Magnesium in PDB 7ni7: Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031

All present enzymatic activity of Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031:
2.1.1.348;

The structure of Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031, PDB code: 7ni7 was solved by R.K.Bedi, D.Huang, A.Caflisch, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	39.61 / 2.50
Space group	P 32 2 1
Cell size a, b, c (Å), α, β, γ (°)	64.14, 64.14, 225.97, 90, 90, 120
R / Rfree (%)	20.8 / 28.4

The binding sites of Magnesium atom in the Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031 (pdb code 7ni7). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031, PDB code: 7ni7:

Magnesium binding site 1 out of 1 in the Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg402 b:55.7 occ:1.00 NE2 B:HIS336 2.3 64.3 1.0 CE1 B:HIS336 2.4 53.4 1.0 OD1 B:ASP157 2.8 64.7 1.0 OD2 B:ASP157 3.3 71.4 1.0 CB B:HIS332 3.3 49.5 1.0 CG B:ASP157 3.5 66.2 1.0 CD2 B:HIS336 3.6 53.7 1.0 ND1 B:HIS336 3.6 53.0 1.0 CG B:HIS332 3.7 54.5 1.0 ND1 B:HIS332 4.0 60.5 1.0 CA B:HIS332 4.2 43.9 1.0 CG B:HIS336 4.3 53.7 1.0 CD2 B:HIS332 4.5 51.1 1.0 O B:HIS332 4.7 51.0 1.0 C B:HIS332 4.7 46.6 1.0 CE1 B:HIS332 4.9 62.8 1.0 CB B:ASP157 4.9 59.8 1.0

R.K.Bedi, D.Huang, A.Caflisch. Crystal Structure of the Human METTL3-METTL14 Complex with Compound UOZ031 To Be Published.