Magnesium in PDB 7w4o: The Structure of Katp H175K Mutant in Pre-Open State

The structure of The Structure of Katp H175K Mutant in Pre-Open State also contains other interesting chemical elements:

Chlorine

(Cl)

4 atoms

The binding sites of Magnesium atom in the The Structure of Katp H175K Mutant in Pre-Open State (pdb code 7w4o). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 8 binding sites of Magnesium where determined in the The Structure of Katp H175K Mutant in Pre-Open State, PDB code: 7w4o:
Jump to Magnesium binding site number: 1; 2; 3; 4; 5; 6; 7; 8;

Magnesium binding site 1 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1602 b:49.5 occ:1.00 OE1 B:GLN775 2.2 54.5 1.0 O1B B:ATP1605 2.3 58.1 1.0 CB B:SER720 2.7 40.6 1.0 OD2 B:ASP854 2.9 64.8 1.0 CD B:GLN775 3.1 54.1 1.0 OD1 B:ASP854 3.2 63.7 1.0 CG B:ASP854 3.4 59.5 1.0 OG B:SER720 3.5 59.0 1.0 PB B:ATP1605 3.6 51.6 1.0 CA B:SER720 3.7 34.8 1.0 NE2 B:GLN775 3.7 61.8 1.0 N B:SER720 3.8 36.0 1.0 O2G B:ATP1605 3.8 57.8 1.0 O3B B:ATP1605 4.1 48.8 1.0 CB B:GLN775 4.1 47.0 1.0 CG B:GLN775 4.1 54.0 1.0 O3A B:ATP1605 4.3 43.9 1.0 PG B:ATP1605 4.5 59.4 1.0 O1A B:ATP1605 4.7 47.4 1.0 O2B B:ATP1605 4.8 46.9 1.0 O1G B:ATP1605 4.8 64.4 1.0 CB B:ASP854 4.9 49.4 1.0 C B:LYS719 5.0 40.8 1.0

Magnesium binding site 2 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1603 b:63.8 occ:1.00 O2B B:ADP1601 2.3 68.4 1.0 O3B B:ADP1601 2.9 65.2 1.0 PB B:ADP1601 3.1 62.8 1.0 CB B:SER1386 3.5 62.9 1.0 OE1 B:GLU1507 3.7 98.3 1.0 O1B B:ADP1601 4.1 67.5 1.0 OG B:SER1386 4.2 68.9 1.0 O2A B:ADP1601 4.3 59.8 1.0 O3A B:ADP1601 4.3 64.5 1.0 N B:SER1386 4.6 58.7 1.0 CD B:GLU1507 4.6 95.3 1.0 CA B:SER1386 4.6 55.0 1.0 PA B:ADP1601 4.7 65.0 1.0 OE2 B:GLU1507 4.8 96.0 1.0 NE2 B:GLN1427 4.8 81.7 1.0 NZ B:LYS1385 4.9 70.5 1.0 O1A B:ADP1601 4.9 68.2 1.0

Magnesium binding site 3 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1602 b:49.5 occ:1.00 OE1 D:GLN775 2.2 54.5 1.0 O1B D:ATP1605 2.3 58.1 1.0 CB D:SER720 2.7 40.6 1.0 OD2 D:ASP854 2.9 64.8 1.0 CD D:GLN775 3.1 54.1 1.0 OD1 D:ASP854 3.2 63.7 1.0 CG D:ASP854 3.4 59.5 1.0 OG D:SER720 3.5 59.0 1.0 PB D:ATP1605 3.6 51.6 1.0 CA D:SER720 3.7 34.8 1.0 NE2 D:GLN775 3.7 61.8 1.0 N D:SER720 3.8 36.0 1.0 O2G D:ATP1605 3.8 57.8 1.0 O3B D:ATP1605 4.1 48.8 1.0 CB D:GLN775 4.1 47.0 1.0 CG D:GLN775 4.1 54.0 1.0 O3A D:ATP1605 4.3 43.9 1.0 PG D:ATP1605 4.5 59.4 1.0 O1A D:ATP1605 4.7 47.4 1.0 O2B D:ATP1605 4.8 46.9 1.0 O1G D:ATP1605 4.8 64.4 1.0 CB D:ASP854 4.9 49.4 1.0 C D:LYS719 5.0 40.8 1.0

Magnesium binding site 4 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1603 b:63.8 occ:1.00 O2B D:ADP1601 2.3 68.4 1.0 O3B D:ADP1601 2.9 65.2 1.0 PB D:ADP1601 3.1 62.8 1.0 CB D:SER1386 3.5 62.9 1.0 OE1 D:GLU1507 3.7 98.3 1.0 O1B D:ADP1601 4.1 67.5 1.0 OG D:SER1386 4.2 68.9 1.0 O2A D:ADP1601 4.3 59.8 1.0 O3A D:ADP1601 4.3 64.5 1.0 N D:SER1386 4.6 58.7 1.0 CD D:GLU1507 4.6 95.3 1.0 CA D:SER1386 4.6 55.0 1.0 PA D:ADP1601 4.7 65.0 1.0 OE2 D:GLU1507 4.8 96.0 1.0 NE2 D:GLN1427 4.8 81.7 1.0 NZ D:LYS1385 4.9 70.5 1.0 O1A D:ADP1601 4.9 68.2 1.0

