Magnesium in PDB 7mf3: Structure of the Autoinhibited State of Smooth Muscle Myosin-2

The binding sites of Magnesium atom in the Structure of the Autoinhibited State of Smooth Muscle Myosin-2 (pdb code 7mf3). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of the Autoinhibited State of Smooth Muscle Myosin-2, PDB code: 7mf3:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Structure of the Autoinhibited State of Smooth Muscle Myosin-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Autoinhibited State of Smooth Muscle Myosin-2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2003 b:106.9 occ:1.00 CB A:SER246 2.1 100.2 1.0 O1B A:ADP2001 2.2 93.5 1.0 OG A:SER246 2.3 100.2 1.0 OG1 A:THR184 2.4 85.8 1.0 O3 A:PO42002 3.1 116.6 1.0 PB A:ADP2001 3.1 93.5 1.0 O4 A:PO42002 3.3 116.6 1.0 CA A:SER246 3.4 100.2 1.0 O2B A:ADP2001 3.5 93.5 1.0 O3B A:ADP2001 3.6 93.5 1.0 CB A:THR184 3.6 85.8 1.0 N A:SER246 3.7 100.2 1.0 P A:PO42002 3.8 116.6 1.0 O A:SER246 4.0 100.2 1.0 C A:SER246 4.2 100.2 1.0 O2 A:PO42002 4.3 116.6 1.0 CG2 A:THR184 4.5 85.8 1.0 O3A A:ADP2001 4.5 93.5 1.0 N A:THR184 4.6 85.8 1.0 CA A:THR184 4.7 85.8 1.0 CG A:LYS183 4.8 93.6 1.0 O2A A:ADP2001 4.9 93.5 1.0

Magnesium binding site 2 out of 4 in the Structure of the Autoinhibited State of Smooth Muscle Myosin-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Autoinhibited State of Smooth Muscle Myosin-2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg2003 b:103.0 occ:1.00 OG B:SER246 2.4 103.9 1.0 O3B B:ADP2001 2.6 125.9 1.0 CB B:SER246 2.7 103.9 1.0 O2B B:ADP2001 2.9 125.9 1.0 PB B:ADP2001 3.2 125.9 1.0 OG1 B:THR184 3.2 110.7 1.0 O3 B:PO42002 3.3 116.5 1.0 O3A B:ADP2001 3.7 125.9 1.0 CB B:LYS183 3.9 101.8 1.0 CA B:SER246 4.1 103.9 1.0 N B:SER246 4.3 103.9 1.0 O B:LYS183 4.5 101.8 1.0 C B:LYS183 4.6 101.8 1.0 P B:PO42002 4.6 116.5 1.0 O1B B:ADP2001 4.6 125.9 1.0 C B:SER245 4.6 113.8 1.0 CB B:THR184 4.6 110.7 1.0 CG B:LYS183 4.7 101.8 1.0 O B:SER245 4.8 113.8 1.0 CA B:LYS183 4.8 101.8 1.0 O2 B:PO42002 4.8 116.5 1.0 O B:ILE466 4.9 87.2 1.0 CA B:GLY180 4.9 90.2 1.0 O4 B:PO42002 4.9 116.5 1.0 N B:THR184 5.0 110.7 1.0

Magnesium binding site 3 out of 4 in the Structure of the Autoinhibited State of Smooth Muscle Myosin-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of the Autoinhibited State of Smooth Muscle Myosin-2 within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg200 b:197.8 occ:1.00 OD1 D:ASP45 2.4 191.0 1.0 OD2 D:ASP52 2.5 193.4 1.0 O D:PHE47 2.6 198.2 1.0 OD2 D:ASP49 2.7 193.0 1.0 CB D:ASN43 2.8 188.1 1.0 CG D:ASP45 3.0 191.0 1.0 OD1 D:ASP52 3.2 193.4 1.0 ND2 D:ASN43 3.2 188.1 1.0 CG D:ASP52 3.2 193.4 1.0 CG D:ASP49 3.3 193.0 1.0 OD2 D:ASP45 3.3 191.0 1.0 CG D:ASN43 3.5 188.1 1.0 C D:PHE47 3.7 198.2 1.0 OD1 D:ASP49 3.9 193.0 1.0 CA D:ASN43 3.9 188.1 1.0 CB D:ASP49 4.0 193.0 1.0 CB D:ASP45 4.2 191.0 1.0 N D:ASP45 4.2 191.0 1.0 N D:ASN43 4.3 188.1 1.0 N D:ARG44 4.3 186.3 1.0 C D:ASN43 4.3 188.1 1.0 C D:ILE48 4.4 195.5 1.0 O D:ILE48 4.5 195.5 1.0 N D:PHE47 4.5 198.2 1.0 CG D:ASP41 4.5 190.9 1.0 CA D:PHE47 4.6 198.2 1.0 N D:ASP49 4.6 193.0 1.0 OD2 D:ASP41 4.6 190.9 1.0 OD1 D:ASP41 4.6 190.9 1.0 CA D:ILE48 4.7 195.5 1.0 N D:ILE48 4.7 195.5 1.0 CB D:ASP52 4.7 193.4 1.0 OD1 D:ASN43 4.7 188.1 1.0 CA D:ASP45 4.8 191.0 1.0 CB D:PHE47 4.9 198.2 1.0 CA D:ASP49 4.9 193.0 1.0 CB D:ASP41 5.0 190.9 1.0

Magnesium binding site 4 out of 4 in the Structure of the Autoinhibited State of Smooth Muscle Myosin-2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of the Autoinhibited State of Smooth Muscle Myosin-2 within 5.0Å range: probe atom residue distance (Å) B Occ E:Mg200 b:197.2 occ:1.00 OD1 E:ASP41 2.1 207.5 1.0 OD1 E:ASP45 2.1 204.3 1.0 CG E:ASP45 2.4 204.3 1.0 OD2 E:ASP45 2.4 204.3 1.0 CG E:ASP41 2.7 207.5 1.0 OD1 E:ASN43 3.0 212.3 1.0 OD2 E:ASP41 3.3 207.5 1.0 CB E:ASP41 3.5 207.5 1.0 CA E:ASP41 3.5 207.5 1.0 O E:PHE47 3.5 202.4 1.0 OD2 E:ASP52 3.6 208.6 1.0 CB E:ASP45 3.7 204.3 1.0 CG E:ASN43 4.0 212.3 1.0 N E:ASP45 4.0 204.3 1.0 N E:GLY46 4.2 199.6 1.0 ND2 E:ASN43 4.3 212.3 1.0 CG E:ASP52 4.3 208.6 1.0 CA E:ASP45 4.3 204.3 1.0 C E:ASP41 4.4 207.5 1.0 C E:PHE47 4.5 202.4 1.0 CB E:ASP52 4.5 208.6 1.0 N E:PHE47 4.6 202.4 1.0 N E:ASP41 4.6 207.5 1.0 O E:ILE40 4.7 211.2 1.0 C E:ASP45 4.7 204.3 1.0 N E:GLN42 4.8 195.9 1.0 N E:ARG44 4.8 198.1 1.0 OD2 E:ASP49 4.9 218.3 1.0

S.M.Heissler, A.S.Arora, N.Billington, J.R.Sellers, K.Chinthalapudi. Cryo-Em Structure of the Autoinhibited State of Myosin-2. Sci Adv V. 7 K3273 2021.
ISSN: ESSN 2375-2548
PubMed: 34936462
DOI: 10.1126/SCIADV.ABK3273