Magnesium in PDB 7nfy: P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
Enzymatic activity of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
All present enzymatic activity of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs:
3.4.21.53;
Magnesium Binding Sites:
The binding sites of Magnesium atom in the P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
(pdb code 7nfy). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 5 binding sites of Magnesium where determined in the
P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs, PDB code: 7nfy:
Jump to Magnesium binding site number:
1;
2;
3;
4;
5;
Magnesium binding site 1 out
of 5 in 7nfy
Go back to
Magnesium Binding Sites List in 7nfy
Magnesium binding site 1 out
of 5 in the P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1002
b:97.1
occ:1.00
|
OG1
|
A:THR530
|
2.1
|
111.2
|
1.0
|
O1B
|
A:AGS1001
|
2.1
|
105.3
|
1.0
|
O2G
|
A:AGS1001
|
2.1
|
105.3
|
1.0
|
HB
|
A:THR530
|
2.7
|
111.2
|
1.0
|
CB
|
A:THR530
|
2.9
|
111.2
|
1.0
|
HH12
|
B:ARG652
|
2.9
|
102.0
|
1.0
|
PG
|
A:AGS1001
|
2.9
|
105.3
|
1.0
|
S1G
|
A:AGS1001
|
2.9
|
105.3
|
1.0
|
PB
|
A:AGS1001
|
3.3
|
105.3
|
1.0
|
HG21
|
A:THR530
|
3.4
|
111.2
|
1.0
|
O1A
|
A:AGS1001
|
3.5
|
105.3
|
1.0
|
O3B
|
A:AGS1001
|
3.5
|
105.3
|
1.0
|
H
|
A:THR530
|
3.6
|
111.2
|
1.0
|
NH1
|
B:ARG652
|
3.7
|
102.0
|
1.0
|
CG2
|
A:THR530
|
3.7
|
111.2
|
1.0
|
HH12
|
A:ARG710
|
3.8
|
102.4
|
1.0
|
HH11
|
B:ARG652
|
4.0
|
102.0
|
1.0
|
CA
|
A:THR530
|
4.1
|
111.2
|
1.0
|
N
|
A:THR530
|
4.2
|
111.2
|
1.0
|
PA
|
A:AGS1001
|
4.2
|
105.3
|
1.0
|
HZ2
|
A:LYS529
|
4.2
|
109.1
|
1.0
|
HH22
|
B:ARG652
|
4.3
|
102.0
|
1.0
|
O3G
|
A:AGS1001
|
4.3
|
105.3
|
1.0
|
HG22
|
A:THR530
|
4.3
|
111.2
|
1.0
|
O3A
|
A:AGS1001
|
4.3
|
105.3
|
1.0
|
O2B
|
A:AGS1001
|
4.3
|
105.3
|
1.0
|
O2A
|
A:AGS1001
|
4.4
|
105.3
|
1.0
|
HG23
|
A:THR530
|
4.4
|
111.2
|
1.0
|
HA
|
A:THR530
|
4.5
|
111.2
|
1.0
|
NH1
|
A:ARG710
|
4.6
|
102.4
|
1.0
|
OD1
|
A:ASP590
|
4.6
|
113.6
|
1.0
|
HZ3
|
A:LYS529
|
4.6
|
109.1
|
1.0
|
HH11
|
A:ARG710
|
4.6
|
102.4
|
1.0
|
CZ
|
B:ARG652
|
4.7
|
102.0
|
1.0
|
HG1
|
A:THR638
|
4.8
|
111.0
|
1.0
|
OD2
|
A:ASP590
|
4.8
|
113.6
|
1.0
|
HB2
|
A:LYS529
|
4.8
|
109.1
|
