Magnesium in PDB 7pxe: CA2+ Bound Drosophila Slo Channel
Other elements in 7pxe:
The structure of CA2+ Bound Drosophila Slo Channel also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the CA2+ Bound Drosophila Slo Channel
(pdb code 7pxe). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the
CA2+ Bound Drosophila Slo Channel, PDB code: 7pxe:
Jump to Magnesium binding site number:
1;
2;
3;
4;
Magnesium binding site 1 out
of 4 in 7pxe
Go back to
Magnesium Binding Sites List in 7pxe
Magnesium binding site 1 out
of 4 in the CA2+ Bound Drosophila Slo Channel
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg1203
b:54.4
occ:1.00
|
O
|
A:ALA526
|
2.3
|
65.7
|
1.0
|
|
O
|
A:ASN523
|
2.6
|
61.6
|
1.0
|
|
O
|
A:THR547
|
2.6
|
65.3
|
1.0
|
|
OE2
|
A:GLU550
|
2.9
|
65.7
|
1.0
|
|
O
|
A:MET549
|
2.9
|
66.3
|
1.0
|
|
C
|
A:ALA526
|
3.5
|
65.7
|
1.0
|
|
CD
|
A:GLU550
|
3.6
|
65.7
|
1.0
|
|
CG
|
A:GLU550
|
3.6
|
65.7
|
1.0
|
|
C
|
A:THR547
|
3.7
|
65.3
|
1.0
|
|
C
|
A:MET549
|
3.7
|
66.3
|
1.0
|
|
C
|
A:ASN523
|
3.8
|
61.6
|
1.0
|
|
CG
|
A:ARG528
|
3.9
|
68.5
|
1.0
|
|
O
|
A:HOH1303
|
3.9
|
68.3
|
1.0
|
|
N
|
A:ARG528
|
3.9
|
68.5
|
1.0
|
|
N
|
A:MET549
|
4.1
|
66.3
|
1.0
|
|
C
|
A:GLY548
|
4.1
|
64.2
|
1.0
|
|
O
|
A:LEU524
|
4.1
|
61.8
|
1.0
|
|
O
|
A:HOH1315
|
4.2
|
64.6
|
1.0
|
|
CA
|
A:GLY548
|
4.4
|
64.2
|
1.0
|
|
C
|
A:LEU524
|
4.4
|
61.8
|
1.0
|
|
CB
|
A:ARG528
|
4.4
|
68.5
|
1.0
|
|
N
|
A:ALA526
|
4.4
|
65.7
|
1.0
|
|
N
|
A:MET527
|
4.4
|
68.5
|
1.0
|
|
CA
|
A:MET527
|
4.4
|
68.5
|
1.0
|
|
CA
|
A:ALA526
|
4.4
|
65.7
|
1.0
|
|
N
|
A:GLY548
|
4.4
|
64.2
|
1.0
|
|
N
|
A:GLU550
|
4.5
|
65.7
|
1.0
|
|
O
|
A:GLY548
|
4.5
|
64.2
|
1.0
|
|
CA
|
A:LEU524
|
4.5
|
61.8
|
1.0
|
|
CA
|
A:MET549
|
4.6
|
66.3
|
1.0
|
|
CA
|
A:GLU550
|
4.6
|
65.7
|
1.0
|
|
C
|
A:MET527
|
4.6
|
68.5
|
1.0
|
|
N
|
A:LEU524
|
4.6
|
61.8
|
1.0
|
|
CA
|
A:THR547
|
4.6
|
65.3
|
1.0
|
|
CB
|
A:GLU550
|
4.7
|
65.7
|
1.0
|
|
OE1
|
A:GLU550
|
4.7
|
65.7
|
