Magnesium in PDB 7pxg: Verruculogen-Bound Drosophila Slo Channel
Other elements in 7pxg:
The structure of Verruculogen-Bound Drosophila Slo Channel also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Verruculogen-Bound Drosophila Slo Channel
(pdb code 7pxg). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the
Verruculogen-Bound Drosophila Slo Channel, PDB code: 7pxg:
Jump to Magnesium binding site number:
1;
2;
3;
4;
Magnesium binding site 1 out
of 4 in 7pxg
Go back to
Magnesium Binding Sites List in 7pxg
Magnesium binding site 1 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
A:Mg2004
b:32.3
occ:1.00
|
O
|
A:ASN523
|
2.3
|
39.0
|
1.0
|
O
|
A:ALA526
|
2.4
|
43.8
|
1.0
|
O
|
A:THR547
|
2.5
|
43.8
|
1.0
|
O
|
A:MET549
|
2.8
|
48.4
|
1.0
|
CG
|
A:GLU550
|
3.4
|
47.5
|
1.0
|
OE2
|
A:GLU550
|
3.5
|
47.5
|
1.0
|
C
|
A:ASN523
|
3.6
|
39.0
|
1.0
|
C
|
A:ALA526
|
3.6
|
43.8
|
1.0
|
C
|
A:THR547
|
3.7
|
43.8
|
1.0
|
C
|
A:MET549
|
3.7
|
48.4
|
1.0
|
CD
|
A:GLU550
|
3.8
|
47.5
|
1.0
|
CG
|
A:ARG528
|
3.9
|
49.0
|
1.0
|
CB
|
A:ARG528
|
4.0
|
49.0
|
1.0
|
N
|
A:ALA526
|
4.1
|
43.8
|
1.0
|
N
|
A:ARG528
|
4.2
|
49.0
|
1.0
|
C
|
A:GLY548
|
4.2
|
45.5
|
1.0
|
CA
|
A:ALA526
|
4.3
|
43.8
|
1.0
|
CA
|
A:GLU550
|
4.4
|
47.5
|
1.0
|
N
|
A:GLU550
|
4.4
|
47.5
|
1.0
|
N
|
A:MET549
|
4.4
|
48.4
|
1.0
|
O
|
A:GLY548
|
4.4
|
45.5
|
1.0
|
CA
|
A:LEU524
|
4.4
|
39.8
|
1.0
|
CA
|
A:ASN523
|
4.4
|
39.0
|
1.0
|
N
|
A:LEU524
|
4.5
|
39.8
|
1.0
|
CB
|
A:GLU550
|
4.5
|
47.5
|
1.0
|
C
|
A:LEU524
|
4.5
|
39.8
|
1.0
|
CA
|
A:THR547
|
4.6
|
43.8
|
1.0
|
CA
|
A:GLY548
|
4.6
|
45.5
|
1.0
|
CB
|
A:ALA526
|
4.6
|
43.8
|
1.0
|
N
|
A:GLY548
|
4.6
|
45.5
|
1.0
|
N
|
A:MET527
|
4.7
|
48.7
|
1.0
|
CA
|
A:ARG528
|
4.7
|
49.0
|
1.0
|
CA
|
A:MET549
|
4.7
|
48.4
|
1.0
|
O
|
A:LEU524
|
4.7
|
39.8
|
1.0
|
CB
|
A:ASN523
|
4.8
|
39.0
|
1.0
|
N
|
A:PHE525
|
4.8
|
40.6
|
1.0
|
C
|
A:MET527
|
4.8
|
48.7
|
1.0
|
OE1
|
A:GLU550
|
4.8
|
47.5
|
1.0
|
CA
|
A:MET527
|
4.8
|
48.7
|
1.0
|
|
Magnesium binding site 2 out
of 4 in 7pxg
Go back to
Magnesium Binding Sites List in 7pxg
Magnesium binding site 2 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
B:Mg2004
b:33.0
occ:1.00
|
O
|
B:ASN523
|
2.3
|
39.4
|
1.0
|
O
|
B:ALA526
|
2.4
|
43.9
|
1.0
|
O
|
B:THR547
|
2.5
|
45.0
|
1.0
|
O
|
B:MET549
|
2.8
|
48.6
|
1.0
|
CG
|
B:GLU550
|
3.4
|
48.2
|
1.0
|
OE2
|
B:GLU550
|
3.5
|
48.2
|
1.0
|
