Magnesium in PDB 7pxf: CA2+ Free Drosophila Slo Channel

The structure of CA2+ Free Drosophila Slo Channel also contains other interesting chemical elements:

Potassium

(K)

3 atoms

The binding sites of Magnesium atom in the CA2+ Free Drosophila Slo Channel (pdb code 7pxf). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the CA2+ Free Drosophila Slo Channel, PDB code: 7pxf:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the CA2+ Free Drosophila Slo Channel


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of CA2+ Free Drosophila Slo Channel within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1201 b:45.7 occ:1.00 O A:ASN523 2.5 46.7 1.0 O A:ALA526 2.5 49.3 1.0 O A:THR547 2.9 52.5 1.0 O A:MET549 3.2 58.1 1.0 C A:ASN523 3.7 46.7 1.0 C A:ALA526 3.7 49.3 1.0 CG A:GLU550 3.7 60.5 1.0 CG A:ARG528 3.8 55.8 1.0 O A:LEU524 3.8 45.8 1.0 CB A:ARG528 4.0 55.8 1.0 N A:ARG528 4.1 55.8 1.0 C A:THR547 4.1 52.5 1.0 OE2 A:GLU550 4.1 60.5 1.0 C A:LEU524 4.1 45.8 1.0 N A:ALA526 4.2 49.3 1.0 C A:MET549 4.3 58.1 1.0 CA A:LEU524 4.3 45.8 1.0 CD A:GLU550 4.4 60.5 1.0 N A:LEU524 4.5 45.8 1.0 CA A:ALA526 4.5 49.3 1.0 C A:GLY548 4.5 55.5 1.0 N A:MET527 4.6 57.6 1.0 N A:MET549 4.7 58.1 1.0 CA A:ASN523 4.7 46.7 1.0 CA A:ARG528 4.7 55.8 1.0 CA A:GLY548 4.7 55.5 1.0 C A:MET527 4.7 57.6 1.0 CA A:MET527 4.8 57.6 1.0 O A:GLY548 4.8 55.5 1.0 N A:GLY548 4.9 55.5 1.0 N A:PHE525 4.9 44.9 1.0 CB A:GLU550 4.9 60.5 1.0 CA A:GLU550 5.0 60.5 1.0

Magnesium binding site 2 out of 4 in the CA2+ Free Drosophila Slo Channel


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of CA2+ Free Drosophila Slo Channel within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1201 b:45.9 occ:1.00 O B:ASN523 2.5 47.1 1.0 O B:ALA526 2.5 49.8 1.0 O B:THR547 2.9 52.7 1.0 O B:MET549 3.2 57.9 1.0 C B:ASN523 3.7 47.1 1.0 C B:ALA526 3.7 49.8 1.0 CG B:GLU550 3.7 60.1 1.0 CG B:ARG528 3.8 56.3 1.0 O B:LEU524 3.8 45.8 1.0 CB B:ARG528 4.0 56.3 1.0 N B:ARG528 4.1 56.3 1.0 C B:THR547 4.1 52.7 1.0 OE2 B:GLU550 4.1 60.1 1.0 C B:LEU524 4.1 45.8 1.0 N B:ALA526 4.2 49.8 1.0 C B:MET549 4.3 57.9 1.0 CA B:LEU524 4.3 45.8 1.0 CD B:GLU550 4.4 60.1 1.0 N B:LEU524 4.5 45.8 1.0 CA B:ALA526 4.5 49.8 1.0 C B:GLY548 4.5 55.5 1.0 N B:MET527 4.6 58.3 1.0 N B:MET549 4.7 57.9 1.0 CA B:ASN523 4.7 47.1 1.0 CA B:ARG528 4.7 56.3 1.0 CA B:GLY548 4.7 55.5 1.0 C B:MET527 4.7 58.3 1.0 CA B:MET527 4.8 58.3 1.0 O B:GLY548 4.8 55.5 1.0 N B:GLY548 4.9 55.5 1.0 N B:PHE525 4.9 45.1 1.0 CB B:GLU550 4.9 60.1 1.0 CA B:GLU550 5.0 60.1 1.0