1.0
|
NH2
|
B:ARG652
|
4.9
|
102.0
|
1.0
|
NZ
|
A:LYS529
|
4.9
|
109.1
|
1.0
|
H
|
A:GLY526
|
5.0
|
114.2
|
1.0
|
|
Magnesium binding site 2 out
of 5 in 7nfy
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Magnesium Binding Sites List in 7nfy
Magnesium binding site 2 out
of 5 in the P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg1002
b:70.3
occ:1.00
|
OG1
|
B:THR530
|
2.1
|
88.4
|
1.0
|
O1B
|
B:AGS1001
|
2.1
|
103.3
|
1.0
|
O2G
|
B:AGS1001
|
2.1
|
103.3
|
1.0
|
S1G
|
B:AGS1001
|
2.9
|
103.3
|
1.0
|
PG
|
B:AGS1001
|
2.9
|
103.3
|
1.0
|
HB
|
B:THR530
|
2.9
|
88.4
|
1.0
|
CB
|
B:THR530
|
3.0
|
88.4
|
1.0
|
PB
|
B:AGS1001
|
3.2
|
103.3
|
1.0
|
O1A
|
B:AGS1001
|
3.3
|
103.3
|
1.0
|
HH22
|
C:ARG652
|
3.4
|
86.2
|
1.0
|
H
|
B:THR530
|
3.5
|
88.4
|
1.0
|
O3B
|
B:AGS1001
|
3.5
|
103.3
|
1.0
|
HG21
|
B:THR530
|
3.6
|
88.4
|
1.0
|
OE2
|
B:GLU591
|
3.8
|
92.2
|
1.0
|
CG2
|
B:THR530
|
3.9
|
88.4
|
1.0
|
PA
|
B:AGS1001
|
4.0
|
103.3
|
1.0
|
O3A
|
B:AGS1001
|
4.0
|
103.3
|
1.0
|
N
|
B:THR530
|
4.1
|
88.4
|
1.0
|
HZ3
|
B:LYS529
|
4.2
|
91.6
|
1.0
|
CA
|
B:THR530
|
4.2
|
88.4
|
1.0
|
NH2
|
C:ARG652
|
4.2
|
86.2
|
1.0
|
O2A
|
B:AGS1001
|
4.2
|
103.3
|
1.0
|
O3G
|
B:AGS1001
|
4.2
|
103.3
|
1.0
|
HH12
|
C:ARG652
|
4.2
|
86.2
|
1.0
|
HH22
|
B:ARG710
|
4.3
|
89.5
|
1.0
|
HZ1
|
B:LYS529
|
4.4
|
91.6
|
1.0
|
O2B
|
B:AGS1001
|
4.5
|
103.3
|
1.0
|
HB2
|
B:LYS529
|
4.5
|
91.6
|
1.0
|
HG23
|
B:THR530
|
4.5
|
88.4
|
1.0
|
HG1
|
B:THR638
|
4.6
|
90.0
|
1.0
|
HG22
|
B:THR530
|
4.6
|
88.4
|
1.0
|
HH21
|
C:ARG652
|
4.6
|
86.2
|
1.0
|
HA
|
B:THR530
|
4.6
|
88.4
|
1.0
|
NZ
|
B:LYS529
|
4.7
|
91.6
|
1.0
|
NH2
|
B:ARG710
|
4.8
|
89.5
|
1.0
|
HH21
|
B:ARG710
|
4.8
|
89.5
|
1.0
|
HE2
|
B:LYS529
|
4.8
|
91.6
|
1.0
|
CD
|
B:GLU591
|
4.9
|
92.2
|
1.0
|
NH1
|
C:ARG652
|
4.9
|
86.2
|
1.0
|
OD1
|
B:ASP590
|
4.9
|
90.5
|
1.0
|
OD2
|
B:ASP590
|
5.0
|
90.5
|
1.0
|
|
Magnesium binding site 3 out
of 5 in 7nfy
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Magnesium Binding Sites List in 7nfy
Magnesium binding site 3 out
of 5 in the P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg1002
b:105.5
occ:1.00
|
OG1
|
C:THR530
|
2.1
|
89.0
|
1.0
|
O2G
|
C:AGS1001
|
2.1
|
119.9
|
1.0
|
O1B
|
C:AGS1001
