Magnesium in PDB 7vox: The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2

The structure of The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2, PDB code: 7vox was solved by Y.Choi, H.J.Yoon, H.H.Lee, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.98 / 2.10
Space group	C 2 2 2
Cell size a, b, c (Å), α, β, γ (°)	138.547, 144.291, 75.034, 90, 90, 90
R / Rfree (%)	18.6 / 21.2

The binding sites of Magnesium atom in the The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2 (pdb code 7vox). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2, PDB code: 7vox:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg301 b:10.9 occ:1.00 OG A:SER177 2.9 19.6 1.0 OG C:SER177 3.0 21.7 1.0 N A:SER174 3.2 9.7 1.0 N C:SER174 3.2 14.0 1.0 CB A:SER177 3.5 14.5 1.0 CB C:SER177 3.5 12.0 1.0 OG A:SER174 3.6 12.1 1.0 CA A:TYR173 3.6 11.8 1.0 CA C:TYR173 3.7 17.0 1.0 OG C:SER174 3.7 15.5 1.0 C A:TYR173 3.9 10.8 1.0 O C:HOH307 3.9 38.5 1.0 O A:HOH409 3.9 20.5 1.0 C C:TYR173 3.9 15.7 1.0 CB A:SER174 3.9 15.9 1.0 CB C:SER174 4.0 14.6 1.0 O C:PRO172 4.1 15.0 1.0 CA A:SER174 4.2 12.8 1.0 O A:PRO172 4.2 18.4 1.0 CA C:SER174 4.2 13.9 1.0 CB A:TYR173 4.4 13.8 1.0 CD1 C:TYR173 4.4 13.8 1.0 CD1 A:TYR173 4.4 17.5 1.0 CB C:TYR173 4.5 15.3 1.0 N C:TYR173 4.6 17.8 1.0 N A:TYR173 4.6 15.4 1.0 O D:HOH138 4.7 35.1 1.0 C C:PRO172 4.7 18.2 1.0 C A:PRO172 4.7 23.1 1.0 CG A:TYR173 4.9 21.4 1.0 CG C:TYR173 4.9 22.2 1.0 CA A:SER177 4.9 13.8 1.0 CA C:SER177 5.0 17.1 1.0

Magnesium binding site 2 out of 2 in the The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of The Crystal Structure of Human Forkhead Box Protein A in Complex with Dna 2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg301 b:7.9 occ:1.00 OG B:SER177 2.9 20.0 1.0 OG H:SER177 3.0 14.2 1.0 N H:SER174 3.2 12.9 1.0 N B:SER174 3.2 9.6 1.0 CB H:SER177 3.5 16.4 1.0 CB B:SER177 3.5 20.5 1.0 OG B:SER174 3.6 14.1 1.0 CA H:TYR173 3.6 11.4 1.0 OG H:SER174 3.6 14.0 1.0 CA B:TYR173 3.7 15.2 1.0 O B:HOH410 3.8 23.4 1.0 O H:HOH310 3.8 24.8 1.0 C H:TYR173 3.9 12.8 1.0 C B:TYR173 4.0 12.9 1.0 CB B:SER174 4.0 13.0 1.0 CB H:SER174 4.0 11.9 1.0 CA B:SER174 4.2 15.0 1.0 CA H:SER174 4.2 12.8 1.0 O H:PRO172 4.2 11.7 1.0 O B:PRO172 4.3 16.4 1.0 CD1 H:TYR173 4.3 15.2 1.0 CB H:TYR173 4.3 15.0 1.0 CD1 B:TYR173 4.4 20.8 1.0 CB B:TYR173 4.4 18.3 1.0 N H:TYR173 4.6 15.2 1.0 N B:TYR173 4.6 15.4 1.0 C H:PRO172 4.7 20.4 1.0 O F:HOH141 4.8 27.1 1.0 C B:PRO172 4.8 20.6 1.0 O G:HOH145 4.8 35.8 1.0 CG H:TYR173 4.8 18.5 1.0 CG B:TYR173 4.9 20.8 1.0 CA H:SER177 4.9 17.4 1.0 CA B:SER177 4.9 19.5 1.0

Y.Choi, Y.Luo, S.Lee, H.Jin, H.J.Yoon, Y.Hahn, J.Bae, H.H.Lee. FOXL2 and FOXA1 Cooperatively Assemble on the TP53 Promoter in Alternative Dimer Configurations. Nucleic Acids Res. V. 50 8929 2022.
ISSN: ESSN 1362-4962
PubMed: 35920317
DOI: 10.1093/NAR/GKAC673