C in Complex with G-2897, PDB code: 7mdp: Magnesium binding site 1 out of 1 in 7mdpGo back to Magnesium Binding Sites List in 7mdp
Magnesium binding site 1 out
of 1 in the Kras G12C in Complex with G-2897
Mono view Stereo pair view
Reference:
C.W.Davies,
A.J.Oh,
R.Mroue,
M.Steffek,
J.M.Bruning,
Y.Xiao,
S.Feng,
S.Jayakar,
E.Chan,
V.Arumugam,
S.C.Uribe,
J.Drummond,
A.Frommlet,
C.Lu,
Y.Franke,
M.Merchant,
H.Koeppen,
J.G.Quinn,
S.Malhotra,
S.Do,
L.Gazzard,
H.E.Purkey,
J.Rudolph,
M.M.Mulvihill,
J.T.Koerber,
W.Wang,
M.Evangelista.
Conformation-Locking Antibodies For the Discovery and Characterization of Kras Inhibitors. Nat.Biotechnol. V. 40 769 2022.
Page generated: Thu Oct 3 00:51:16 2024
ISSN: ISSN 1087-0156 PubMed: 34992247 DOI: 10.1038/S41587-021-01126-9 |
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