|
2.1
|
119.9
|
1.0
|
S1G
|
C:AGS1001
|
2.7
|
119.9
|
1.0
|
PG
|
C:AGS1001
|
2.8
|
119.9
|
1.0
|
HB
|
C:THR530
|
2.8
|
89.0
|
1.0
|
CB
|
C:THR530
|
3.0
|
89.0
|
1.0
|
O1A
|
C:AGS1001
|
3.1
|
119.9
|
1.0
|
PB
|
C:AGS1001
|
3.3
|
119.9
|
1.0
|
H
|
C:THR530
|
3.4
|
89.0
|
1.0
|
O3B
|
C:AGS1001
|
3.4
|
119.9
|
1.0
|
HG21
|
C:THR530
|
3.6
|
89.0
|
1.0
|
PA
|
C:AGS1001
|
3.9
|
119.9
|
1.0
|
CG2
|
C:THR530
|
3.9
|
89.0
|
1.0
|
O2A
|
C:AGS1001
|
3.9
|
119.9
|
1.0
|
HH21
|
D:ARG652
|
4.1
|
98.1
|
1.0
|
N
|
C:THR530
|
4.1
|
89.0
|
1.0
|
O3A
|
C:AGS1001
|
4.1
|
119.9
|
1.0
|
O3G
|
C:AGS1001
|
4.1
|
119.9
|
1.0
|
HZ2
|
C:LYS529
|
4.1
|
94.5
|
1.0
|
CA
|
C:THR530
|
4.1
|
89.0
|
1.0
|
HH21
|
C:ARG710
|
4.3
|
97.4
|
1.0
|
HZ3
|
C:LYS529
|
4.3
|
94.5
|
1.0
|
HH22
|
D:ARG652
|
4.4
|
98.1
|
1.0
|
HG23
|
C:THR530
|
4.4
|
89.0
|
1.0
|
OD2
|
D:ASP612
|
4.5
|
93.8
|
1.0
|
O2B
|
C:AGS1001
|
4.5
|
119.9
|
1.0
|
HB2
|
C:LYS529
|
4.6
|
94.5
|
1.0
|
HG22
|
C:THR530
|
4.6
|
89.0
|
1.0
|
NH2
|
D:ARG652
|
4.6
|
98.1
|
1.0
|
NZ
|
C:LYS529
|
4.6
|
94.5
|
1.0
|
HA
|
C:THR530
|
4.7
|
89.0
|
1.0
|
OD1
|
C:ASP590
|
4.7
|
87.6
|
1.0
|
OE2
|
C:GLU591
|
4.7
|
92.4
|
1.0
|
HG1
|
C:THR638
|
4.8
|
87.8
|
1.0
|
HE2
|
C:LYS529
|
4.8
|
94.5
|
1.0
|
HH22
|
C:ARG710
|
4.8
|
97.4
|
1.0
|
NH2
|
C:ARG710
|
4.9
|
97.4
|
1.0
|
OD2
|
C:ASP590
|
4.9
|
87.6
|
1.0
|
|
Magnesium binding site 4 out
of 5 in 7nfy
Go back to
Magnesium Binding Sites List in 7nfy
Magnesium binding site 4 out
of 5 in the P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg1002
b:100.1
occ:1.00
|
OG1
|
D:THR530
|
2.1
|
84.9
|
1.0
|
O2G
|
D:AGS1001
|
2.1
|
95.6
|
1.0
|
O1B
|
D:AGS1001
|
2.1
|
95.6
|
1.0
|
PG
|
D:AGS1001
|
3.0
|
95.6
|
1.0
|
HB
|
D:THR530
|
3.1
|
84.9
|
1.0
|
CB
|
D:THR530
|
3.1
|
84.9
|
1.0
|
S1G
|
D:AGS1001
|
3.2
|
95.6
|
1.0
|
PB
|
D:AGS1001
|
3.3
|
95.6
|
1.0
|
O1A
|
D:AGS1001
|
3.3
|
95.6
|
1.0
|
H
|
D:THR530
|
3.4
|
84.9
|
1.0
|
O3B
|
D:AGS1001
|
3.5
|
95.6
|
1.0
|
HG21
|
D:THR530
|
3.8
|
84.9
|
1.0
|
CG2
|
D:THR530
|
4.0
|
84.9
|
1.0
|
N
|
D:THR530
|
4.1
|
84.9
|
1.0
|
PA
|
D:AGS1001
|
4.2
|
95.6
|
1.0
|
HZ1
|
D:LYS529
|
4.2
|
85.2
|
1.0
|
CA
|
D:THR530
|
4.2
|
84.9
|
1.0
|
O3A
|
D:AGS1001
|
4.3
|
95.6
|
1.0
|
O2A
|
D:AGS1001
