Magnesium in PDB 7mhs: Structure of P97 (Subunits A to E) with Substrate Engaged
Enzymatic activity of Structure of P97 (Subunits A to E) with Substrate Engaged
All present enzymatic activity of Structure of P97 (Subunits A to E) with Substrate Engaged:
3.6.4.6;
Other elements in 7mhs:
The structure of Structure of P97 (Subunits A to E) with Substrate Engaged also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Structure of P97 (Subunits A to E) with Substrate Engaged
(pdb code 7mhs). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 8 binding sites of Magnesium where determined in the
Structure of P97 (Subunits A to E) with Substrate Engaged, PDB code: 7mhs:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
6;
7;
8;
Magnesium binding site 1 out
of 8 in 7mhs
Go back to
Magnesium Binding Sites List in 7mhs
Magnesium binding site 1 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg903
b:48.3
occ:1.00
|
F1
|
A:BEF902
|
2.0
|
48.3
|
1.0
|
O2B
|
A:ADP901
|
2.0
|
48.3
|
1.0
|
O3B
|
A:ADP901
|
2.5
|
48.3
|
1.0
|
PB
|
A:ADP901
|
2.6
|
48.3
|
1.0
|
OG1
|
A:THR525
|
2.9
|
53.0
|
1.0
|
BE
|
A:BEF902
|
3.2
|
48.3
|
1.0
|
O1B
|
A:ADP901
|
3.3
|
48.3
|
1.0
|
OD1
|
A:ASP577
|
3.9
|
50.5
|
1.0
|
O3A
|
A:ADP901
|
4.1
|
48.3
|
1.0
|
CE
|
A:LYS524
|
4.1
|
48.2
|
1.0
|
F3
|
A:BEF902
|
4.2
|
48.3
|
1.0
|
F2
|
A:BEF902
|
4.2
|
48.3
|
1.0
|
OE2
|
A:GLU578
|
4.3
|
47.1
|
1.0
|
CB
|
A:THR525
|
4.3
|
53.0
|
1.0
|
NZ
|
A:LYS524
|
4.4
|
48.2
|
1.0
|
OD2
|
A:ASP577
|
4.5
|
50.5
|
1.0
|
N
|
A:THR525
|
4.6
|
53.0
|
1.0
|
CG
|
A:ASP577
|
4.7
|
50.5
|
1.0
|
CB
|
A:LYS524
|
4.8
|
48.2
|
1.0
|
CA
|
A:THR525
|
4.9
|
53.0
|
1.0
|
|
Magnesium binding site 2 out
of 8 in 7mhs
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Magnesium Binding Sites List in 7mhs
Magnesium binding site 2 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg906
b:69.3
occ:1.00
|
F1
|
A:BEF905
|
2.0
|
69.3
|
1.0
|
O2B
|
A:ADP904
|
2.0
|
69.3
|
1.0
|
PB
|
A:ADP904
|
2.8
|
69.3
|
1.0
|
OG1
|
A:THR252
|
3.0
|
78.7
|
1.0
|
O3B
|
A:ADP904
|
3.1
|
69.3
|
1.0
|
BE
|
A:BEF905
|
3.2
|
69.3
|
1.0
|
O1B
|
A:ADP904
|
3.3
|
69.3
|
1.0
|
OE2
|
A:GLU305
|
3.8
|
70.5
|
1.0
|
NH2
|
B:ARG362
|
3.8
|
45.4
|
1.0
|
F3
|
A:BEF905
|
4.2
|
69.3
|
1.0
|
F2
|
A:BEF905
|
4.2
|
69.3
|
1.0
|
CB
|
A:THR252
|
4.3
|
78.7
|
1.0
|
O3A
|
A:ADP904
|
4.3
|
69.3
|
1.0
|
CG
|
A:LYS251
|
4.5
|
73.7
|
1.0
|
CD
|
A:LYS251
|
4.5
|
73.7
|
1.0
|
O
|
B:ASP333
|
4.6
|
52.2
|
1.0
|
NH2
|
B:ARG359
|
4.9
|
52.7
|
1.0
|
|
Magnesium binding site 3 out
of 8 in 7mhs
Go back to
Magnesium Binding Sites List in 7mhs
Magnesium binding site 3 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg903
b:20.3
occ:1.00
|
F1
|
B:BEF902
|
2.0
|
20.3
|
1.0
|
O2B
|
B:ADP901
|
2.0
|
20.3
|
1.0
|
OG1
|
B:THR525
|
3.0
|
21.3
|
1.0
|
PB
|
B:ADP901
|
3.0
|
20.3
|
1.0
|
BE
|
B:BEF902
|
3.2
|
