Magnesium in PDB 7uux: Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination

All present enzymatic activity of Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination:
2.7.7.86;

The structure of Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination, PDB code: 7uux was solved by S.Wu, S.B.Gabelli, J.Sohn, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.55 / 2.26
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	77.999, 98.192, 143.18, 90, 90, 90
R / Rfree (%)	20.1 / 23.4

The structure of Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

The binding sites of Magnesium atom in the Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination (pdb code 7uux). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination, PDB code: 7uux:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg602 b:45.9 occ:1.00 OE1 A:GLN211 2.1 47.1 1.0 O2G A:ATP601 2.1 41.4 1.0 OD1 A:ASN213 2.1 44.8 1.0 O2B A:ATP601 2.1 41.2 1.0 O A:HOH702 2.1 34.1 1.0 O2A A:ATP601 2.1 43.9 1.0 CG A:ASN213 3.1 42.0 1.0 CD A:GLN211 3.2 48.7 1.0 PB A:ATP601 3.2 45.6 1.0 PA A:ATP601 3.3 45.3 1.0 PG A:ATP601 3.4 43.2 1.0 ND2 A:ASN213 3.4 41.6 1.0 O3A A:ATP601 3.5 41.8 1.0 O3B A:ATP601 3.6 43.8 1.0 NE2 A:GLN211 3.7 59.5 1.0 OG A:SER199 3.8 40.2 1.0 O1G A:ATP601 4.2 39.2 1.0 N A:SER199 4.2 40.0 1.0 O A:GLN211 4.3 44.1 1.0 O5' A:ATP601 4.3 43.8 1.0 C5' A:ATP601 4.3 61.2 1.0 CG A:GLN211 4.4 46.9 1.0 O1A A:ATP601 4.5 56.3 1.0 CB A:ASN213 4.5 39.9 1.0 O3G A:ATP601 4.5 46.4 1.0 O1B A:ATP601 4.6 43.1 1.0 CB A:GLN211 4.6 44.1 1.0 C A:GLN211 4.6 39.7 1.0 CB A:SER199 4.6 38.0 1.0 N A:ASN213 4.8 36.9 1.0 CA A:GLY198 4.9 38.6 1.0 N A:PHE212 5.0 43.2 1.0 C A:GLY198 5.0 36.6 1.0

Magnesium binding site 2 out of 2 in the Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg602 b:53.6 occ:1.00 O1B C:ATP601 2.0 51.7 1.0 O C:HOH703 2.1 41.3 1.0 O2A C:ATP601 2.1 43.2 1.0 OD1 C:ASN213 2.1 55.3 1.0 O1G C:ATP601 2.1 43.1 1.0 OE1 C:GLN211 2.2 74.7 1.0 PB C:ATP601 3.1 47.0 1.0 CG C:ASN213 3.1 46.7 1.0 PA C:ATP601 3.3 48.0 1.0 O3A C:ATP601 3.3 45.1 1.0 CD C:GLN211 3.3 59.0 1.0 PG C:ATP601 3.4 44.8 1.0 O3B C:ATP601 3.5 44.5 1.0 ND2 C:ASN213 3.6 50.5 1.0 OG C:SER199 3.8 44.2 1.0 NE2 C:GLN211 4.0 57.6 1.0 N C:SER199 4.1 41.5 1.0 C5' C:ATP601 4.1 61.6 1.0 O C:HOH707 4.2 37.5 1.0 O5' C:ATP601 4.2 52.0 1.0 O3G C:ATP601 4.2 45.1 1.0 O C:GLN211 4.4 49.7 1.0 O2B C:ATP601 4.4 45.4 1.0 CG C:GLN211 4.5 56.2 1.0 O1A C:ATP601 4.5 44.8 1.0 CB C:ASN213 4.5 50.9 1.0 O2G C:ATP601 4.5 49.8 1.0 CB C:SER199 4.6 44.4 1.0 CB C:GLN211 4.6 52.4 1.0 CA C:GLY198 4.7 43.5 1.0 C C:GLN211 4.7 50.0 1.0 C C:GLY198 4.8 40.8 1.0 N C:ASN213 4.9 44.1 1.0 CA C:SER199 4.9 39.4 1.0

S.Wu, S.B.Gabelli, J.S.Sohn. Atp Binds to Cyclic Gmp Amp Synthase (Cgas) Through Mg Coordination To Be Published.