1.0
|
|
CA
|
A:ASN523
|
4.7
|
61.6
|
1.0
|
|
CA
|
A:ARG528
|
4.7
|
68.5
|
1.0
|
|
CB
|
A:ALA526
|
4.7
|
65.7
|
1.0
|
|
O
|
A:ARG528
|
4.8
|
68.5
|
1.0
|
|
CB
|
A:ASN523
|
5.0
|
61.6
|
1.0
|
|
Magnesium binding site 2 out
of 4 in 7pxe
Go back to
Magnesium Binding Sites List in 7pxe
Magnesium binding site 2 out
of 4 in the CA2+ Bound Drosophila Slo Channel
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg1203
b:55.2
occ:1.00
|
O
|
B:ALA526
|
2.3
|
65.2
|
1.0
|
|
O
|
B:ASN523
|
2.6
|
61.3
|
1.0
|
|
O
|
B:THR547
|
2.6
|
65.5
|
1.0
|
|
OE2
|
B:GLU550
|
2.9
|
65.7
|
1.0
|
|
O
|
B:MET549
|
2.9
|
65.9
|
1.0
|
|
C
|
B:ALA526
|
3.5
|
65.2
|
1.0
|
|
CD
|
B:GLU550
|
3.6
|
65.7
|
1.0
|
|
CG
|
B:GLU550
|
3.6
|
65.7
|
1.0
|
|
C
|
B:THR547
|
3.7
|
65.5
|
1.0
|
|
C
|
B:MET549
|
3.7
|
65.9
|
1.0
|
|
C
|
B:ASN523
|
3.8
|
61.3
|
1.0
|
|
CG
|
B:ARG528
|
3.9
|
68.2
|
1.0
|
|
O
|
B:HOH1303
|
3.9
|
67.3
|
1.0
|
|
N
|
B:ARG528
|
3.9
|
68.2
|
1.0
|
|
N
|
B:MET549
|
4.1
|
65.9
|
1.0
|
|
C
|
B:GLY548
|
4.1
|
64.4
|
1.0
|
|
O
|
B:LEU524
|
4.1
|
62.1
|
1.0
|
|
O
|
B:HOH1316
|
4.2
|
64.0
|
1.0
|
|
CA
|
B:GLY548
|
4.4
|
64.4
|
1.0
|
|
C
|
B:LEU524
|
4.4
|
62.1
|
1.0
|
|
CB
|
B:ARG528
|
4.4
|
68.2
|
1.0
|
|
N
|
B:ALA526
|
4.4
|
65.2
|
1.0
|
|
N
|
B:MET527
|
4.4
|
68.2
|
1.0
|
|
CA
|
B:MET527
|
4.4
|
68.2
|
1.0
|
|
CA
|
B:ALA526
|
4.4
|
65.2
|
1.0
|
|
N
|
B:GLY548
|
4.4
|
64.4
|
1.0
|
|
N
|
B:GLU550
|
4.5
|
65.7
|
1.0
|
|
O
|
B:GLY548
|
4.5
|
64.4
|
1.0
|
|
CA
|
B:LEU524
|
4.5
|
62.1
|
1.0
|
|
CA
|
B:MET549
|
4.6
|
65.9
|
1.0
|
|
CA
|
B:GLU550
|
4.6
|
65.7
|
1.0
|
|
C
|
B:MET527
|
4.6
|
68.2
|
1.0
|
|
N
|
B:LEU524
|
4.6
|
62.1
|
1.0
|
|
CA
|
B:THR547
|
4.6
|
65.5
|
1.0
|
|
CB
|
B:GLU550
|
4.7
|
65.7
|
1.0
|
|
OE1
|
B:GLU550
|
4.7
|
65.7
|
1.0
|
|
CA
|
B:ASN523
|
4.7
|
61.3
|
1.0
|
|
CA
|
B:ARG528
|
4.7
|
68.2
|
1.0
|
|
CB
|
B:ALA526
|
4.7
|
65.2
|
1.0
|
|
O
|
B:ARG528
|
4.8
|
68.2
|
1.0
|
|
CB
|
B:ASN523
|
5.0
|
61.3
|
1.0
|
|
Magnesium binding site 3 out