20.3
|
1.0
|
O3B
|
B:ADP901
|
3.3
|
20.3
|
1.0
|
O1B
|
B:ADP901
|
3.5
|
20.3
|
1.0
|
OE2
|
B:GLU578
|
3.9
|
23.5
|
1.0
|
F3
|
B:BEF902
|
4.0
|
20.3
|
1.0
|
NH2
|
C:ARG638
|
4.1
|
20.4
|
1.0
|
CB
|
B:THR525
|
4.2
|
21.3
|
1.0
|
O
|
C:ASP609
|
4.2
|
20.1
|
1.0
|
F2
|
B:BEF902
|
4.4
|
20.3
|
1.0
|
O3A
|
B:ADP901
|
4.4
|
20.3
|
1.0
|
OD1
|
B:ASP577
|
4.5
|
24.0
|
1.0
|
OD2
|
B:ASP577
|
4.7
|
24.0
|
1.0
|
CE
|
B:LYS524
|
4.9
|
20.4
|
1.0
|
NZ
|
B:LYS524
|
4.9
|
20.4
|
1.0
|
N
|
B:THR525
|
4.9
|
21.3
|
1.0
|
|
Magnesium binding site 4 out
of 8 in 7mhs
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Magnesium Binding Sites List in 7mhs
Magnesium binding site 4 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg906
b:24.9
occ:1.00
|
O2B
|
B:ADP904
|
2.0
|
24.9
|
1.0
|
F1
|
B:BEF905
|
2.0
|
24.9
|
1.0
|
OG1
|
B:THR252
|
2.9
|
26.4
|
1.0
|
PB
|
B:ADP904
|
2.9
|
24.9
|
1.0
|
BE
|
B:BEF905
|
3.2
|
24.9
|
1.0
|
O1B
|
B:ADP904
|
3.3
|
24.9
|
1.0
|
O3B
|
B:ADP904
|
3.4
|
24.9
|
1.0
|
NH2
|
C:ARG362
|
3.7
|
22.4
|
1.0
|
CB
|
B:THR252
|
4.1
|
26.4
|
1.0
|
F3
|
B:BEF905
|
4.2
|
24.9
|
1.0
|
F2
|
B:BEF905
|
4.3
|
24.9
|
1.0
|
OD1
|
B:ASP304
|
4.3
|
33.3
|
1.0
|
O3A
|
B:ADP904
|
4.4
|
24.9
|
1.0
|
OD2
|
B:ASP304
|
4.5
|
33.3
|
1.0
|
OE2
|
B:GLU305
|
4.6
|
31.4
|
1.0
|
CG
|
B:ASP304
|
4.9
|
33.3
|
1.0
|
N
|
B:THR252
|
4.9
|
26.4
|
1.0
|
CG2
|
B:THR252
|
5.0
|
26.4
|
1.0
|
CZ
|
C:ARG362
|
5.0
|
22.4
|
1.0
|
|
Magnesium binding site 5 out
of 8 in 7mhs
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Magnesium Binding Sites List in 7mhs
Magnesium binding site 5 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg903
b:21.1
occ:1.00
|
F1
|
C:BEF902
|
2.0
|
21.1
|
1.0
|
O2B
|
C:ADP901
|
2.0
|
21.1
|
1.0
|
OG1
|
C:THR525
|
2.9
|
20.4
|
1.0
|
PB
|
C:ADP901
|
3.0
|
21.1
|
1.0
|
BE
|
C:BEF902
|
3.2
|
21.1
|
1.0
|
O3B
|
C:ADP901
|
3.3
|
21.1
|
1.0
|
O1B
|
C:ADP901
|
3.3
|
21.1
|
1.0
|
NH2
|
D:ARG638
|
3.5
|
20.4
|
1.0
|
O
|
D:ASP609
|
3.8
|
21.9
|
1.0
|
F3
|
C:BEF902
|
4.1
|
21.1
|
1.0
|
CB
|
C:THR525
|
4.1
|
20.4
|
1.0
|
F2
|
C:BEF902
|
4.3
|
21.1
|
1.0
|
O3A
|
C:ADP901
|
4.4
|
21.1
|
1.0
|
OD1
|
C:ASP577
|
4.4
|
20.8
|
1.0
|
OD2
|
C:ASP577
|
4.5
|
20.8
|
1.0
|
OE2
|
C:GLU578
|
4.8
|
21.0
|
1.0
|
CZ
|
D:ARG638
|
4.8
|
20.4
|
1.0
|
O1A
|
C:ADP901
|
4.8
|
21.1
|
1.0
|
CG2
|
C:THR525
|
4.8
|
20.4
|
1.0
|
CG
|
C:ASP577
|
4.9
|
20.8
|
1.0
|
|
Magnesium binding site 6 out
of 8 in 7mhs
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Magnesium Binding Sites List in 7mhs
Magnesium binding site 6 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 6 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg906
b:21.2
occ:1.00
|
F1
|
C:BEF905
|
2.0
|
21.2
|
1.0
|
O2B
|
C:ADP904
|
2.0
|
21.2
|
1.0
|
OG1
|
C:THR252
|
2.1
|
19.0
|
1.0
|
PB
|
C:ADP904
|
3.1
|
21.2
|
1.0
|
BE
|
C:BEF905
|
3.2
|
21.2
|
1.0