C
|
B:ASN523
|
3.6
|
39.4
|
1.0
|
C
|
B:ALA526
|
3.6
|
43.9
|
1.0
|
C
|
B:THR547
|
3.7
|
45.0
|
1.0
|
C
|
B:MET549
|
3.7
|
48.6
|
1.0
|
CD
|
B:GLU550
|
3.8
|
48.2
|
1.0
|
CG
|
B:ARG528
|
3.9
|
49.8
|
1.0
|
CB
|
B:ARG528
|
4.0
|
49.8
|
1.0
|
N
|
B:ALA526
|
4.1
|
43.9
|
1.0
|
N
|
B:ARG528
|
4.2
|
49.8
|
1.0
|
C
|
B:GLY548
|
4.2
|
46.8
|
1.0
|
CA
|
B:ALA526
|
4.3
|
43.9
|
1.0
|
CA
|
B:GLU550
|
4.4
|
48.2
|
1.0
|
N
|
B:GLU550
|
4.4
|
48.2
|
1.0
|
N
|
B:MET549
|
4.4
|
48.6
|
1.0
|
O
|
B:GLY548
|
4.4
|
46.8
|
1.0
|
CA
|
B:LEU524
|
4.4
|
39.9
|
1.0
|
CA
|
B:ASN523
|
4.4
|
39.4
|
1.0
|
N
|
B:LEU524
|
4.5
|
39.9
|
1.0
|
CB
|
B:GLU550
|
4.5
|
48.2
|
1.0
|
C
|
B:LEU524
|
4.5
|
39.9
|
1.0
|
CA
|
B:THR547
|
4.6
|
45.0
|
1.0
|
CA
|
B:GLY548
|
4.6
|
46.8
|
1.0
|
CB
|
B:ALA526
|
4.6
|
43.9
|
1.0
|
N
|
B:GLY548
|
4.6
|
46.8
|
1.0
|
N
|
B:MET527
|
4.7
|
49.3
|
1.0
|
CA
|
B:ARG528
|
4.7
|
49.8
|
1.0
|
CA
|
B:MET549
|
4.7
|
48.6
|
1.0
|
O
|
B:LEU524
|
4.7
|
39.9
|
1.0
|
CB
|
B:ASN523
|
4.8
|
39.4
|
1.0
|
N
|
B:PHE525
|
4.8
|
40.6
|
1.0
|
C
|
B:MET527
|
4.8
|
49.3
|
1.0
|
OE1
|
B:GLU550
|
4.8
|
48.2
|
1.0
|
CA
|
B:MET527
|
4.8
|
49.3
|
1.0
|
|
Magnesium binding site 3 out
of 4 in 7pxg
Go back to
Magnesium Binding Sites List in 7pxg
Magnesium binding site 3 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
C:Mg1205
b:32.2
occ:1.00
|
O
|
C:ASN523
|
2.3
|
39.9
|
1.0
|
O
|
C:ALA526
|
2.4
|
43.7
|
1.0
|
O
|
C:THR547
|
2.5
|
44.8
|
1.0
|
O
|
C:MET549
|
2.8
|
49.1
|
1.0
|
CG
|
C:GLU550
|
3.4
|
48.2
|
1.0
|
OE2
|
C:GLU550
|
3.5
|
48.2
|
1.0
|
C
|
C:ASN523
|
3.6
|
39.9
|
1.0
|
C
|
C:ALA526
|
3.6
|
43.7
|
1.0
|
C
|
C:THR547
|
3.7
|
44.8
|
1.0
|
C
|
C:MET549
|
3.7
|
49.1
|
1.0
|
CD
|
C:GLU550
|
3.8
|
48.2
|
1.0
|
CG
|
C:ARG528
|
3.9
|
50.8
|
1.0
|
CB
|
C:ARG528
|
4.0
|
50.8
|
1.0
|
N
|
C:ALA526
|
4.1
|
43.7
|
1.0
|
N
|
C:ARG528
|
4.2
|
50.8
|
1.0
|
C
|
C:GLY548
|
4.2
|
47.1
|
1.0
|
CA
|
C:ALA526
|
4.3
|
43.7
|
1.0
|
CA
|
C:GLU550
|
4.4
|
48.2
|
1.0
|
N
|
C:GLU550
|
4.4
|
48.2
|
1.0
|
N
|
C:MET549
|
4.4
|
49.1
|
1.0
|
O
|
C:GLY548
|
4.4
|
47.1
|
1.0
|
CA
|
C:LEU524
|
4.4
|
39.9
|
1.0
|
CA
|
C:ASN523
|
4.4
|
39.9
|
1.0
|
N
|
C:LEU524
|
4.5
|
39.9
|
1.0
|
CB
|
C:GLU550
|
4.5
|
48.2
|
1.0
|
C
|
C:LEU524
|
4.5
|
39.9
|
1.0
|
CA
|
C:THR547
|
4.6
|
44.8
|
1.0
|
CA
|
C:GLY548
|
4.6
|
47.1
|
1.0
|
CB
|
C:ALA526
|
4.6
|
43.7
|
1.0
|
N
|
C:GLY548
|
4.6
|
47.1
|
1.0
|
N
|
