Magnesium in PDB 7p0m: Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains

All present enzymatic activity of Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains:
3.4.21.53;

The binding sites of Magnesium atom in the Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains (pdb code 7p0m). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains, PDB code: 7p0m:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1002 b:100.8 occ:1.00 OG1 A:THR530 2.1 103.2 1.0 O3G A:ATP1001 2.1 103.0 1.0 O2B A:ATP1001 3.1 103.0 1.0 PG A:ATP1001 3.4 103.0 1.0 CB A:THR530 3.4 103.2 1.0 O3B A:ATP1001 3.5 103.0 1.0 OD2 A:ASP590 3.6 110.5 1.0 OE2 A:GLU591 3.9 114.1 1.0 PB A:ATP1001 3.9 103.0 1.0 NH2 B:ARG652 4.1 97.8 1.0 O1A A:ATP1001 4.1 103.0 1.0 CG2 A:THR530 4.2 103.2 1.0 O1G A:ATP1001 4.2 103.0 1.0 OG1 A:THR638 4.2 112.7 1.0 CA A:THR530 4.4 103.2 1.0 O2G A:ATP1001 4.4 103.0 1.0 CG A:ASP590 4.4 110.5 1.0 N A:THR530 4.5 103.2 1.0 O3A A:ATP1001 4.7 103.0 1.0 CB A:THR638 4.8 112.7 1.0 CD A:GLU591 5.0 114.1 1.0 PA A:ATP1001 5.0 103.0 1.0

Magnesium binding site 2 out of 4 in the Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1002 b:90.0 occ:1.00 O2G B:ATP1001 2.0 87.7 1.0 OG1 B:THR530 2.1 86.3 1.0 O2B B:ATP1001 2.8 87.7 1.0 PG B:ATP1001 3.2 87.7 1.0 O3B B:ATP1001 3.3 87.7 1.0 CB B:THR530 3.4 86.3 1.0 PB B:ATP1001 3.7 87.7 1.0 O1G B:ATP1001 3.8 87.7 1.0 OG1 B:THR638 3.8 91.0 1.0 N B:THR530 4.1 86.3 1.0 CA B:THR530 4.2 86.3 1.0 NH2 C:ARG652 4.2 88.7 1.0 CB B:THR638 4.3 91.0 1.0 CG2 B:THR530 4.3 86.3 1.0 O3G B:ATP1001 4.4 87.7 1.0 OE2 B:GLU591 4.7 98.0 1.0 O3A B:ATP1001 4.7 87.7 1.0 OD1 B:ASP590 4.7 94.1 1.0 CG2 B:THR638 4.7 91.0 1.0 O1B B:ATP1001 4.8 87.7 1.0 CE B:LYS529 4.8 84.8 1.0 CB B:LYS529 4.8 84.8 1.0 O1A B:ATP1001 5.0 87.7 1.0 C B:LYS529 5.0 84.8 1.0

Magnesium binding site 3 out of 4 in the Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1002 b:97.4 occ:1.00 O2G C:ATP1001 2.0 96.6 1.0 OG1 C:THR530 2.1 92.7 1.0 OE2 C:GLU591 3.1 101.5 1.0 PG C:ATP1001 3.1 96.6 1.0 O2B C:ATP1001 3.2 96.6 1.0 CG2 C:THR638 3.2 95.4 1.0 O1G C:ATP1001 3.4 96.6 1.0 CB C:THR530 3.5 92.7 1.0 O3B C:ATP1001 3.5 96.6 1.0 PB C:ATP1001 4.0 96.6 1.0 CB C:THR638 4.1 95.4 1.0 CD C:GLU591 4.3 101.5 1.0 N C:THR530 4.3 92.7 1.0 CG2 C:THR530 4.3 92.7 1.0 CA C:THR530 4.4 92.7 1.0 O3G C:ATP1001 4.4 96.6 1.0 OG1 C:THR638 4.5 95.4 1.0 CB C:ASP590 4.7 97.6 1.0 OD1 C:ASP590 4.8 97.6 1.0 CG C:GLU591 4.9 101.5 1.0 O1B C:ATP1001 5.0 96.6 1.0

Magnesium binding site 4 out of 4 in the Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Human Mitochondrial Lon Protease with Substrate in the Atpase and Protease Domains within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg1002 b:136.8 occ:1.00 O2B F:ATP1001 2.3 129.3 1.0 OG1 F:THR530 2.5 136.7 1.0 O2G F:ATP1001 2.7 129.3 1.0 OD2 F:ASP590 3.1 152.7 1.0 PB F:ATP1001 3.6 129.3 1.0 CB F:THR530 3.6 136.7 1.0 O3B F:ATP1001 3.7 129.3 1.0 OD1 F:ASP590 3.8 152.7 1.0 PG F:ATP1001 3.8 129.3 1.0 CG F:ASP590 3.8 152.7 1.0 NH2 F:ARG546 4.2 154.6 1.0 CG2 F:THR530 4.3 136.7 1.0 O3A F:ATP1001 4.4 129.3 1.0 O1A F:ATP1001 4.6 129.3 1.0 CZ F:ARG546 4.6 154.6 1.0 O3G F:ATP1001 4.6 129.3 1.0 O1B F:ATP1001 4.6 129.3 1.0 O2A F:ATP1001 4.7 129.3 1.0 PA F:ATP1001 4.8 129.3 1.0 CA F:THR530 4.8 136.7 1.0 N F:THR530 4.9 136.7 1.0 NH1 F:ARG546 4.9 154.6 1.0 O1G F:ATP1001 5.0 129.3 1.0

G.Valentin Gese, S.Shahzad, C.Pardo-Hernandez, A.Wramstedt, M.Falkenberg, M.Hallberg. A Dual Allosteric Pathway Drives Human Mitochondrial Lon To Be Published.