Magnesium in PDB 7orn: La Crosse Virus Polymerase at Replication Initiation Stage

All present enzymatic activity of La Crosse Virus Polymerase at Replication Initiation Stage:
2.7.7.48;

The binding sites of Magnesium atom in the La Crosse Virus Polymerase at Replication Initiation Stage (pdb code 7orn). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the La Crosse Virus Polymerase at Replication Initiation Stage, PDB code: 7orn:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the La Crosse Virus Polymerase at Replication Initiation Stage


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of La Crosse Virus Polymerase at Replication Initiation Stage within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2302 b:9.9 occ:1.00 OD1 A:ASP1187 2.1 7.9 1.0 OD1 A:ASP1060 2.2 9.1 1.0 OD2 A:ASP1188 2.2 9.8 1.0 O2A A:ATP2301 2.3 7.6 1.0 CG A:ASP1188 3.0 9.8 1.0 CG A:ASP1187 3.1 7.9 1.0 OD1 A:ASP1188 3.3 9.8 1.0 CG A:ASP1060 3.3 9.1 1.0 OD2 A:ASP1187 3.4 7.9 1.0 PA A:ATP2301 3.8 7.6 1.0 OD2 A:ASP1060 3.8 9.1 1.0 C5' A:ATP2301 4.1 7.6 1.0 N A:ASP1188 4.2 9.8 1.0 CB A:ASP1188 4.2 9.8 1.0 C A:ASP1187 4.4 7.9 1.0 O5' A:ATP2301 4.5 7.6 1.0 CB A:ASP1187 4.5 7.9 1.0 MG A:MG2303 4.5 6.8 1.0 CA A:ASP1188 4.5 9.8 1.0 CB A:ASP1060 4.5 9.1 1.0 O1A A:ATP2301 4.6 7.6 1.0 OG A:SER1186 4.7 9.6 1.0 O3A A:ATP2301 4.7 7.6 1.0 N A:ASP1187 4.8 7.9 1.0 CA A:ASP1187 4.8 7.9 1.0 NZ A:LYS1228 5.0 11.0 1.0

Magnesium binding site 2 out of 2 in the La Crosse Virus Polymerase at Replication Initiation Stage


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of La Crosse Virus Polymerase at Replication Initiation Stage within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2303 b:6.8 occ:1.00 O1B A:ATP2301 2.0 7.6 1.0 OD2 A:ASP1060 2.1 9.1 1.0 OD2 A:ASP1187 2.2 7.9 1.0 O A:MET1061 2.2 8.4 1.0 O1G A:ATP2301 2.3 7.6 1.0 PB A:ATP2301 2.4 7.6 1.0 O3A A:ATP2301 2.5 7.6 1.0 O3B A:ATP2301 2.7 7.6 1.0 PG A:ATP2301 3.0 7.6 1.0 CG A:ASP1060 3.2 9.1 1.0 O2A A:ATP2301 3.3 7.6 1.0 CG A:ASP1187 3.4 7.9 1.0 C A:MET1061 3.4 8.4 1.0 PA A:ATP2301 3.5 7.6 1.0 OD1 A:ASP1060 3.7 9.1 1.0 O2B A:ATP2301 3.9 7.6 1.0 N A:MET1061 4.0 8.4 1.0 OD1 A:ASP1187 4.1 7.9 1.0 O3G A:ATP2301 4.1 7.6 1.0 O2G A:ATP2301 4.1 7.6 1.0 O5' A:ATP2301 4.1 7.6 1.0 CA A:MET1061 4.3 8.4 1.0 N A:SER1062 4.4 8.7 1.0 C5' A:ATP2301 4.4 7.6 1.0 CB A:ASP1060 4.4 9.1 1.0 CB A:ASP1187 4.4 7.9 1.0 NZ A:LYS1228 4.5 11.0 1.0 MG A:MG2302 4.5 9.9 1.0 CA A:SER1062 4.5 8.7 1.0 N A:LYS1063 4.5 8.0 1.0 CB A:TRP1064 4.7 6.0 1.0 ND2 A:ASN1225 4.7 10.3 1.0 N A:TRP1064 4.7 6.0 1.0 O1A A:ATP2301 4.7 7.6 1.0 C A:ASP1060 4.7 9.1 1.0 CB A:MET1061 4.8 8.4 1.0 C A:SER1062 4.9 8.7 1.0

B.Arragain, Q.Durieux Trouilleton, F.Baudin, J.Provaznik, N.Azevedo, S.Cusack, G.Schoehn, H.Malet. Structural Snapshots of La Crosse Virus Polymerase Reveal the Mechanisms Underlying Peribunyaviridae Replication and Transcription. Nat Commun V. 13 902 2022.
ISSN: ESSN 2041-1723
PubMed: 35173159
DOI: 10.1038/S41467-022-28428-Z