Magnesium binding site 5 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 5 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg1602 b:49.5 occ:1.00 OE1 F:GLN775 2.2 54.5 1.0 O1B F:ATP1605 2.3 58.1 1.0 CB F:SER720 2.7 40.6 1.0 OD2 F:ASP854 2.9 64.8 1.0 CD F:GLN775 3.1 54.1 1.0 OD1 F:ASP854 3.2 63.7 1.0 CG F:ASP854 3.4 59.5 1.0 OG F:SER720 3.5 59.0 1.0 PB F:ATP1605 3.6 51.6 1.0 CA F:SER720 3.7 34.8 1.0 NE2 F:GLN775 3.7 61.8 1.0 N F:SER720 3.8 36.0 1.0 O2G F:ATP1605 3.8 57.8 1.0 O3B F:ATP1605 4.1 48.8 1.0 CB F:GLN775 4.1 47.0 1.0 CG F:GLN775 4.1 54.0 1.0 O3A F:ATP1605 4.3 43.9 1.0 PG F:ATP1605 4.5 59.4 1.0 O1A F:ATP1605 4.7 47.4 1.0 O2B F:ATP1605 4.8 46.9 1.0 O1G F:ATP1605 4.8 64.4 1.0 CB F:ASP854 4.9 49.4 1.0 C F:LYS719 5.0 40.8 1.0

Magnesium binding site 6 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 6 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ F:Mg1603 b:63.8 occ:1.00 O2B F:ADP1601 2.3 68.4 1.0 O3B F:ADP1601 2.9 65.2 1.0 PB F:ADP1601 3.1 62.8 1.0 CB F:SER1386 3.5 62.9 1.0 OE1 F:GLU1507 3.7 98.3 1.0 O1B F:ADP1601 4.1 67.5 1.0 OG F:SER1386 4.2 68.9 1.0 O2A F:ADP1601 4.3 59.8 1.0 O3A F:ADP1601 4.3 64.5 1.0 N F:SER1386 4.6 58.7 1.0 CD F:GLU1507 4.6 95.3 1.0 CA F:SER1386 4.6 55.0 1.0 PA F:ADP1601 4.7 65.0 1.0 OE2 F:GLU1507 4.8 96.0 1.0 NE2 F:GLN1427 4.8 81.7 1.0 NZ F:LYS1385 4.9 70.5 1.0 O1A F:ADP1601 4.9 68.2 1.0

Magnesium binding site 7 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 7 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg1602 b:49.5 occ:1.00 OE1 H:GLN775 2.2 54.5 1.0 O1B H:ATP1605 2.3 58.1 1.0 CB H:SER720 2.7 40.6 1.0 OD2 H:ASP854 2.9 64.8 1.0 CD H:GLN775 3.1 54.1 1.0 OD1 H:ASP854 3.2 63.7 1.0 CG H:ASP854 3.4 59.5 1.0 OG H:SER720 3.5 59.0 1.0 PB H:ATP1605 3.6 51.6 1.0 CA H:SER720 3.7 34.8 1.0 NE2 H:GLN775 3.7 61.8 1.0 N H:SER720 3.8 36.0 1.0 O2G H:ATP1605 3.8 57.8 1.0 O3B H:ATP1605 4.1 48.8 1.0 CB H:GLN775 4.1 47.0 1.0 CG H:GLN775 4.1 54.0 1.0 O3A H:ATP1605 4.3 43.9 1.0 PG H:ATP1605 4.5 59.4 1.0 O1A H:ATP1605 4.7 47.4 1.0 O2B H:ATP1605 4.8 46.9 1.0 O1G H:ATP1605 4.8 64.4 1.0 CB H:ASP854 4.9 49.4 1.0 C H:LYS719 5.0 40.8 1.0

Magnesium binding site 8 out of 8 in the The Structure of Katp H175K Mutant in Pre-Open State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 8 of The Structure of Katp H175K Mutant in Pre-Open State within 5.0Å range: probe atom residue distance (Å) B Occ H:Mg1603 b:63.8 occ:1.00 O2B H:ADP1601 2.3 68.4 1.0 O3B H:ADP1601 2.9 65.2 1.0 PB H:ADP1601 3.1 62.8 1.0 CB H:SER1386 3.5 62.9 1.0 OE1 H:GLU1507 3.7 98.3 1.0 O1B H:ADP1601 4.1 67.5 1.0 OG H:SER1386 4.2 68.9 1.0 O2A H:ADP1601 4.3 59.8 1.0 O3A H:ADP1601 4.3 64.5 1.0 N H:SER1386 4.6 58.7 1.0 CD H:GLU1507 4.6 95.3 1.0 CA H:SER1386 4.6 55.0 1.0 PA H:ADP1601 4.7 65.0 1.0 OE2 H:GLU1507 4.8 96.0 1.0 NE2 H:GLN1427 4.8 81.7 1.0 NZ H:LYS1385 4.9 70.5 1.0 O1A H:ADP1601 4.9 68.2 1.0

M.Wang, J.X.Wu, D.Ding, L.Chen. Structural Insights Into the Mechanism of Pancreatic K Atp Channel Regulation By Nucleotides. Nat Commun V. 13 2770 2022.
ISSN: ESSN 2041-1723
PubMed: 35589716
DOI: 10.1038/S41467-022-30430-4