Magnesium in PDB 7sd0: Cryo-Em Structure of the SHOC2:PP1C:Mras Complex

All present enzymatic activity of Cryo-Em Structure of the SHOC2:PP1C:Mras Complex:
3.1.3.16; 3.6.5.2;

The structure of Cryo-Em Structure of the SHOC2:PP1C:Mras Complex also contains other interesting chemical elements:

Manganese

(Mn)

2 atoms

The binding sites of Magnesium atom in the Cryo-Em Structure of the SHOC2:PP1C:Mras Complex (pdb code 7sd0). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryo-Em Structure of the SHOC2:PP1C:Mras Complex, PDB code: 7sd0:

Magnesium binding site 1 out of 1 in the Cryo-Em Structure of the SHOC2:PP1C:Mras Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryo-Em Structure of the SHOC2:PP1C:Mras Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg501 b:108.0 occ:1.00 OG1 B:THR45 1.8 114.6 1.0 OG B:SER27 2.3 108.9 1.0 O2B B:GCP500 2.6 124.3 1.0 O2G B:GCP500 2.6 124.3 1.0 O1G B:GCP500 2.7 124.3 1.0 CB B:THR45 2.8 114.6 1.0 PG B:GCP500 3.0 124.3 1.0 OD2 B:ASP67 3.4 106.2 1.0 C3B B:GCP500 3.4 124.3 1.0 PB B:GCP500 3.5 124.3 1.0 N B:THR45 3.6 114.6 1.0 CB B:SER27 3.7 108.9 1.0 CA B:THR45 3.8 114.6 1.0 CG2 B:THR45 3.9 114.6 1.0 O B:ASP43 4.1 126.2 1.0 O1A B:GCP500 4.1 124.3 1.0 CG B:ASP67 4.2 106.2 1.0 OD1 B:ASP67 4.2 106.2 1.0 O B:THR68 4.2 109.2 1.0 O3A B:GCP500 4.2 124.3 1.0 N B:SER27 4.3 108.9 1.0 CA B:SER27 4.5 108.9 1.0 O3G B:GCP500 4.5 124.3 1.0 PA B:GCP500 4.6 124.3 1.0 C B:PRO44 4.6 119.3 1.0 CE B:LYS26 4.6 108.4 1.0 O1B B:GCP500 4.7 124.3 1.0 O2A B:GCP500 4.8 124.3 1.0 O B:ALA69 4.8 114.7 1.0 CB B:LYS26 4.9 108.4 1.0 C B:THR45 4.9 114.6 1.0 CA B:PRO44 4.9 119.3 1.0

N.P.D.Liau, M.C.Johnson, S.Izadi, L.Gerosa, M.Hammel, J.M.Bruning, T.J.Wendorff, W.Phung, S.G.Hymowitz, J.Sudhamsu. Structural Basis For SHOC2 Modulation of Ras Signalling. Nature V. 609 400 2022.
ISSN: ESSN 1476-4687
PubMed: 35768504
DOI: 10.1038/S41586-022-04838-3