|
CB
|
C:THR252
|
3.2
|
19.0
|
1.0
|
O3B
|
C:ADP904
|
3.4
|
21.2
|
1.0
|
CG2
|
C:THR252
|
3.8
|
19.0
|
1.0
|
OD2
|
C:ASP304
|
3.9
|
23.8
|
1.0
|
O1B
|
C:ADP904
|
3.9
|
21.2
|
1.0
|
F3
|
C:BEF905
|
4.0
|
21.2
|
1.0
|
NH2
|
D:ARG362
|
4.1
|
20.9
|
1.0
|
F2
|
C:BEF905
|
4.4
|
21.2
|
1.0
|
O3A
|
C:ADP904
|
4.4
|
21.2
|
1.0
|
CA
|
C:THR252
|
4.4
|
19.0
|
1.0
|
OD1
|
C:ASP304
|
4.6
|
23.8
|
1.0
|
N
|
C:THR252
|
4.6
|
19.0
|
1.0
|
CG
|
C:ASP304
|
4.6
|
23.8
|
1.0
|
O1A
|
C:ADP904
|
5.0
|
21.2
|
1.0
|
OE2
|
C:GLU305
|
5.0
|
22.1
|
1.0
|
|
Magnesium binding site 7 out
of 8 in 7mhs
Go back to
Magnesium Binding Sites List in 7mhs
Magnesium binding site 7 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 7 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg903
b:39.6
occ:1.00
|
F1
|
D:BEF902
|
2.0
|
39.6
|
1.0
|
O2B
|
D:ADP901
|
2.0
|
39.6
|
1.0
|
OG1
|
D:THR525
|
2.7
|
35.0
|
1.0
|
PB
|
D:ADP901
|
2.9
|
39.6
|
1.0
|
BE
|
D:BEF902
|
3.2
|
39.6
|
1.0
|
O1B
|
D:ADP901
|
3.3
|
39.6
|
1.0
|
O3B
|
D:ADP901
|
3.3
|
39.6
|
1.0
|
CB
|
D:THR525
|
3.9
|
35.0
|
1.0
|
NH2
|
E:ARG638
|
4.1
|
45.7
|
1.0
|
F2
|
D:BEF902
|
4.1
|
39.6
|
1.0
|
OE2
|
D:GLU578
|
4.2
|
28.9
|
1.0
|
F3
|
D:BEF902
|
4.3
|
39.6
|
1.0
|
OD1
|
D:ASP577
|
4.3
|
29.1
|
1.0
|
O
|
E:ASP609
|
4.4
|
45.6
|
1.0
|
O3A
|
D:ADP901
|
4.4
|
39.6
|
1.0
|
NZ
|
D:LYS524
|
4.5
|
30.6
|
1.0
|
N
|
D:THR525
|
4.6
|
35.0
|
1.0
|
CE
|
D:LYS524
|
4.7
|
30.6
|
1.0
|
OD2
|
D:ASP577
|
4.8
|
29.1
|
1.0
|
CA
|
D:THR525
|
4.8
|
35.0
|
1.0
|
CG2
|
D:THR525
|
4.9
|
35.0
|
1.0
|
|
Magnesium binding site 8 out
of 8 in 7mhs
Go back to
Magnesium Binding Sites List in 7mhs
Magnesium binding site 8 out
of 8 in the Structure of P97 (Subunits A to E) with Substrate Engaged
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 8 of Structure of P97 (Subunits A to E) with Substrate Engaged within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg906
b:30.6
occ:1.00
|
F1
|
D:BEF905
|
2.0
|
30.6
|
1.0
|
O2B
|
D:ADP904
|
2.0
|
30.6
|
1.0
|
PB
|
D:ADP904
|
2.9
|
30.6
|
1.0
|
OG1
|
D:THR252
|
3.0
|
25.4
|
1.0
|
BE
|
D:BEF905
|
3.2
|
30.6
|
1.0
|
O1B
|
D:ADP904
|
3.3
|
30.6
|
1.0
|
O3B
|
D:ADP904
|
3.4
|
30.6
|
1.0
|
OE2
|
D:GLU305
|
3.9
|
31.4
|
1.0
|
NH2
|
E:ARG362
|
3.9
|
51.5
|
1.0
|
OD2
|
D:ASP304
|
3.9
|
30.0
|
1.0
|
F3
|
D:BEF905
|
4.1
|
30.6
|
1.0
|
CB
|
D:THR252
|
4.2
|
25.4
|
1.0
|
F2
|
D:BEF905
|
4.3
|
30.6
|
1.0
|
OD1
|
D:ASP304
|
4.4
|
30.0
|
1.0
|
O3A
|
D:ADP904
|
4.4
|
30.6
|
1.0
|
CG
|
D:ASP304
|
4.6
|
30.0
|
1.0
|
O
|
E:ASP333
|
4.8
|
56.6
|
1.0
|
CG2
|
D:THR252
|
5.0
|
25.4
|
1.0
|
|
Reference:
Y.Xu,
H.Han,
I.Cooney,
Y.Guo,
N.G.Moran,
N.R.Zuniga,
J.C.Price,
C.P.Hill,
P.S.Shen.
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ISSN: ESSN 2041-1723
PubMed: 35552390
DOI: 10.1038/S41467-022-30318-3
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