of 4 in 7pxe
Go back to
Magnesium Binding Sites List in 7pxe
Magnesium binding site 3 out
of 4 in the CA2+ Bound Drosophila Slo Channel
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg1203
b:55.0
occ:1.00
|
O
|
C:ALA526
|
2.3
|
65.6
|
1.0
|
|
O
|
C:ASN523
|
2.6
|
61.4
|
1.0
|
|
O
|
C:THR547
|
2.6
|
65.5
|
1.0
|
|
OE2
|
C:GLU550
|
2.9
|
65.9
|
1.0
|
|
O
|
C:MET549
|
2.9
|
65.9
|
1.0
|
|
C
|
C:ALA526
|
3.5
|
65.6
|
1.0
|
|
CD
|
C:GLU550
|
3.6
|
65.9
|
1.0
|
|
CG
|
C:GLU550
|
3.6
|
65.9
|
1.0
|
|
C
|
C:THR547
|
3.7
|
65.5
|
1.0
|
|
C
|
C:MET549
|
3.7
|
65.9
|
1.0
|
|
C
|
C:ASN523
|
3.8
|
61.4
|
1.0
|
|
CG
|
C:ARG528
|
3.9
|
68.6
|
1.0
|
|
O
|
C:HOH1306
|
3.9
|
68.3
|
1.0
|
|
N
|
C:ARG528
|
3.9
|
68.6
|
1.0
|
|
N
|
C:MET549
|
4.1
|
65.9
|
1.0
|
|
C
|
C:GLY548
|
4.1
|
64.2
|
1.0
|
|
O
|
C:LEU524
|
4.1
|
62.3
|
1.0
|
|
O
|
C:HOH1318
|
4.2
|
64.6
|
1.0
|
|
CA
|
C:GLY548
|
4.4
|
64.2
|
1.0
|
|
C
|
C:LEU524
|
4.4
|
62.3
|
1.0
|
|
CB
|
C:ARG528
|
4.4
|
68.6
|
1.0
|
|
N
|
C:ALA526
|
4.4
|
65.6
|
1.0
|
|
N
|
C:MET527
|
4.4
|
68.1
|
1.0
|
|
CA
|
C:MET527
|
4.4
|
68.1
|
1.0
|
|
CA
|
C:ALA526
|
4.4
|
65.6
|
1.0
|
|
N
|
C:GLY548
|
4.4
|
64.2
|
1.0
|
|
N
|
C:GLU550
|
4.5
|
65.9
|
1.0
|
|
O
|
C:GLY548
|
4.5
|
64.2
|
1.0
|
|
CA
|
C:LEU524
|
4.5
|
62.3
|
1.0
|
|
CA
|
C:MET549
|
4.6
|
65.9
|
1.0
|
|
CA
|
C:GLU550
|
4.6
|
65.9
|
1.0
|
|
C
|
C:MET527
|
4.6
|
68.1
|
1.0
|
|
N
|
C:LEU524
|
4.6
|
62.3
|
1.0
|
|
CA
|
C:THR547
|
4.7
|
65.5
|
1.0
|
|
CB
|
C:GLU550
|
4.7
|
65.9
|
1.0
|
|
OE1
|
C:GLU550
|
4.7
|
65.9
|
1.0
|
|
CA
|
C:ASN523
|
4.7
|
61.4
|
1.0
|
|
CA
|
C:ARG528
|
4.7
|
68.6
|
1.0
|
|
CB
|
C:ALA526
|
4.7
|
65.6
|
1.0
|
|
O
|
C:ARG528
|
4.8
|
68.6
|
1.0
|
|
CB
|
C:ASN523
|
5.0
|
61.4
|
1.0
|
|
Magnesium binding site 4 out
of 4 in 7pxe
Go back to
Magnesium Binding Sites List in 7pxe
Magnesium binding site 4 out
of 4 in the CA2+ Bound Drosophila Slo Channel
 Mono view
 Stereo pair view
|
