Magnesium in PDB 7uwh: Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate

Enzymatic activity of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate

All present enzymatic activity of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate:
2.7.7.6; 3.1.26.4;

Other elements in 7uwh:

The structure of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate also contains other interesting chemical elements:

Zinc

(Zn)

2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate (pdb code 7uwh). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate, PDB code: 7uwh:

Magnesium binding site 1 out of 1 in 7uwh

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Magnesium Binding Sites List in 7uwh

Magnesium binding site 1 out of 1 in the Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate

Mono view

Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Cryoem Structure of E. Coli Transcription-Coupled Ribonucleotide Excision Repair (Tc-Rer) Complex Bound to Ribonucleotide Substrate within 5.0Å range:

probe	atom	residue	distance (Å)	B	Occ
J:Mg1503 b:6.5 occ:1.00	O3'	R:A20	2.1	16.7	1.0
	OD1	J:ASP460	2.1	6.3	1.0
	OD1	J:ASP462	2.2	8.5	1.0
	OD1	J:ASP464	2.2	12.0	1.0
	CG	J:ASP464	3.0	12.0	1.0
	CG	J:ASP462	3.0	8.5	1.0
	OD2	J:ASP464	3.0	12.0	1.0
	CG	J:ASP460	3.1	6.3	1.0
	OD2	J:ASP462	3.2	8.5	1.0
	C3'	R:A20	3.4	16.7	1.0
	OD2	J:ASP460	3.5	6.3	1.0
	O2'	R:A20	3.7	16.7	1.0
	C4'	R:A20	3.9	16.7	1.0
	NH2	J:ARG425	4.0	16.7	1.0
	C2'	R:A20	4.1	16.7	1.0
	O	J:ASP460	4.2	6.3	1.0
	CB	J:ASP462	4.3	8.5	1.0
	N	J:ASP460	4.3	6.3	1.0
	CB	J:ASP464	4.4	12.0	1.0
	C	J:ASP460	4.4	6.3	1.0
	CB	J:ASP460	4.4	6.3	1.0
	C5'	R:A20	4.5	16.7	1.0
	N	J:ASP462	4.5	8.5	1.0
	CA	J:ASP460	4.6	6.3	1.0
	N	J:ASP464	4.7	12.0	1.0
	CA	J:ASP462	4.9	8.5	1.0
	CA	J:ASP464	5.0	12.0	1.0

Reference:

Z.Hao, M.Gowder, S.Proshkin, B.K.Bharati, V.Epshtein, V.Svetlov, I.Shamovsky, E.Nudler. Rna Polymerase Drives Ribonucleotide Excision Dna Repair in E. Coli. Cell 2023.
ISSN: ISSN 1097-4172
PubMed: 37196657
DOI: 10.1016/J.CELL.2023.04.029

Page generated: Thu Oct 3 10:15:48 2024

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