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Magnesium in PDB 7nwe: Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10
Enzymatic activity of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10
All present enzymatic activity of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10:
2.6.1.42;
2.6.1.42;
Protein crystallography data
The structure of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10, PDB code: 7nwe
was solved by
R.C.Hillig,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 47.78 / 2.54 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 66.49, 103.461, 107.749, 90, 90, 90 |
| R / Rfree (%) | 21.1 / 24.5 |
Other elements in 7nwe:
The structure of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10 also contains other interesting chemical elements:
| Fluorine | (F) | 6 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10
(pdb code 7nwe). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10, PDB code: 7nwe:
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10, PDB code: 7nwe:
Magnesium binding site 1 out of 1 in 7nwe
Go back to
Magnesium Binding Sites List in 7nwe
Magnesium binding site 1 out
of 1 in the Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Crystal Structure of Human Cytosolic Branched-Chain Aminotransferase (BCAT1) in Complex with Plp and Inhibitor Compound 10 within 5.0Å range:
|
Reference:
J.Gunther,
R.C.Hillig,
K.Zimmermann,
S.Kaulfuss,
C.Lemos,
D.Nguyen,
H.Rehwinkel,
M.Habgood,
C.Lechner,
R.Neuhaus,
U.Ganzer,
M.Drewes,
J.Chai,
L.Bouche.
Bay-069, A Novel (Trifluoromethyl)Pyrimidinedione-Based BCAT1/2 Inhibitor and Chemical Probe. J.Med.Chem. V. 65 14366 2022.
ISSN: ISSN 0022-2623
PubMed: 36261130
DOI: 10.1021/ACS.JMEDCHEM.2C00441
Page generated: Thu Oct 3 02:20:37 2024
ISSN: ISSN 0022-2623
PubMed: 36261130
DOI: 10.1021/ACS.JMEDCHEM.2C00441
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