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of CA2+ Bound Drosophila Slo Channel within 5.0Å range:
|
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg1203
b:54.7
occ:1.00
|
O
|
D:ALA526
|
2.3
|
65.1
|
1.0
|
|
O
|
D:ASN523
|
2.6
|
61.2
|
1.0
|
|
O
|
D:THR547
|
2.6
|
65.5
|
1.0
|
|
OE2
|
D:GLU550
|
2.9
|
65.9
|
1.0
|
|
O
|
D:MET549
|
2.9
|
66.3
|
1.0
|
|
C
|
D:ALA526
|
3.5
|
65.1
|
1.0
|
|
CD
|
D:GLU550
|
3.6
|
65.9
|
1.0
|
|
CG
|
D:GLU550
|
3.6
|
65.9
|
1.0
|
|
C
|
D:THR547
|
3.7
|
65.5
|
1.0
|
|
C
|
D:MET549
|
3.7
|
66.3
|
1.0
|
|
C
|
D:ASN523
|
3.8
|
61.2
|
1.0
|
|
CG
|
D:ARG528
|
3.9
|
68.8
|
1.0
|
|
O
|
D:HOH1304
|
3.9
|
67.8
|
1.0
|
|
N
|
D:ARG528
|
3.9
|
68.8
|
1.0
|
|
N
|
D:MET549
|
4.1
|
66.3
|
1.0
|
|
C
|
D:GLY548
|
4.1
|
64.8
|
1.0
|
|
O
|
D:LEU524
|
4.1
|
61.5
|
1.0
|
|
O
|
D:HOH1316
|
4.3
|
64.8
|
1.0
|
|
CA
|
D:GLY548
|
4.4
|
64.8
|
1.0
|
|
C
|
D:LEU524
|
4.4
|
61.5
|
1.0
|
|
CB
|
D:ARG528
|
4.4
|
68.8
|
1.0
|
|
N
|
D:ALA526
|
4.4
|
65.1
|
1.0
|
|
N
|
D:MET527
|
4.4
|
69.2
|
1.0
|
|
CA
|
D:MET527
|
4.4
|
69.2
|
1.0
|
|
CA
|
D:ALA526
|
4.4
|
65.1
|
1.0
|
|
N
|
D:GLY548
|
4.4
|
64.8
|
1.0
|
|
N
|
D:GLU550
|
4.5
|
65.9
|
1.0
|
|
O
|
D:GLY548
|
4.5
|
64.8
|
1.0
|
|
CA
|
D:LEU524
|
4.5
|
61.5
|
1.0
|
|
CA
|
D:MET549
|
4.6
|
66.3
|
1.0
|
|
CA
|
D:GLU550
|
4.6
|
65.9
|
1.0
|
|
C
|
D:MET527
|
4.6
|
69.2
|
1.0
|
|
N
|
D:LEU524
|
4.6
|
61.5
|
1.0
|
|
CA
|
D:THR547
|
4.7
|
65.5
|
1.0
|
|
CB
|
D:GLU550
|
4.7
|
65.9
|
1.0
|
|
OE1
|
D:GLU550
|
4.7
|
65.9
|
1.0
|
|
CA
|
D:ASN523
|
4.7
|
61.2
|
1.0
|
|
CA
|
D:ARG528
|
4.7
|
68.8
|
1.0
|
|
CB
|
D:ALA526
|
4.7
|
65.1
|
1.0
|
|
O
|
D:ARG528
|
4.8
|
68.8
|
1.0
|
|
CB
|
D:ASN523
|
5.0
|
61.2
|
1.0
|
|
Reference:
T.Raisch,
A.Brockmann,
U.Ebbinghaus-Kintscher,
J.Freigang,
O.Gutbrod,
J.Kubicek,
B.Maertens,
O.Hofnagel,
S.Raunser.
Small Molecule Modulation of the Drosophila Slo Channel Elucidated By Cryo-Em To Be Published.
DOI: 10.1038/S41467-021-27435-W
Page generated: Fri Dec 17 10:52:37 2021
|