C:MET527
|
4.7
|
49.2
|
1.0
|
CA
|
C:ARG528
|
4.7
|
50.8
|
1.0
|
CA
|
C:MET549
|
4.7
|
49.1
|
1.0
|
O
|
C:LEU524
|
4.7
|
39.9
|
1.0
|
CB
|
C:ASN523
|
4.8
|
39.9
|
1.0
|
N
|
C:PHE525
|
4.8
|
40.0
|
1.0
|
C
|
C:MET527
|
4.8
|
49.2
|
1.0
|
OE1
|
C:GLU550
|
4.8
|
48.2
|
1.0
|
CA
|
C:MET527
|
4.8
|
49.2
|
1.0
|
|
Magnesium binding site 4 out
of 4 in 7pxg
Go back to
Magnesium Binding Sites List in 7pxg
Magnesium binding site 4 out
of 4 in the Verruculogen-Bound Drosophila Slo Channel
Mono view
Stereo pair view
|
A full contact list of Magnesium with other atoms in the Mg binding
site number 4 of Verruculogen-Bound Drosophila Slo Channel within 5.0Å range:
probe
|
atom
|
residue
|
distance (Å)
|
B
|
Occ
|
D:Mg2004
b:33.5
occ:1.00
|
O
|
D:ASN523
|
2.3
|
40.4
|
1.0
|
O
|
D:ALA526
|
2.4
|
44.5
|
1.0
|
O
|
D:THR547
|
2.5
|
45.7
|
1.0
|
O
|
D:MET549
|
2.8
|
50.3
|
1.0
|
CG
|
D:GLU550
|
3.4
|
48.6
|
1.0
|
OE2
|
D:GLU550
|
3.5
|
48.6
|
1.0
|
C
|
D:ASN523
|
3.6
|
40.4
|
1.0
|
C
|
D:ALA526
|
3.6
|
44.5
|
1.0
|
C
|
D:THR547
|
3.7
|
45.7
|
1.0
|
C
|
D:MET549
|
3.7
|
50.3
|
1.0
|
CD
|
D:GLU550
|
3.8
|
48.6
|
1.0
|
CG
|
D:ARG528
|
3.9
|
50.1
|
1.0
|
CB
|
D:ARG528
|
4.0
|
50.1
|
1.0
|
N
|
D:ALA526
|
4.1
|
44.5
|
1.0
|
N
|
D:ARG528
|
4.2
|
50.1
|
1.0
|
C
|
D:GLY548
|
4.2
|
47.9
|
1.0
|
CA
|
D:ALA526
|
4.3
|
44.5
|
1.0
|
CA
|
D:GLU550
|
4.4
|
48.6
|
1.0
|
N
|
D:GLU550
|
4.4
|
48.6
|
1.0
|
N
|
D:MET549
|
4.4
|
50.3
|
1.0
|
O
|
D:GLY548
|
4.4
|
47.9
|
1.0
|
CA
|
D:LEU524
|
4.4
|
40.3
|
1.0
|
CA
|
D:ASN523
|
4.4
|
40.4
|
1.0
|
N
|
D:LEU524
|
4.5
|
40.3
|
1.0
|
CB
|
D:GLU550
|
4.5
|
48.6
|
1.0
|
C
|
D:LEU524
|
4.5
|
40.3
|
1.0
|
CA
|
D:THR547
|
4.6
|
45.7
|
1.0
|
CA
|
D:GLY548
|
4.6
|
47.9
|
1.0
|
CB
|
D:ALA526
|
4.6
|
44.5
|
1.0
|
N
|
D:GLY548
|
4.6
|
47.9
|
1.0
|
N
|
D:MET527
|
4.7
|
49.8
|
1.0
|
CA
|
D:ARG528
|
4.7
|
50.1
|
1.0
|
CA
|
D:MET549
|
4.7
|
50.3
|
1.0
|
O
|
D:LEU524
|
4.7
|
40.3
|
1.0
|
CB
|
D:ASN523
|
4.8
|
40.4
|
1.0
|
N
|
D:PHE525
|
4.8
|
41.1
|
1.0
|
C
|
D:MET527
|
4.8
|
49.8
|
1.0
|
OE1
|
D:GLU550
|
4.8
|
48.6
|
1.0
|
CA
|
D:MET527
|
4.8
|
49.8
|
1.0
|
|
Reference:
T.Raisch,
A.Brockmann,
U.Ebbinghaus-Kintscher,
J.Freigang,
O.Gutbrod,
J.Kubicek,
B.Maertens,
O.Hofnagel,
S.Raunser.
Small Molecule Modulation of the Drosophila Slo Channel Elucidated By Cryo-Em To Be Published.
DOI: 10.1038/S41467-021-27435-W
Page generated: Thu Oct 3 04:50:29 2024
|