Magnesium in PDB 7sx6: Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core

The structure of Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core, PDB code: 7sx6 was solved by W.D.Tolbert, M.Pazgier, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.46 / 3.40
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	62.209, 68.211, 115.055, 90.26, 102.35, 90.38
R / Rfree (%)	23.4 / 28.7

The structure of Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Magnesium atom in the Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core (pdb code 7sx6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core, PDB code: 7sx6:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core within 5.0Å range: probe atom residue distance (Å) B Occ G:Mg512 b:90.6 occ:1.00 NH2 G:ARG327 4.5 158.5 1.0 CZ G:ARG327 4.6 151.4 1.0 NE G:ARG327 4.7 160.2 1.0

Magnesium binding site 2 out of 3 in the Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg512 b:73.2 occ:1.00 NH1 A:ARG327 3.5 134.1 1.0 OD1 G:ASP107 3.6 171.1 1.0 OD2 G:ASP107 3.7 121.6 1.0 CG G:ASP107 4.0 140.6 1.0 O G:ALA73 4.4 161.0 1.0 O G:LEU52 4.5 144.5 1.0 SG G:CYS54 4.6 150.3 1.0 CZ A:ARG327 4.8 156.9 1.0

Magnesium binding site 3 out of 3 in the Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg513 b:108.5 occ:1.00 ND2 A:ASN448 2.7 182.5 1.0 CG A:ASN448 3.9 146.9 1.0 OG A:SER291 4.4 162.9 1.0 OD1 A:ASN448 4.5 160.6 1.0 CB A:ASN448 5.0 115.1 1.0

W.D.Tolbert, M.Pazgier. Crystal Structure of Broadly Neutralizing Antibody N49P9.3 Fab in Complex with Hiv-1 Clade A/E Strain 93TH057 GP120 Core To Be Published.