Magnesium in PDB 7r4c: Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map)

All present enzymatic activity of Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map):
1.6.5.3; 1.6.99.3; 7.1.1.2;

The structure of Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map) also contains other interesting chemical elements:

Potassium	(K)	1 atom
Iodine	(I)	2 atoms
Iron	(Fe)	28 atoms
Chlorine	(Cl)	2 atoms
Zinc	(Zn)	1 atom

The binding sites of Magnesium atom in the Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map) (pdb code 7r4c). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map), PDB code: 7r4c:

Magnesium binding site 1 out of 1 in the Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Bovine Complex I in the Presence of IM1761092, Deactive Class V (Composite Map) within 5.0Å range: probe atom residue distance (Å) B Occ O:Mg402 b:58.2 occ:1.00 O3B O:GTP401 2.2 58.3 1.0 O1A O:GTP401 2.3 58.3 1.0 O O:HOH504 2.5 57.7 1.0 PB O:GTP401 3.1 58.3 1.0 O1B O:GTP401 3.2 58.3 1.0 PG O:GTP401 3.4 58.3 1.0 PA O:GTP401 3.5 58.3 1.0 CB O:SER36 3.6 56.1 1.0 O1G O:GTP401 3.7 58.3 1.0 O3A O:GTP401 3.8 58.3 1.0 O3G O:GTP401 4.0 58.3 1.0 OE1 O:GLU53 4.2 50.4 1.0 OE1 O:GLU125 4.3 51.8 1.0 OG O:SER36 4.3 56.1 1.0 O5' O:GTP401 4.3 58.3 1.0 O2B O:GTP401 4.4 58.3 1.0 O2A O:GTP401 4.5 58.3 1.0 CA O:SER36 4.6 56.1 1.0 O2G O:GTP401 4.7 58.3 1.0 N O:SER36 4.7 56.1 1.0 NZ O:LYS35 4.7 55.7 1.0 CG O:LYS35 4.9 55.7 1.0 C5' O:GTP401 5.0 58.3 1.0

H.R.Bridges, J.N.Blaza, Z.Yin, I.Chung, M.N.Pollak, J.Hirst. Structural Basis of Mammalian Respiratory Complex I Inhibition By Medicinal Biguanides. Science V. 379 351 2023.
ISSN: ESSN 1095-9203
PubMed: 36701435
DOI: 10.1126/SCIENCE.ADE3332