|
4.4
|
95.6
|
1.0
|
HH21
|
E:ARG652
|
4.4
|
100.4
|
1.0
|
O2B
|
D:AGS1001
|
4.4
|
95.6
|
1.0
|
O3G
|
D:AGS1001
|
4.4
|
95.6
|
1.0
|
HB2
|
D:LYS529
|
4.4
|
85.2
|
1.0
|
HG23
|
D:THR530
|
4.5
|
84.9
|
1.0
|
HH22
|
E:ARG652
|
4.5
|
100.4
|
1.0
|
HG1
|
D:THR638
|
4.5
|
101.7
|
1.0
|
HE2
|
D:LYS529
|
4.6
|
85.2
|
1.0
|
NH2
|
E:ARG652
|
4.7
|
100.4
|
1.0
|
HZ2
|
D:LYS529
|
4.7
|
85.2
|
1.0
|
OD1
|
D:ASP590
|
4.7
|
106.4
|
1.0
|
HA
|
D:THR530
|
4.7
|
84.9
|
1.0
|
NZ
|
D:LYS529
|
4.8
|
85.2
|
1.0
|
HG22
|
D:THR530
|
4.8
|
84.9
|
1.0
|
HH21
|
D:ARG710
|
5.0
|
90.6
|
1.0
|
|
Magnesium binding site 5 out
of 5 in 7nfy
Go back to
Magnesium Binding Sites List in 7nfy
Magnesium binding site 5 out
of 5 in the P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 5 of P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
F:Mg1002
b:106.2
occ:1.00
|
OG1
|
F:THR530
|
2.1
|
107.0
|
1.0
|
O1B
|
F:AGS1001
|
2.1
|
103.4
|
1.0
|
O2G
|
F:AGS1001
|
2.1
|
103.4
|
1.0
|
PG
|
F:AGS1001
|
3.0
|
103.4
|
1.0
|
CB
|
F:THR530
|
3.2
|
107.0
|
1.0
|
HB
|
F:THR530
|
3.3
|
107.0
|
1.0
|
PB
|
F:AGS1001
|
3.3
|
103.4
|
1.0
|
O1A
|
F:AGS1001
|
3.3
|
103.4
|
1.0
|
S1G
|
F:AGS1001
|
3.3
|
103.4
|
1.0
|
H
|
F:THR530
|
3.4
|
107.0
|
1.0
|
O3B
|
F:AGS1001
|
3.5
|
103.4
|
1.0
|
HG21
|
F:THR530
|
3.9
|
107.0
|
1.0
|
O2A
|
F:AGS1001
|
3.9
|
103.4
|
1.0
|
PA
|
F:AGS1001
|
3.9
|
103.4
|
1.0
|
O3A
|
F:AGS1001
|
4.1
|
103.4
|
1.0
|
CG2
|
F:THR530
|
4.1
|
107.0
|
1.0
|
N
|
F:THR530
|
4.2
|
107.0
|
1.0
|
HB2
|
F:LYS529
|
4.2
|
110.3
|
1.0
|
OD1
|
F:ASP590
|
4.3
|
127.7
|
1.0
|
CA
|
F:THR530
|
4.3
|
107.0
|
1.0
|
OD2
|
F:ASP590
|
4.4
|
127.7
|
1.0
|
O3G
|
F:AGS1001
|
4.4
|
103.4
|
1.0
|
O2B
|
F:AGS1001
|
4.5
|
103.4
|
1.0
|
HG23
|
F:THR530
|
4.5
|
107.0
|
1.0
|
HA
|
F:THR530
|
4.8
|
107.0
|
1.0
|
CG
|
F:ASP590
|
4.8
|
127.7
|
1.0
|
HD2
|
F:LYS529
|
4.9
|
110.3
|
1.0
|
HH12
|
F:ARG546
|
4.9
|
120.1
|
1.0
|
HG22
|
F:THR530
|
4.9
|
107.0
|
1.0
|
|
Reference:
I.Mohammed,
K.A.Schmitz,
N.Schenck,
T.Maier,
J.P.Abrahams.
P1A-State of Wild Type Human Mitochondrial LONP1 Protease with Bound Substrate Protein and Atpgs To Be Published.
Page generated: Thu Oct 3 01:37:33 2024
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