Magnesium binding site 3 out of 4 in the CA2+ Free Drosophila Slo Channel


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of CA2+ Free Drosophila Slo Channel within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1201 b:45.2 occ:1.00 O C:ASN523 2.5 46.8 1.0 O C:ALA526 2.5 49.7 1.0 O C:THR547 2.9 52.5 1.0 O C:MET549 3.2 57.9 1.0 C C:ASN523 3.7 46.8 1.0 C C:ALA526 3.7 49.7 1.0 CG C:GLU550 3.7 59.7 1.0 CG C:ARG528 3.8 55.9 1.0 O C:LEU524 3.8 45.6 1.0 CB C:ARG528 4.0 55.9 1.0 N C:ARG528 4.1 55.9 1.0 C C:THR547 4.1 52.5 1.0 OE2 C:GLU550 4.1 59.7 1.0 C C:LEU524 4.1 45.6 1.0 N C:ALA526 4.2 49.7 1.0 C C:MET549 4.3 57.9 1.0 CA C:LEU524 4.3 45.6 1.0 CD C:GLU550 4.4 59.7 1.0 N C:LEU524 4.5 45.6 1.0 CA C:ALA526 4.5 49.7 1.0 C C:GLY548 4.5 55.6 1.0 N C:MET527 4.6 57.8 1.0 N C:MET549 4.7 57.9 1.0 CA C:ASN523 4.7 46.8 1.0 CA C:ARG528 4.7 55.9 1.0 CA C:GLY548 4.7 55.6 1.0 C C:MET527 4.7 57.8 1.0 CA C:MET527 4.8 57.8 1.0 O C:GLY548 4.8 55.6 1.0 N C:GLY548 4.9 55.6 1.0 N C:PHE525 4.9 45.0 1.0 CB C:GLU550 4.9 59.7 1.0 CA C:GLU550 5.0 59.7 1.0

Magnesium binding site 4 out of 4 in the CA2+ Free Drosophila Slo Channel


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of CA2+ Free Drosophila Slo Channel within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1201 b:46.3 occ:1.00 O D:ASN523 2.5 47.3 1.0 O D:ALA526 2.5 49.6 1.0 O D:THR547 2.9 52.9 1.0 O D:MET549 3.2 58.1 1.0 C D:ASN523 3.7 47.3 1.0 C D:ALA526 3.7 49.6 1.0 CG D:GLU550 3.7 60.5 1.0 CG D:ARG528 3.8 55.9 1.0 O D:LEU524 3.8 45.8 1.0 CB D:ARG528 4.0 55.9 1.0 N D:ARG528 4.1 55.9 1.0 C D:THR547 4.1 52.9 1.0 OE2 D:GLU550 4.1 60.5 1.0 C D:LEU524 4.1 45.8 1.0 N D:ALA526 4.2 49.6 1.0 C D:MET549 4.2 58.1 1.0 CA D:LEU524 4.3 45.8 1.0 CD D:GLU550 4.4 60.5 1.0 N D:LEU524 4.5 45.8 1.0 CA D:ALA526 4.5 49.6 1.0 C D:GLY548 4.5 56.2 1.0 N D:MET527 4.6 57.7 1.0 N D:MET549 4.7 58.1 1.0 CA D:ASN523 4.7 47.3 1.0 CA D:ARG528 4.7 55.9 1.0 CA D:GLY548 4.7 56.2 1.0 C D:MET527 4.7 57.7 1.0 CA D:MET527 4.8 57.7 1.0 O D:GLY548 4.8 56.2 1.0 N D:GLY548 4.9 56.2 1.0 N D:PHE525 4.9 45.2 1.0 CB D:GLU550 4.9 60.5 1.0 CA D:GLU550 5.0 60.5 1.0

T.Raisch, A.Brockmann, U.Ebbinghaus-Kintscher, J.Freigang, O.Gutbrod, J.Kubicek, B.Maertens, O.Hofnagel, S.Raunser. Small Molecule Modulation of the Drosophila Slo Channel Elucidated By Cryo-Em To Be Published.
DOI: 10.1038/S41467-021-27435-W